Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Justin Komguep Nono"'
Autor:
Simphiwe Simelane, Harukazu Suzuki, Suraj P. Parihar, Mumin Ozturk, Justin Komguep Nono, Thabo Mpotje, Sugata Roy, Shandre Pillay, Shelby-Sara Jones, Sibongiseni K L Poswayo, Julius Ebua Chia, Frank Brombacher, Reto Guler, Lerato Hlaka
Publikováno v:
The Journal of Infectious Diseases
Background Interleukin 4 (IL-4i1)–induced gene 1 encodes L-phenylalanine oxidase that catabolizes phenylalanine into phenylpyruvate. IL-4i1 is mainly expressed by antigen-presenting cells (APCs), inhibits T-cell proliferation, regulates B-cell acti
Autor:
Justin Komguep Nono, Thabo Mpotje, Paballo Mosala, Nada Abdel Aziz, Fungai Musaigwa, Lerato Hlaka, Thomas Spangenberg, Frank Brombacher
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Beyond transient control of the infection, additional benefits of mass drug administration of praziquantel in endemic communities have been suggested in communities but not mechanistically investigated experimentally. The present study sought to eval
Autor:
Thomas J. Scriba, Daniel E. Zak, Julius Ebua Chia, Harukazu Suzuki, Suraj P. Parihar, Reto Guler, Adam Penn-Nicholson, Lerato Hlaka, Sugata Roy, Mumin Ozturk, Nada Abdel Aziz, Thabo Mpotje, Willem A. Hanekom, Santosh Kumar, Justin Komguep Nono, Frank Brombacher
Publikováno v:
Mucosal Immunology
SUMMARY Basic leucine zipper transcription factor 2 (Batf2) activation is detrimental in Type 1-controlled infectious diseases, demonstrated during infection with Mycobacterium tuberculosis (Mtb) and Listeria monocytogenes Lm. In Batf2-deficient mice
Publikováno v:
Journal of Leukocyte Biology
Development of IL-4 receptor alpha (IL-4Rα)-dependent cellular immunity regulates host protection against acute schistosomiasis. In this study, we investigated the importance of IL-4Rα-expressing CD11c+ cells in driving the development of optimal c
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Background Alveolar echinococcosis (AE), caused by the metacestode larval stage of the fox-tapeworm Echinococcus multilocularis, is a chronic zoonosis associated with significant modulation of the host immune response. A role of regulatory T-cells (T
Autor:
Severin Donald Kamdem, Francis Konhawa, Erve Martial Kuemkon, Leonel Meyo Kamguia, Gladys K. Tchanana, Frungwa Nche, Alim Oumarou, Mamadou Hamza, Yasmine Ouratou, Mariette Nzoku Tcheutchoua, René Ghislain Essomba, Marie Paule Ngogang, Michel Kengne, Palmer Masumbe Netongo, Bienvenu Etogo Ondigui, Marie Claire Okomo Assoumou, Frank Brombacher, Justin Komguep Nono
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology
Background: This study aimed to investigate the association of plasma levels of IL-33, a mucosal alarmin known to elicit type-2 immunity, with infection and liver fibrosis profiles of school children from an endemic area for Schistosoma mansoni, mala
Autor:
Keisha S De Gouveia, Jacqueline S. Womersley, Ousman Tamgue, Tiroyaone M Brombacher, Nokuthula Makena, Frank Brombacher, Matthew Darby, Justin Komguep Nono
Publikováno v:
The Journal of Immunology. 198:2681-2688
The role of proinflammatory cytokines in cognitive function has been investigated with both beneficial and possible detrimental effects, depending on the cytokine. More recently, the type 2 IL-4 has been demonstrated to play a role in cognition. In t
Autor:
Hlumani Ndlovu, Justin Komguep Nono, Nada Abdel Aziz, Natalie Eva Nieuwenhuizen, Frank Brombacher
Publikováno v:
Frontiers in immunology
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Schistosomiasis (bilharzia) is a parasitic helminth disease that can cause severe inflammatory pathology leading to organ damage in humans. Failure of the host to regulate egg-driven granulomatous inflammation causes host morbidity during chronic inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55df9bea8429d58422839123059b4a48
https://hdl.handle.net/21.11116/0000-0004-0172-A21.11116/0000-0004-0174-8
https://hdl.handle.net/21.11116/0000-0004-0172-A21.11116/0000-0004-0174-8
Autor:
Justin Komguep Nono, Severin Donald Kamdem, Palmer Masumbe Netongo, Smritee Dabee, Michael Schomaker, Alim Oumarou, Frank Brombacher, Roger Moyou-Somo
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology
Background and Methods: Schistosomiasis is debilitating and reported to impair immune responsiveness of infected hosts. In Cameroon, mass drug administration (MDA) is used in schoolchildren to reduce transmission of S. haematobium and S. mansoni. The
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, Vol 9 (2018)
Liver fibrosis is a wound-healing process purposely aimed at restoring organ integrity after severe injury caused by autoimmune reactions, mechanical stress or infections. The uncontrolled solicitation of this process is pathogenic and a pathognomoni