Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Julia Jellusova"'
Autor:
Julia Jellusova
Publikováno v:
Nature Immunology. 24:893-894
Autor:
Julia Jellusova, Ellen McAllister
Publikováno v:
Current Opinion in Immunology. 71:69-74
BAFF is an essential cytokine primarily known for its role in maintaining B cell homeostasis via induction of a pro-survival gene expression profile. Additionally, recent evidence suggests that BAFF induced signaling also drives a metabolic program t
Publikováno v:
Current Opinion in Immunology. 71:vii-ix
Autor:
Julia Jellusova
Publikováno v:
Immunological reviewsREFERENCES. 295(1)
In response to mitogenic stimulation, B cells activate different pro-anabolic signaling pathways such as c-Myc- and mTORC1-dependent networks to satisfy the energetic demands of biomass synthesis and proliferation. In order to preserve viability and
Publikováno v:
The Journal of Immunology. 199:2998-3003
B cells contribute critically to an effective immune response by producing antigen-specific antibodies. During the immune response to so-called thymus dependent antigens, activated B cells seek T cell help and form germinal centers. In contrast, thym
Autor:
Matthew H. Cato, Parham Ramezani-Rad, James R. Woodgett, John R Apgar, Cindi Chen, Robert J. Benschop, Julia Jellusova, Adam D. Richardson, Robert C. Rickert, Elaine M Conner, Charlotte R Leung
Publikováno v:
Nature immunology
B cells predominate in a quiescent state until an antigen is encountered, which results in rapid growth, proliferation and differentiation of the B cells. These distinct cell states are probably accompanied by differing metabolic needs, yet little is
Autor:
Julia Jellusova
Publikováno v:
Immunology letters. 201
Mounting evidence demonstrates that specific metabolic adaptations are needed to support B cell development and differentiation and to enable B cells to thrive in different environments. Mitogen induced activation of intracellular signaling pathways
Autor:
Joachim Gläsner, André Gessner, Selina Sitte, Ruggero Pardi, Florian Weisel, Julia Jellusova, Martina Panattoni
Publikováno v:
The Journal of Immunology. 188:2677-2686
Jun activation domain-binding protein 1 (JAB1) regulates ubiquitin-dependent protein degradation by deneddylation of cullin-based ubiquitin ligases and, therefore, plays a central role in regulating proliferation and apoptosis. Because these processe
Autor:
Julia Jellusova, Edward M. Conway, Ana V. Miletic, G. V. Baracho, Charlotte R. Lee, Robert C. Rickert, Matthew H. Cato
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 196(5)
Survivin is a member of the inhibitor of apoptosis family of proteins and a biomarker of poor prognosis in aggressive B cell non-Hodgkin’s lymphoma. In addition to its role in inhibition of apoptosis, survivin also regulates mitosis. In this articl
Autor:
Julia Jellusova, Matthew H. Cato, Irene W. Yau, Robert C. Rickert, Tatiana Hurtado de Mendoza, Robert Brink
In the secondary lymphoid organs, intimate contact with follicular dendritic cells (FDCs) is required for B cell retention and Ag-driven selection during the germinal center response. However, selection of self-reactive B cells by Ag on FDCs has not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d08817add2879979d50ce6952824bf45
https://europepmc.org/articles/PMC3766769/
https://europepmc.org/articles/PMC3766769/