Zobrazeno 21 - 30
of 49
pro vyhledávání: '"Ye Zheng"'
Autor:
Jovan Shepherd, Yi Liu, Ye Zheng, Christian J. Maine, Guo Fu, Mohsen Sabouri-Ghomi, Changchun Xiao, Nengming Xiao, Seung Goo Kang, Cheng-Jang Wu, Shunbin Xu, Alicia Gonzalez-Martin, Li-Fan Lu, Zhe Huang, Wen Hsien Liu, Alexander Hoffmann, Hyun Yong Jin
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
The Journal of Experimental Medicine
The Journal of experimental medicine, vol 213, iss 9
instname
The Journal of Experimental Medicine
The Journal of experimental medicine, vol 213, iss 9
Xiao and collaborators show that miR-155 regulates T follicular helper cell development and function by suppressing the E3 ubiquitin ligase Peli1.
MicroRNA (miRNA) deficiency impairs the generation of T follicular helper (Tfh) cells, but the con
MicroRNA (miRNA) deficiency impairs the generation of T follicular helper (Tfh) cells, but the con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa5ed3a272de3dc5bb9fdbe6d6cbcd4
http://hdl.handle.net/10486/685850
http://hdl.handle.net/10486/685850
Autor:
Lauren A. Mack, Christopher Liddle, Sigal Gery, Zhengshan Chen, Qi Cao, Henry Yang, Xianping Shi, Xuan Zhao, Haibo Sun, De-Chen Lin, Qi Chen, Jonathan W. Said, Serhan Alkan, Jing-Wen Bai, Ruishu Deng, Ling Wa Chong, Markus Müschen, Michael Downes, Ronald M. Evans, Jian-Jun Xie, Han Cho, Ruth T. Yu, Annette R. Atkins, Ye Zheng, Quan Zhen Li, H. Phillip Koeffler
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 47
The circadian system regulates numerous physiological processes including immune responses. Here, we show that mice deficient of the circadian clock genes Cry1 and Cry2 [Cry double knockout (DKO)] develop an autoimmune phenotype including high serum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec83e67eefb01b297a9051e42544974f
https://escholarship.org/uc/item/6wn972xv
https://escholarship.org/uc/item/6wn972xv
Autor:
Johan Auwerx, Ying Cui, Ruth T. Yu, Ronald M. Evans, Jianrong Wang, Hui Xiao, Caroline Zhang, Shuo Zhang, Annette R. Atkins, Ye Zheng, Na Zhang, Ruihong Zhu, Nanhai He, Michael Downes, Dexian Quan, Christopher Liddle, Qibin Leng, Chunhui Yang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
Nature Communications
Thymocytes must pass both positive and negative selections to become mature T cells. Negative selection purges thymocytes whose T-cell receptors (TCR) exhibit high affinity to self-peptide MHC complexes (self pMHC) to avoid autoimmune diseases, while
Autor:
Chin San Loo, Ye Zheng
Publikováno v:
The Journal of Immunology. 202:128.1-128.1
Forkhead box P3 (Foxp3) is an indispensable transcription factor that controls the development of regulatory T cells (Tregs) and programs their suppressive functions. Understanding the mechanisms that regulate Foxp3 expression can potentially lead to
Autor:
Tissa Hata, Xu Chen, Christian F. Guerrero-Juarez, Marc C. Liggins, Stella X. Chen, Yuqiong Liang, Ye Zheng, Min Li, Ling-juan Zhang, Richard L. Gallo, Maksim V. Plikus, Yun Tong, Fengwu Li, Hao Chen
Publikováno v:
Immunity. 50:121-136.e5
Dermal fibroblasts (dFBs) resist infection by locally differentiating into adipocytes and producing cathelicidin antimicrobial peptide in response to Staphylococcus aureus (S. aureus). Here, we show that neonatal skin was enriched with adipogenic dFB
Autor:
Nobuyuki Tanimura, Joshua J. Coon, Miao Cao, Sunduz Keles, Peiman Hematti, Ruiqi Liao, Yuannyu Zhang, Gary M. Wilson, Jian Xu, Xin Liu, Matthew R. Dent, Judith N. Burstyn, Ye Zheng, Emery H. Bresnick
Publikováno v:
Blood. 132:500-500
By functioning as an enzyme cofactor, hemoglobin component and gene regulator, heme is vital for life. One mode of heme-regulated transcription involves amplifying the activity of GATA-1, a key determinant of erythrocyte differentiation. To discover
Autor:
Takatoshi Chinen, Alexander Y. Rudensky, Rachel E. Niec, Dale T. Umetsu, Ye Zheng, Piper M. Treuting, Steven Z. Josefowicz, Hye Young Kim
Publikováno v:
Nature. 482:395-399
A balance between pro- and anti-inflammatory mechanisms at mucosal interfaces, which are sites of constitutive exposure to microbes and non-microbial foreign substances, allows for efficient protection against pathogens yet prevents adverse inflammat
Autor:
Nidhanjali Bansal, Christina Chang, Yuqiong Liang, Eleen Y. Shum, Jody C. Martin, James Ghadiali, Devon Jensen, Jing Hu, David Rosenfeld, Ye Zheng, H. Christina Fan
Publikováno v:
The Journal of Immunology. 200:120.11-120.11
Diverse immune populations reside in non-lymphoid organs and contribute to immune defense and tissue homeostasis. However, these cells are often hard to study due to low cell abundance and high heterogeneity. Recent advancements in single-cell sequen
Autor:
Ye Zheng, Alexander Y. Rudensky
Publikováno v:
Nature Immunology. 8:457-462
Foxp3, an X chromosome-encoded forkhead transcription factor family member, is indispensable for the differentiation of regulatory T cells. These cells have a vital role in preventing autoimmunity and pathology inflicted by uncontrolled immune respon
Publikováno v:
Nature Immunology. 7:401-410
The relationship between the T cell receptor (TCR) repertoires used by self-reactive transcription factor Foxp3-positive (Foxp3(+)) CD4(+) regulatory T cells (T(reg) cells) and nonregulatory T cells with autoimmune potential is unclear. Here we found