Zobrazeno 81 - 90
of 7 351
pro vyhledávání: '"11"'
Autor:
Xiaolin Luo, Carolyn Hernandez, Shuangwei Li, Kaisa L. Hanley, Rohit Loomba, Nazilla Alderson, Helen He Zhu, Jia Fan, Gen-Sheng Feng, Nissi Varki, Rui Liao, Xufu Wei, Catherine Chu, Shuang-Jian Qiu, Kirsten N. Malo
Publikováno v:
Cell reports, vol 17, iss 11
The complexity of liver tumorigenesis is underscored by the recently observed anti-oncogenic effects of oncoproteins, although the mechanisms are unclear. Shp2/Ptpn11 is a proto-oncogene in hematopoietic cells, and antagonizes the effect of tumor sup
Autor:
Angelique L.W.M.M. Rops, M.A.H. Bakker-van Bebber, Luuk B. Hilbrands, Martin Götte, M. Kouwenberg, J. van der Vlag, L.E. Diepeveen
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0230835 (2020)
PLoS One, 15, 7
PLoS One, 15
PLoS ONE
PLoS One, 15, 7
PLoS One, 15
PLoS ONE
Syndecan-1 (Sdc-1) is a heparan sulfate proteoglycan that can bind cytokines and chemokines via its heparan sulfate side chains, and has immunomodulatory properties in experimental models. Sdc-1 expression has been reported on dendritic cells (DC) an
Autor:
Huwart, Sabrina J. P.1 (AUTHOR), de Wouters d'Oplinter, Alice1 (AUTHOR), Rastelli, Marialetizia1 (AUTHOR), Van Hul, Matthias1 (AUTHOR), de Vos, Willem M.2,3 (AUTHOR), Luquet, Serge4 (AUTHOR), Cani, Patrice D.1 (AUTHOR), Everard, Amandine1 (AUTHOR) amandine.everard@uclouvain.be
Publikováno v:
Cells (2073-4409). Aug2022, Vol. 11 Issue 16, p2534. 19p.
Autor:
Ying Ying Tan, Brijesh V. Patel, Sanooj Soni, Rhodri Handslip, Cecilia M O'Kane, Rhianna F Baldi, Michael R Wilson, Miroslav Malesevic, Marissa Wen Koh, Daniel F. McAuley, Kieran P. O'Dea, Masao Takata
Publikováno v:
Am J Respir Crit Care Med
Koh, M W, Baldi, R F, Soni, S, Handslip, R, Tan, Y Y, O'Dea, K P, Malesevic, M, McAuley, D F, O'Kane, C M, Patel, B V, Takata, M & Wilson, M R 2021, ' Secreted Extracellular Cyclophilin A is a Novel Mediator of Ventilator Induced Lung Injury ', American Journal of Respiratory and Critical Care Medicine . https://doi.org/10.1164/rccm.202009-3545oc
American Journal of Respiratory and Critical Care Medicine
Koh, M W, Baldi, R F, Soni, S, Handslip, R, Tan, Y Y, O'Dea, K P, Malesevic, M, McAuley, D F, O'Kane, C M, Patel, B V, Takata, M & Wilson, M R 2021, ' Secreted Extracellular Cyclophilin A is a Novel Mediator of Ventilator Induced Lung Injury ', American Journal of Respiratory and Critical Care Medicine . https://doi.org/10.1164/rccm.202009-3545oc
American Journal of Respiratory and Critical Care Medicine
Rationale: Mechanical ventilation is a mainstay of intensive care but contributes to the mortality of patients through ventilator induced lung injury. Extracellular Cyclophilin A is an emerging inflammatory mediator and metalloproteinase inducer, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e24658c1e9fe6306dfecc334396c2a9
http://hdl.handle.net/10044/1/88395
http://hdl.handle.net/10044/1/88395
Autor:
Lin Wu, Varsha Raghavan, Henry H. Nguyen, Hao Xu, Kailin R. Mesa, Vasso Episkopou, Dan R. Littman
Publikováno v:
The Journal of experimental medicine. 218(11)
TGF-β signaling is fundamental for both Th17 and regulatory T (Treg) cell differentiation. However, these cells differ in requirements for downstream signaling components, such as SMAD effectors. To further characterize mechanisms that distinguish T
