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pro vyhledávání: '"Tohru Sugawara"'
Publikováno v:
STAR Protocols
Summary We recently demonstrated that the zygotic gene Zscan5b is involved in maintaining the genomic integrity of pluripotent stem cells (PSCs) during mitosis and that Zscan5b gene expression can prevent chromosomal abnormalities. Here, we provide a
Autor:
Justin K. Ichida, Jesse D. Lai, Gabriel R. Linares, Shu-Ting Hung, Tohru Sugawara, Shaoyu Lin, Gabriel Rocha, Yingxiao Shi, Kim A. Staats, Carina Seah, Michael Chickering, Yaoming Wang, Berislav V. Zlokovic, Abhay P. Sagare
Publikováno v:
JCI insight. 5
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease with diverse etiologies. Therefore, the identification of common disease mechanisms and therapeutics targeting these mechanisms could dramatically improve clinical outcomes. To this
Autor:
Tohru Sugawara1 (AUTHOR), Koichiro Nishino2 (AUTHOR), Akihiro Umezawa1 (AUTHOR), Hidenori Akutsu1 (AUTHOR) hakutsu@nch.go.jp
Publikováno v:
Stem Cell Research & Therapy. 2012, Vol. 3 Issue 2, p1-10. 10p. 2 Diagrams, 2 Charts.
Publikováno v:
Stem Cell Research & Therapy
Induced pluripotent stem (iPS) cells, obtained from reprogramming somatic cells by ectopic expression of a defined set of transcription factors or chemicals, are expected to be used as differentiated cells for drug screening or evaluations of drug to