Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Richard A, Koup"'
Publikováno v:
Annual Review of Medicine. 60:471-484
There is an intense interplay between HIV and the immune system, and the literature is replete with studies describing various immunological phenomena associated with HIV infection. By definition, HIV is the cause of the immunologic findings, for wit
Autor:
Douglas D. Richman, Michael Kilby, John W. Mellors, Marty Markowitz, Susan J. Little, Jeannette M. Whitcomb, Eric S. Daar, Richard A. Koup, Jean-Pierre Routy, Elizabeth Connick, Brian Conway, Lei Wang, Ann C. Collier, Nicholas S. Hellmann, Sarah Holte
Publikováno v:
New England Journal of Medicine. 347:385-394
Among persons in North America who are newly infected with the human immunodeficiency virus (HIV), the prevalence of transmitted resistance to antiretroviral drugs has been estimated at 1 to 11 percent.We performed a retrospective analysis of suscept
Autor:
James I. Mullins, Jia Qi Zhao, Lisa M. Frenkel, Raymond J. Apple, Steven M. Wolinsky, Ashley T. Haase, Gerald H. Learn, Irvin S. Y. Chen, Abdallah Harmache, Laura Manns-Arcuino, Xi C. He, Anup Madan, Donald M. Thea, Norbert J. Roberts, Richard A. Koup, Paul Krogstad, Bette T. Korber, Leroy Hood, Katherine Staskus, Belinda L. Herring, Richard W. Steketee, Mary Zupancic, Robert W. Coombs, David D. Ho, Joan E. Nichols, Marcia L. Kalish, Shan-Lu Liu, David Muthui, Savita Pahwa
Publikováno v:
Science. 280:1073-1077
Detection of human immunodeficiency virus–type 1 (HIV-1) on only one or a few occasions in infants born to infected mothers has been interpreted to indicate that infection may be transient rather than persistent. Forty-two cases of suspected transi
Autor:
Richard A. Koup, Tse Wen Chang, Michael S. C. Fung, William N.C. Sun, Jeffrey T. Safrit, Charla Andrews, Dietmar G. Braun
Publikováno v:
AIDS. 7:15-22
To determine whether passive transfer of a monoclonal antibody specific for the principal neutralizing determinant in the V3 region of HIV-1IIIB gp120 can protect mice with severe combined immunodeficiency (SCID) transplanted with normal human periph
Autor:
Riyaz S. Mehta, David Price, Rachel E. Hewitt, Richard A. Koup, Michael K. Racke, Peter Stastny, Michael P. Crawford, Shirley Yan, Daniel C. Douek, Sterling B. Ortega, Nitin J. Karandikar
Publikováno v:
Blood. 103(11)
Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous system (CNS) with features suggestive of T-cell-mediated pathology. Most prior reports have focused on CD4+ T cells with the underlying assumption that MS is pre
Autor:
Mark B. Feinberg, Harold M. McClure, Donald L. Sodora, Silvija I. Staprans, Guido Silvestri, Mirko Paiardini, Richard A. Koup, Shawn P. O'Neil
Publikováno v:
Immunity. 18(3)
HIV-infected humans and SIV-infected rhesus macaques who remain healthy despite long-term infection exhibit exceptionally low levels of virus replication and active antiviral cellular immune responses. In contrast, sooty mangabey monkeys that represe
Autor:
Mark Dybul, David Price, Brenna J. Hill, Joseph P. Casazza, Richard A. Koup, Mark Connors, Daniel C. Douek, Steven M. Wolinsky, Yukari Okamoto, Michael R. Betts, David R. Ambrozak, Zvi Grossman, Kevin J. Kunstman, Annette Oxenius, Janaki Kuruppu, Jason M. Brenchley
Publikováno v:
Nature. 417(6884)
HIV infection is associated with the progressive loss of CD4(+) T cells through their destruction or decreased production. A central, yet unresolved issue of HIV disease is the mechanism for this loss, and in particular whether HIV-specific CD4(+) T
Autor:
Steven M. Wolinsky, Sebastian Bonhoeffer, Maarten C. Boerlijst, Roy M. Anderson, Jeffrey T. Safrit, Richard A. Koup, Avidan U. Neumann, Kevin J. Kunstman, Robert M. May, Andrew J. McMichael, Martin A. Nowak, Bette T. Korber
Publikováno v:
Science (New York, N.Y.). 274(5289)
Autor:
Richard A. Koup, David D. Ho
Publikováno v:
AIDS. 5:1263-1264