Zobrazeno 11 - 13
of 13
pro vyhledávání: '"Mariano Severgnini"'
Autor:
Limor Cohen, Cloud P. Paweletz, Biagio Ricciuti, Anika E. Adeni, David R. Walt, Julianna Supplee, Reiko Nishihara, Pasi A. Jänne, Padric M. Garden, Mariano Severgnini, Alissa Keegan, Mark M. Awad
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundBlood-based biomarkers of anti-solid tumor immune checkpoint blockade (ICB) response are lacking. We hypothesized that changes in systemic cytokine levels with the initial doses of programmed cell death protein 1 (PD-1) pathway inhibitors w
Autor:
Danielle N. Margalit, F. Stephen Hodi, Robert I. Haddad, Roy B. Tishler, Mariano Severgnini, Jonathan D. Schoenfeld, Vishwajith Sridharan, Stephanie A. Lynch
Publikováno v:
Journal for Immunotherapy of Cancer
Background Preclinical studies suggest a synergistic effect between radiation, immunotherapy and anti-angiogenic therapy, although the mechanisms are unclear. Angiogenic cytokines are known to affect the immune system, and their levels may be associa
Autor:
Amy Simon, Mariano Severgnini, Thomas J. Mariani, Lauren Cohn, Marina C. Simeone-Penney, Robert J. Homer, Powen Tu
Publikováno v:
The Journal of Immunology. 178:6191-6199
The STAT3 transcription factor is critical for cytokine signaling and the acute phase response, but its role in allergic asthma is largely undefined. To investigate the role of STAT3 in mediating allergic inflammation, we used chemical and genetic ap
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