Zobrazeno 1 - 2
of 2
pro vyhledávání: '"John Meekin"'
Autor:
Krista Kinneer, Michael J. Wick, David A. Tice, John Meekin, Sriram Sridhar, Marlon Rebelatto, Alyssa Moriarty, Yu-Tzu Tai, Kenneth C. Anderson, Arnaud C. Tiberghien, Stephen J. Gregson, Christine Kiefer, Ronald Herbst, Sandrina Phipps, Luke Masterson, Philip Howard, Nazzareno Dimasi, Kyriakos P. Papadopoulos
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 24(24)
Purpose: Antibody–drug conjugates (ADC) utilizing noncleavable linker drugs have been approved for clinical use, and several are in development targeting solid and hematologic malignancies including multiple myeloma. Currently, there are no reliabl
Autor:
Sandrina Phipps, Philip Howard, Binyam Bezabeh, Nazzareno Dimasi, Michael J. Wick, Christine Kiefer, Ronald Herbst, Alyssa Moriarty, Luke Masterson, Megan Groves, Ryan Fleming, David A. Tice, Arnaud C. Tiberghien, Marlon Rebelatto, John Meekin, Krista Kinneer
Publikováno v:
Molecular Cancer Therapeutics. 17:A138-A138
Antibody-drug conjugates (ADCs) combine a monoclonal antibody with a potent cytotoxic drug to preferentially eliminate antigen-positive cells for the treatment of cancer. ADCs bearing non-cleavable warheads such as the pyrrolobenzodiazepine (PBD) SG3