Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rodrigo Matus-Nicodemos"'
Autor:
Stefano Vavassori, Karnail Singh, Valentina Marcelli, Rodrigo Matus-Nicodemos, Moraima Castro-Faix, Anibal Valentin-Acevedo, Lori R. Covey
Publikováno v:
The Journal of Immunology. 186:2164-2171
CD40L (CD154) is regulated at the posttranscriptional level by an activation-induced process that results in a highly stable transcript at extended times of T cell activation. Transcript stability is mediated by polypyrimidine tract-binding protein (
Autor:
Frank L. Sinquett, Sanaz Oghlidos, Valentina Marcelli, Lori R. Covey, Joseph F. Porter, Rodrigo Matus-Nicodemos, Jennifer Laughlin
Publikováno v:
Immunology. 124:368-379
Summary We previously identified a cis-acting element within the 3′ untranslated region of CD40 ligand messenger RNA (mRNA) that is composed of three complex binding sites and acts to increase mRNA stability in both in vitro and in vivo systems. We
Autor:
Madhu Prabhakaran, Masaru Kanekiyo, Daniel Lingwood, Adam K. Wheatley, Sandeep Narpala, Rodrigo Matus-Nicodemos, James R R Whittle, Barney S. Graham, Gary J. Nabel, Adrian B. McDermott, Hadi M. Yassine, Julie E. Ledgerwood, Richard A. Koup, Robert T. Bailer, Steven S. Ma
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 195(2)
Because of significant viral diversity, vaccines that elicit durable and broad protection against influenza have been elusive. Recent research has focused on the potential of highly conserved regions of the viral hemagglutinin (HA) as targets for bro
Publikováno v:
The Journal of Immunology. 194:61.18-61.18
We have previously shown that the RNA binding protein, polypyrimidine tract-binding protein (PTB) plays a crucial role in regulating the expression of CD40L in activated CD4 T cells. Regulation occurs through stabilizing the message at late times of
Publikováno v:
The Journal of Immunology. 186:109.15-109.15
The expression of the CD40 ligand (CD40L) is controlled at the posttranscriptional level by an activation-induced program of regulated mRNA stability whereby at early times of activation the mRNA is highly unstable and at later times (24-48 hr) the t
Publikováno v:
The Journal of Immunology. 184:51.8-51.8
The expression of CD40L is tightly regulated at the posttranscriptional level throughout a time course of T cell activation, which corresponds to a significant increase in message stability at late times of activation (24-48 hr). Previous work reveal