Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Terri D. Lyddon"'
Autor:
Mary LePique, Maddie Graham, Reinier Suarez, Clifton L. Ricana, Marc C. Johnson, Carolyn A. Robinson, Detlef Ritter, Terri D. Lyddon, Braxton Salcedo
Publikováno v:
Journal of Virology
In work with pathogenic viruses, it is useful to have rapid quantitative tests for viral infectivity that can be performed without strict biocontainment restrictions. A common way of accomplishing this is to generate viral pseudoparticles that contai
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008646 (2020)
PLoS Pathogens
PLoS Pathogens
Inositol hexakisphosphate (IP6) potently stimulates HIV-1 particle assembly in vitro and infectious particle production in vivo. However, knockout cells lacking inositol-pentakisphosphate 2-kinase (IPPK-KO), the enzyme that produces IP6 by phosphoryl
Autor:
Robert A. Dick, Clifton L. Ricana, John A. G. Briggs, Arianna M. Broad, Marc C. Johnson, J. Ryan Feathers, Florian K. M. Schur, Volker M. Vogt, Vladyslav Kravchuk, Chaoyi Xu, Juan R. Perilla, Dustin R. Morado, Terri D. Lyddon
Publikováno v:
PLoS Pathogens, Vol 16, Iss 1, p e1008277 (2020)
PLoS Pathogens
PLOS Pathogens
PLoS Pathogens
PLOS Pathogens
Retrovirus assembly is driven by the multidomain structural protein Gag. Interactions between the capsid domains (CA) of Gag result in Gag multimerization, leading to an immature virus particle that is formed by a protein lattice based on dimeric, tr
Publikováno v:
Journal of Virology. 87:1518-1527
Retroviruses, like all enveloped viruses, must incorporate viral glycoproteins to form infectious particles. Interactions between the glycoprotein cytoplasmic tail and the matrix domain of Gag are thought to direct recruitment of glycoproteins to nat
Publikováno v:
Journal of Virology. 86:4696-4700
We analyzed the nuclear trafficking ability of Gag proteins from six retroviral genera. Contrary to a previous report, human immunodeficiency virus type 1 (HIV-1) Gag showed no propensity to cycle through the nucleus. The only Gag protein that displa
Publikováno v:
American Journal of Reproductive Immunology. 52:67-73
Problem: Are toll-like receptors (TLRs) expressed by human endometrium and endometrial cell lines? Methods of study: Expression of each TLR mRNA species was determined by reverse transcriptase-polymerase chain reaction (RT-PCR) analysis of proliferat
Publikováno v:
Journal of virology. 84(6)
The Env protein from gibbon ape leukemia virus (GaLV) has been shown to be incompatible with human immunodeficiency virus type 1 (HIV-1) in the production of infectious pseudotyped particles. This incompatibility has been mapped to the C-terminal cyt
Autor:
Rebecca L. Jorgenson, Michael L. Misfeldt, Steven L. Young, Terri D. Lyddon, Margaret J. Lesmeister
Publikováno v:
Human immunology. 66(5)
Toll-like receptor 3 (TLR3) responds to dsRNA, a product of most viral life cycles, and initiates production of proinflammatory and antiviral cytokines. The role of TLR3 in human mucosal immunity of the endometrium has not been examined. The effects