Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jia, Nan"'
Autor:
Yun-Peng Zhang, Yi-Shuan Li, Shu Chien, Run-Ze Tang, Wei Pang, Jing Zhou, Fang-Fang Yang, Juan-Juan Zhu, Dong Wang, Zhi-Tong Jiang, Jia-Nan Zhao, Chuan-Rong Zhao, Yiran Zhou, Xiaohong Wang, Weijuan Yao, Qinghua Cui
Publikováno v:
Proc Natl Acad Sci U S A
Vascular endothelial cells are exposed to shear stresses with disturbed vs. laminar flow patterns, which lead to proinflammatory vs. antiinflammatory phenotypes, respectively. Effective treatment against endothelial inflammation and the consequent at
Autor:
Tian Xing, Zhang Feng, Chao Li, Ya-Ru Yang, Ming-Ming Liu, Xin-Yun Fang, Yuan He, Fang Wang, Xiao-Yan He, Xiao-Guo Suo, Jia-Nan Wang, Juan Jin, Jun Li, Hongmei Zang, Xiao-Ming Meng, Xiang Zhong, Wei-Jian Ni, Yu-Ting Cai, Yu-hang Dong
Publikováno v:
Acta Pharmacol Sin
Stratifin (SFN) is a member of the 14-3-3 family of highly conserved soluble acidic proteins, which regulates a variety of cellular activities such as cell cycle, cell growth and development, cell survival and death, and gene transcription. Acute kid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ff2b02515db5cfe9d3bb466430dfdc
https://europepmc.org/articles/PMC8791945/
https://europepmc.org/articles/PMC8791945/
Autor:
Jia-gen Wen, Jun Li, Biao Wei, Yong-Gui Wu, Hai-Di Li, Li Gao, Qin Yang, Jia-Nan Wang, Xiao-Ming Meng, Qiu-Ying Ma, Ling Jiang, Xue-Qi Liu
Publikováno v:
The FASEB Journal. 33:3523-3535
MLKL is a central mediator for necroptosis. Its knockout significantly relieves acute kidney injury (AKI). However, its upstream regulatory mechanism in AKI has not been fully elucidated. We recently reviewed how microRNAs (miRNAs), a type of well-st
Autor:
Yao Zhang, Li Gao, Xiao-Ming Meng, Qin Yang, Jia-Nan Wang, Xiao-wei Hu, Yu-hang Dong, Hui-Yao Lan
Publikováno v:
Kidney Diseases, Pp 1-19 (2021)
Kidney Dis (Basel)
Kidney Dis (Basel)
Background: Transforming growth factor-β (TGF-β)/Smad signaling is the central mediator in renal fibrosis, yet its functional role in acute kidney injury (AKI) is not fully understood. Recent evidence showed that TGF-β/Smad3 may be involved in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba70e5b86321d9cbf2f78a329f7b40d9
https://www.karger.com/Article/FullText/512986
https://www.karger.com/Article/FullText/512986
Autor:
Fang Wang, Chao Li, Yu-Ting Cai, Juan Jin, Xue-Qi Liu, Biao Wei, Xiao-Ming Meng, Tian Xing, Ling Jiang, Hai-Yong Chen, Jia-gen Wen, Xin Chen, Xiao-Yan He, Qin Yang, Jia-Nan Wang, Taotao Ma, Li Gao, Jun Li, Chen Yang
Publikováno v:
Redox Biology
Redox Biology, Vol 32, Iss, Pp-(2020)
Redox Biology, Vol 32, Iss, Pp-(2020)
The incidence and severity of acute kidney injury (AKI) is increased yearly in diabetic patients. Although the mechanisms for this remain unclear, the prevention of AKI in diabetic nephropathy is feasible and of value. As we detected highly activatio
Autor:
Ling Jiang, Biao Wei, Xue-Qi Liu, Jun Li, Qiu-Ying Ma, Fan-rong Wu, Jia-gen Wen, Qin Yang, Luyu Zhou, Jia-Nan Wang, Tao tao Ma, Hai-Di Li, Li Gao, Xiao-Ming Meng
Publikováno v:
Free Radical Biology and Medicine. 124:466-472
Reactive oxygen species derived from NADPH oxidase contribute to a wide variety of renal diseases. Nox4, the major NADPH isoform in kidney, produces mainly H2O2 that regulates physiological functions. Nox4 contributes to redox processes involved in d
Autor:
Yu-hang Dong, Yong-Gui Wu, Yao Zhang, Jun Li, Jin-Fang Ge, Qin Yang, Jia-Nan Wang, Xiao-Ming Meng, Ju-tao Yu, Juan Jin, Hai-Di Li, Xiao-wei Hu, Hai-Yong Chen
Publikováno v:
Pharmacological Research. 163:105286
Alcohol consumption is one of the risk factors for kidney injury. The underlying mechanism of alcohol-induced kidney injury remains largely unknown. We previously found that the kidney in a mouse model of alcoholic kidney injury had severe inflammati
Autor:
Sai Zhu, Xiao-Feng Li, Xin Chen, Hai-Di Li, Fang-Tian Bu, Yu Chen, Cheng Huang, Si-Yu Chen, Jia-Nan Wang, Xue-Yin Pan, Jun Li
Publikováno v:
International Immunopharmacology. 76:105838
Hepatic fibrosis, a common pathological feature and leading cause of various chronic liver diseases, still lacks effective therapy. Hesperetin derivative (HD) is a derivative of Traditional Chinese Medicine monomer isolated from the fruit peel of Cit
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 117, Iss, Pp-(2019)
Atherosclerosis is initiated by the local inflammation response to lipid deposition, and the most commonly administered antiatherogenic drugs are statins. Based on traditional Chinese medicine (TCM) evidence, we aimed to find effective therapeutic ag
Autor:
Ling Jiang, Xiao-Ming Meng, Xue-Qi Liu, Zang Hongmei, Cheng Huang, Ming-Ming Liu, Biao Wei, Jun Li, Hai-Di Li, Gui-Ling Ren, Wei-Feng Wu, Qin Yang, Jia-Nan Wang, Qiu-Ying Ma, Li Gao, Cheng Jiang
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 98(7)
E-cadherin is a major component of tubular adherent proteins that maintain intercellular contacts and cell polarity in epithelial tissue. It is involved in pathological processes of renal cell carcinoma and fibrotic diseases via epithelial–mesenchy