Autor:
C. Theocharous, Emily McGovern, Amany Zekry, Anita E. Raposo, J. Seet-Lee, Jason Behary, Geoffrey W. McCaughan, J. Beretov, Nadia M.L. Amorim, Lan Gong, Emad M. El-Omar, K. Liu, H. Zheng, J. Chen, M. T. Jackson
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-15 (2021)
BMC Microbiology
BMC Microbiology
Background Emerging evidence implicates the gut microbiome in liver inflammation and hepatocellular carcinoma (HCC) development. We aimed to characterize the temporal evolution of gut dysbiosis, in relation to the phenotype of systemic and hepatic in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b7efe6a3d5373209a3d676bd76f640
https://hdl.handle.net/10453/155230
https://hdl.handle.net/10453/155230
Autor:
Jiaqi Xu, Xue Zhang, Hongqiang Cheng, Dacheng Gong, Huilun Zhang, Yiqing Li, Pan Liu, Yuehai Ke, Yuefei Zhang, Wenjuan Li, Wenfang Zheng, Hui Zhou
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 5, Pp n/a-n/a (2021)
Journal of Extracellular Vesicles
Journal of Extracellular Vesicles
As novel mediators of cell‐to‐cell signalling, small extracellular vesicles (sEVs) play a critical role in physiological and pathophysiological processes. To date, the molecular mechanisms that support sEV generation are incompletely understood.
Autor:
Alberto Herrera, Xin Xia, Declan Doogan, Nicolette Pollock, Kai-Wen Huang, Stephanie Dorman, Jiehua Zhou, Nagy A. Habib, Mikael H. Sodergren, Haitang Li, Robert Habib, Vikash Reebye, David C. Blakey, Bruce H. Littman, John J. Rossi
Publikováno v:
Molecular Therapy
Excessive or inappropriate inflammatory responses can cause serious and even fatal diseases. The CCAAT/enhancer-binding protein alpha (CEBPA) gene encodes C/EBPα, a transcription factor that plays a fundamental role in controlling maturation of the
Autor:
Oka, Shunichi, Li, Xiaoyan, Sato, Fuyuki, Zhang, Fengzhu, Tewari, Nitesh, Kim, Il‐Shin, Zhong, Liangjun, Hamada, Nobushiro, Makishima, Makoto, Liu, Yi, Bhawal, Ujjal K.
Publikováno v:
Journal of Periodontal Research; Jun2021, Vol. 56 Issue 3, p492-500, 9p, 4 Color Photographs, 2 Black and White Photographs, 1 Diagram
Autor:
Matijs van Meurs, Adnan Aslan, Fransien van Dijk, Rik Mencke, Daniela Jou-Valencia, Peter Heeringa, Joost G. J. Hoenderop, Jan-Luuk Hillebrands, Jan G. Zijlstra, Grietje Molema, Eliane R. Popa, Jill Moser
Publikováno v:
Critical Care Medicine
Critical Care Medicine, 46(12), E1196-E1203. LIPPINCOTT WILLIAMS & WILKINS
Critical Care Medicine, 46, 12, pp. E1196-E1203
Critical Care Medicine, 46, E1196-E1203
Critical Care Medicine, 46(12), E1196-E1203. LIPPINCOTT WILLIAMS & WILKINS
Critical Care Medicine, 46, 12, pp. E1196-E1203
Critical Care Medicine, 46, E1196-E1203
Supplemental Digital Content is available in the text.
Objectives: To determine the applicability of recombinant Klotho to prevent inflammation and organ injury in sepsis in man and mice. Design: Prospective, clinical laboratory study using “w
Objectives: To determine the applicability of recombinant Klotho to prevent inflammation and organ injury in sepsis in man and mice. Design: Prospective, clinical laboratory study using “w