Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sushanth Gouni"'
Autor:
Misha Hawkins, Nathan Fowler, Sandra B. Horowitz, Sushanth Gouni, Yago Nieto, Christopher R. Flowers, Jason R. Westin, Loretta J. Nastoupil, Raphael E Steiner, Haleigh Mistry, Michael R. Green, Paolo Strati, Luis Fayad, Simrit Parmar, Lei Feng, Swaminathan P. Iyer, Jinsu James, Mansoor Noorani, Sattva S. Neelapu, Sairah Ahmed
Publikováno v:
Blood. 138:1740-1740
Introduction. Suboptimal CAR T-cell stimulation, expansion, and persistence is of theoretical concern in absence of CD19+ tumor B-cells. Adequate CAR T-cell expansion has been reported in the JULIET study among 7 relapsed or refractory (r/r) large B-
Autor:
Allison C. Rosenthal, Madiha Iqbal, Amy Ayers, Manali Kamdar, Brian T. Hess, Lei Feng, Arushi Khurana, Sattva S. Neelapu, Yi Lin, Sushanth Gouni, Reid W. Merryman, Paolo Strati, Andrew Ip, Jennifer L. Crombie, Grace Watson
Publikováno v:
Blood. 138:2495-2495
Introduction. About 60% of patients with large B-cell lymphoma (LBCL) relapse after standard of care (SOC) anti-CD19 autologous chimeric antigen receptor (CAR) T-cell therapy, CD19 downregulation representing a major mechanism of resistance. Therefor
Autor:
Sattva S. Neelapu, Ranjit Nair, Daniel Bilbao, Luis Fayad, Paolo Strati, Raphael E Steiner, Jason R. Westin, Francisco Vega, Loretta J. Nastoupil, Sushanth Gouni, Ralf Landgraf, Nitin Agarwal
Publikováno v:
Blood. 136:45-45
Background: Pre-clinical studies show that statins may improve the efficacy of chemoimmunotherapy in patients with DLBCL, through interference with cell membrane-initiated signaling pathways. Clinical retrospective studies, however, yield conflicting
Autor:
Angelique Biancotto, Alexei A. Grom, Yin Liu, Adriana Almeida de Jesus, Alejandro V. Villarino, Bernadette Marrero, Raphaela Goldbach-Mansky, Joseph A. Duncan, Zuoming Deng, Ronald M. Laxer, Yan Huang, Susanne M. Benseler, Sushanth Gouni, Kristien J. M. Zaal, Scott W. Canna, Michael A. DiMattia, Dawn Chapelle, John J. O'Shea, Thomas A. Fleisher, Stephen R. Brooks, Nicole Plass, Hanna Kim, Gina A. Montealegre Sanchez
Publikováno v:
Nature genetics
Inflammasomes are innate immune sensors that respond to pathogen- and damage-associated signals with caspase-1 activation, interleukin (IL)-1β and IL-18 secretion, and macrophage pyroptosis. The discovery that dominant gain-of-function mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64dcae29e96be7611ce685e9650d8f0
Autor:
Susanne M. Benseler, Sushanth Gouni, Bernadette Marrero, G Montealegre, Yan Huang, Stephen R. Brooks, Dawn Chapelle, Nicole Plass, Yin Liu, Ronald M. Laxer, Scott W. Canna, Michael A. DiMattia, Raphaela Goldbach-Mansky, Adriana Almeida de Jesus, Zuoming Deng
Publikováno v:
Arthritis & Rheumatology. 66:S203-S203
Background/Purpose: Macrophage Activation Syndrome (MAS) is a life-threatening systemic inflammatory disorder of unknown etiology. While MAS has no known genetic basis, clinical similarity with a genetic disorder of impaired cytotoxicity known as pri