Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Stephen Lee"'
Autor:
Miklós Péterfy, Sarada Charugundla, Peter Tontonoz, Wenchao Zhang, Stephen Lee, Alice Mouton, Diana M. Shih, Marcus M. Seldin, Aldons J. Lusis, Zhiqiang Zhou, Prashant Rajbhandari, Fangfei Guo, Matteo Pellegrini
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
Scientific Reports
Scientific reports, vol 11, iss 1
Scientific Reports
Scientific reports, vol 11, iss 1
We recently showed that NOTUM, a liver-secreted Wnt inhibitor, can acutely promote browning of white adipose. We now report studies of chronic overexpression of NOTUM in liver indicating that it protects against diet-induced obesity and improves gluc
Autor:
Jian Huang, Christophe Morisseau, Da Yong Hu, Bruce D. Hammock, Chang Bin Li, Ying Luo, Jun Yang, Kin Sing Stephen Lee, Xin Kang, Ai Peng, Jun-Yan Liu, Bingqing Deng, Mingyu Wu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 47
Acute kidney injury (AKI) causes severe morbidity and mortality for which new therapeutic strategies are needed. Docosahexaenoic acid (DHA), arachidonic acid (ARA), and their metabolites have various effects in kidney injury, but their molecular mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b29fc41fb2dd153bba1b23fde9c495
https://escholarship.org/uc/item/8kp598c4
https://escholarship.org/uc/item/8kp598c4
Autor:
Kin Sing Stephen Lee, Marcelo Henrique Napimoga, Bruce D. Hammock, Fawaz G. Haj, Donald A. Bruun, Bora Inceoglu, Carlos Antonio Trindade-da-Silva, Ahmed Bettaieb, Sumanta Kumar Goswami, Carlos Ueira-Vieira
Publikováno v:
The Journal of pharmacology and experimental therapeutics, vol 361, iss 3
Epoxyeicosatrienoic acids (EETs), metabolites of arachidonic acid derived from the cytochrome P450 enzymes, are mainly metabolized by soluble epoxide hydrolase (sEH) to their corresponding diols. EETs but not their diols, have anti-inflammatory prope
Autor:
Ebenezer N. Yamoah, Ning Li, Jun Yang, Sin Mei Ma, Victor C. Lau, Bruce D. Hammock, Javier E. López, Lianguo Wang, Ahmed Bettaieb, Crystal M. Ripplinger, Richard E. Myers, Xiao-Dong Zhang, Jeong-Han Lee, Demetria Su, Deborah K. Lieu, Padmini Sirish, Valeriy Timofeyev, Kin Sing Stephen Lee, Nipavan Chiamvimonvat, Fawaz G. Haj, J. Nilas Young
Publikováno v:
Circulation. Arrhythmia and electrophysiology, vol 9, iss 5
Background— Atrial fibrillation represents the most common arrhythmia leading to increased morbidity and mortality, yet, current treatment strategies have proven inadequate. Conventional treatment with antiarrhythmic drugs carries a high risk for p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337fd996e1d28ec44d82d36d9a140c03
https://europepmc.org/articles/PMC4869994/
https://europepmc.org/articles/PMC4869994/
Autor:
Xiaohui Wu, Anna C. Calkin, Aldons J. Lusis, Stephen Lee, Peter Tontonoz, Caroline M. W. van Stijn, Rajendra I. Tangirala, Jason K. Kim, Cynthia Hong
Publikováno v:
Circulation research, vol 115, iss 4
Rationale : The E3 ubiquitin ligase inducible degrader of the low-density lipoprotein receptor (IDOL) triggers lysosomal degradation of the low-density lipoprotein receptor. The tissue-specific effects of the IDOL pathway on plasma cholesterol and at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc0d314b2aafca5a97b9f3ae3b1b5d2
https://escholarship.org/uc/item/2276h79m
https://escholarship.org/uc/item/2276h79m