Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Ye Zheng"'
Autor:
Zhe Li, Xirun Zheng, Zecheng Yu, Bin Wu, Xinmin Qiu, Mingbang Wang, Xiaodong Luo, Wai Sang Poon, Chunying Zheng, Xianwei Su, Zhuo Li, Yuzhen Fan, Weiwei Chen, Yan Zeng, Qiaodi Cai, Enli Luo, Jianwen Guo, Qiao-Zhen Su, Wai-Yee Chan, Chun-Ye Zheng, Yingjun Chen, Gang Lu, Yanjuan Xu, Xinjie Chen, Zhangyong Xia
Publikováno v:
Neuroscience. 480:65-78
Parkinson's disease (PD) is the second most frequently diagnosed neurodegenerative disease. The purpose of this study was to investigate the link between microbiota composition in important mucosal interfaces (oral, nasal, and intestinal) and PD. Seq
Publikováno v:
Nat Immunol
Maintenance of tissue homeostasis is dependent on the communication between stem cells and supporting cells in the same niche. Regulatory T cells (Treg) are a critical component of the stem cell niche to support their differentiation. How Treg cells
Autor:
Bin Li, Wen-Xuan Sun, Wan-Ying Zhang, Ye Zheng, Lu Qiao, Yue-Ming Hu, Wei-Qiang Li, Di Liu, Bing Leng, Jia-Ren Liu, Xiao-Feng Jiang, Yan Zhang
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 12 (2021)
Frontiers in Genetics, Vol 12 (2021)
Rationale: Severe asthma is a heterogeneous disease with multiple molecular mechanisms. Gene expression studies of asthmatic bronchial epithelial cells have provided biological insights and underscored possible pathological mechanisms; however, the m
Publikováno v:
The Journal of Immunology. 208:167.10-167.10
The maintenance of tissue homeostasis in steady state or under stress is dependent on the proper communication between the stem cells and the supporting cells in their microenvironment or “niche”. In addition to promoting immune tolerance, regula
Autor:
Sela T. Po'uha, Francesca Walker, Ian P. Street, Jamie I. Fletcher, Janet Weinstock, Meng Xiao Luo, Jayne Murray, Marie Liesse Asselin-Labat, Kristy Shield-Artin, Ye Zheng, Clare E. Weeden, Alvin Kamili, Anderly C. Chueh, Chin Wee Tan, Gregor Ebert, Mark G. Devlin, Maree C. Faux, Clare L. Scott, Michelle Haber, Helen Witchard, Esmee Broekhuizen, Matthew Wakefield, Nadia J. Kershaw, Jane E. Visvader, Serena R Kane, Geoffrey J. Lindeman, Judy Doherty, Susan A. Charman, Antony W. Burgess, Maria Kavallaris, François Vaillant, Keith G. Watson, Christoph Grohmann, Gwo-Yaw Ho, Guillaume Lessene
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 3, Pp 1-18 (2021)
Cell Death and Disease, Vol 12, Iss 3, Pp 1-18 (2021)
Targeting cell division by chemotherapy is a highly effective strategy to treat a wide range of cancers. However, there are limitations of many standard-of-care chemotherapies: undesirable drug toxicity, side-effects, resistance and high cost. New sm
Autor:
Rebecca S. LaRue, Louisa E. Sjaastad, Mark S. Anderson, Calvin B. Williams, Praful Aggarwal, Maria-Luisa Alegre, Ulrich Broeckel, Shawn A. Mahmud, Irina Proekt, Dimitre R. Simeonov, Jason B. Williams, Michael A. Farrar, Weishan Huang, Jonathan C. Jeschke, Corey N. Miller, Roland Ruscher, David L. Owen, Christine Henzler, Justin A. Spanier, Can Hekim, Avery August, Alexander Marson, Ye Zheng
Publikováno v:
Nature immunology
The developmental programs that generate a broad repertoire of regulatory T cells (Treg cells) able to respond to both self antigens and non-self antigens remain unclear. Here we found that mature Treg cells were generated through two distinct develo
Autor:
Alexandre V. Hirayama, Raphael Gottardo, Delaney R. Kirchmeier, Mark R. Dowling, Jordan Gauthier, David G. Maloney, Ye Zheng, Alyssa Sheih, Cameron J. Turtle, Abby W. Chucka, Tinh-Doan Phi
Publikováno v:
Blood. 138:1749-1749
Introduction Lymphodepletion chemotherapy followed by infusion of autologous T cells engineered to express a CD19-targeted chimeric antigen receptor (CAR) has shown high response rates in relapsed or refractory high-risk chronic lymphocytic leukemia
Autor:
Jovylyn Gatchalian, Chin-San Loo, Bhargav Venkatraghavan, Yuqiong Liang, Josephine Ho, Ye Zheng, Diana C. Hargreaves, Mingjun Xie, Mathias Leblanc
Publikováno v:
Immunity
Summary Regulatory T (Treg) cells play a pivotal role in suppressing auto-reactive T cells and maintaining immune homeostasis. Treg cell development and function are dependent on the transcription factor Foxp3. Here, we performed a genome-wide CRISPR
Autor:
Christina Chang, Ronald M. Evans, Nanhai He, Darryl J. Mar, Eun Jung Choi, Ruth T. Yu, Yuqiong Liang, Sagar P. Bapat, Christopher Liddle, Ian Vogel, Inkyu Lee, Michael Downes, Laura E. Crotty Alexander, Carmen Zhou, K. Mark Ansel, Sihao Liu, Jae Myoung Suh, Annette R. Atkins, Ye Zheng, Ling-juan Zhang, Richard L. Gallo, Alexander Marson
How obesity affects immune function is not well understood. Clinically, obesity is strongly associated with severe TH2 immunopathology1-3, though the physiological, cellular, and molecular underpinnings of this association remain obscure. Here, we de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9217f5acf2bd41a371301d3893e633a3
https://doi.org/10.1101/825836
https://doi.org/10.1101/825836
Autor:
Ye Zheng
Publikováno v:
Immunity. 47:211-214
Hayatsu et al. (2017) reveal that a FOXP3 mutant found in some patients afflicted with the autoimmune disease IPEX has broadened DNA-recognition specificity, directly repressing the expression of the gene encoding the transcription factor Batf. Their