Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Siew Cheng Wong"'
Autor:
Tsung Wen Chong, June Jingyi Tai, Shazib Pervaiz, Siew Cheng Wong, Gregory Lucien Bellot, Binbin Wang, Herbert Schwarz, Kartini Iskandar, Fera Yiqian Goh
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports
Scientific Reports
Sepsis is a potentially fatal condition triggered by systemic inflammatory response to infection. Due to the heightened immune reactivity and multi-organ pathology, treatment options are limited and several clinical trials have not produced the desir
Publikováno v:
The FASEB Journal. 34:11133-11142
Vitamin D deficiency is a major public health problem worldwide, linked to several chronic diseases including cardiovascular diseases. While immunomodulatory effects of vitamin D on monocytes have been reported in cardiovascular and metabolic disease
Autor:
Jasmine Tan, Alessandra Mortellaro, Hweixian Leong Penny, Joe Yeong, Jean-Pierre Abastado, Hanif Javanmard Khameneh, Dilip Kumar, Christopher I Johnson, Florent Ginhoux, Siew Cheng Wong, Mai Chan Lau, Cindy Phua, Jinmiao Chen, Olaf Rötzschke, Han Chong Toh, Wei Hseun Yeap, Angela Pang, Hao Chen, Baptiste Janela, Justin A. Kenkel, Bernett Lee, Edgar G. Engleman, Diana Lim, Yvonne Nga, Tony Lim Kiat Hon, Je Lin Sieow, Florida Toh, Sin Yee Gun
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6350, p 6350 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 12
International Journal of Molecular Sciences
Volume 22
Issue 12
Inflammation in the tumor microenvironment has been shown to promote disease progression in pancreatic ductal adenocarcinoma (PDAC)
however, the role of macrophage metabolism in promoting inflammation is unclear. Using an orthotopic mouse model
however, the role of macrophage metabolism in promoting inflammation is unclear. Using an orthotopic mouse model
Autor:
Foo Shihui, Heather L. Wilson, Eva Hadadi, Endre Kiss-Toth, Bernett Lee, Siew Cheng Wong, Ian Sudbery, Kajus Baidžajevas, Josephine Lum
Background and aims\ud \ud Lipid-rich foam cell macrophages drive atherosclerosis via several mechanisms, including inflammation, lipid uptake, lipid deposition and plaque vulnerability. The atheroma environment shapes macrophage function and phenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8926d7339edc8094e234150ed41ba4ff
Autor:
Wai Keung Chui, Muthukumar Karuppasamy, Eng-Hui Chew, Wei Hseun Yeap, Siew Cheng Wong, Ruirui Zhang, Waygene Seah, Hui-Li Ng, Eva Hadadi, Fei-Fei Gan, Siew-Min Ong
Publikováno v:
Food and Chemical Toxicology. 116:238-248
Chalcones present in edible plants possess anti-cancer and anti-inflammatory properties, with the Michael acceptor moiety reported to be responsible for their biological activities. In this study, two novel dihydrotriazine-chalcone compounds previous
Autor:
Truong-Minh Dang, Tze Pin Ng, Anis Larbi, Eva Hadadi, Crystal Tze Ying Tan, Siew-Min Ong, Siew Cheng Wong, Wei-Hseun Yeap
Publikováno v:
Cell Death and Disease, Vol 9, Iss 3, Pp 1-12 (2018)
Cell Death & Disease
Cell Death & Disease
Human primary monocytes comprise a heterogeneous population that can be classified into three subsets based on CD14 and CD16 expression: classical (CD14high/CD16−), intermediate (CD14high/CD16+), and non-classical (CD14low/CD16+). The non-classical
Publikováno v:
Redox Biology
Redox Biology, Vol 25, Iss, Pp-(2019)
Redox Biology, Vol 25, Iss, Pp-(2019)
Recent years have seen a renaissance in the research linking inflammation and cancer with immune cells playing a central role in smouldering inflammation in the tumor microenvironment. Diverse immune cell types infiltrate the tumor microenvironment,
Autor:
José M. Adrover, Subhra K. Biswas, Shu Zhen Chong, Jackson LiangYao Li, Anis Larbi, Zhiyong Poon, Etienne Becht, Shihui Foo, Goh Chi Ching, Ka Hang Liong, Hweixian Leong Penny, Florent Ginhoux, Maximilien Evrard, Je Lin Sieow, Karl Balabanian, Jia Wang Chua, Françoise Bachelerie, Vikas Madan, Andrés Hidalgo, I-hsin Su, William Hwang, Lai Guan Ng, Immanuel Kwok, Siew Cheng Wong, Karen Wei Weng Teng, Sapna Devi, Leonard Tan, Jinmiao Chen, H. Phillip Koeffler, Evan W. Newell
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Instituto de Salud Carlos III (ISCIII)
Neutrophils are specialized innate cells that require constant replenishment from proliferative bone marrow (BM) precursors as a result of their short half-life. Although it is established that neutrophils are derived from the granulocyte-macrophage
Publikováno v:
BioMed Research International, Vol 2014 (2014)
BioMed Research International
BioMed Research International
Parkinson’s disease (PD) is a chronic neurodegenerative disease underpinned by both genetic and environmental etiologic factors. Recent findings suggest that inflammation may be a pathogenic factor in the onset and progression of both familial and
Autor:
Siew Min Ong, Nurhashikin Yusof, Siew Cheng Wong, Wei Hseun Yeap, Olaf Rötzschke, Endre Kiss-Toth, Eva Hadadi, Biyan Zhang, Kajus Baidžajevas, Kia Joo Puan, Heather L. Wilson
Publikováno v:
Scientific Reports
Monocytes play a central role in regulating inflammation in response to infection or injury, and during auto-inflammatory diseases. Human blood contains classical, intermediate and non-classical monocyte subsets that each express characteristic patte