Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Michel Laviolette"'
Autor:
Anne-Sophie Archambault, Caroline Turcotte, Vincenzo Di Marzo, Marie-Renée Blanchet, Cyril Martin, Michel Laviolette, Élizabeth Dumais, Elyse Y. Bissonnette, Louis-Philippe Boulet, Nicolas Flamand
Publikováno v:
Journal of Leukocyte Biology. 106:1337-1347
2-Arachidonoyl-glycerol (2-AG) is an endocannabinoid with anti-inflammatory properties. Blocking 2-AG hydrolysis to enhance CB2 signaling has proven effective in mouse models of inflammation. However, the expression of 2-AG lipases has never been tho
Publikováno v:
The Journal of allergy and clinical immunology. 148(5)
Autor:
Amine Cheikh, Étienne Doré, Cyril Martin, Anne-Sophie Archambault, Y. Tijani, Hakima Fares, Eric Boilard, Michel Laviolette, Isabelle Dubuc, Youssef Amar, Louis Flamand, Olivier Flamand, Amine El Hassani, Volatiana Rakotoarivelo, Nicolas Flamand, Andréanne Côté, Younes Zaid, Caroline Turcotte
Publikováno v:
The FASEB Journal
Severe acute respiratory syndrome coronavirus 2 is responsible for coronavirus disease 2019 (COVID‐19). While COVID‐19 is often benign, a subset of patients develops severe multilobar pneumonia that can progress to an acute respiratory distress s
Autor:
Michel Laviolette, Marie-Chantal Larose, Anne-Sophie Archambault, Cyril Martin, Caroline Turcotte, Samuel J. Poirier, Julie-S Lefebvre, Véronique Provost, Philippe-Pierre Robichaud, Nicolas Flamand, Patrick P. McDonald, Luc H. Boudreau, Marc E. Surette
Publikováno v:
Journal of Leukocyte Biology. 105:1131-1142
Leukotriene B4 (LTB4) plays a prominent role in innate immunity as it induces phagocyte recruitment, the release of antimicrobial effectors, and as it potentiates the ingestion and killing of pathogens. In humans, LTB4 has a short half-life and is ra
Autor:
Valérie Gagné-Ouellet, Sophie Plante, Marie-Chantal Larose, Anne-Marie Boucher-Lafleur, Nicolas Flamand, Jamila Chakir, Michel Laviolette, Anne-Marie Madore, Catherine Laprise, Miriam Larouche
Publikováno v:
Epigenomics. 10:1555-1568
Aim: This study aimed to characterize DNA methylation (DNA-me) in promoter region of IL33, IL1RL1 and CCL26 in asthma and their impacts on transcriptional activity in bronchial epithelial cells (BECs). Patients & methods: We performed bis-pyrosequenc
Autor:
Michel Laviolette, Philippe Joubert, Julie Turmel, Louis-Philippe Boulet, Michèle Orain, Valérie Bougault, Patricia Odashiro
Publikováno v:
Clinical and Experimental Allergy
Clinical and Experimental Allergy, Wiley, 2018, 48 (12), pp.1748-1751. ⟨10.1111/cea.13257⟩
Clinical and Experimental Allergy, Wiley, 2018, 48 (12), pp.1748-1751. ⟨10.1111/cea.13257⟩
International audience
Autor:
Michel Laviolette, Isabelle Dubuc, Younes Zaid, Nicolas Flamand, Louis Flamand, Olivier Flamand, Anne Sophie Archambault, Étienne Doré, Eric Boilard
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection can lead to a variety of clinical outcomes ranging from the absence of symptoms to severe acute respiratory disease and ultimately death. A feature of patients with sev
Autor:
J. Mark FitzGerald, Richard Leigh, Joel N. Kline, Stephen Lam, Matthew J. Loza, Andreas Eich, Frédéric Baribaud, Patrick Berger, P. Chanez, Philip E. Silkoff, Dave Singh, Vedrana S. Susulic, Steven G. Kelsen, Elliot S. Barnathan, Michel Laviolette, Azra Hussaini, Irina Strambu, William J. Calhoun, Andrea Ludwig-Sengpiel, Geoffrey Chupp, Mark T. Dransfield, Vibeke Backer, Pierre Olivier Girodet, Celeste Porsbjerg
Publikováno v:
Journal of Allergy and Clinical Immunology. 140:710-719
Background The Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study profiled patients with mild, moderate, and severe asthma and nonatopic healthy control subjects. Objective We explored this data set to define type 2 inflammation b
Autor:
Caroline Turcotte, Robert C. Murphy, Cyril Martin, Marie-Renée Blanchet, Michel Laviolette, Nicolas Flamand, David Marsolais, Stéphanie Jean, Simona Zarini
Publikováno v:
The Journal of Immunology. 198:3255-3263
The endocannabinoids 2-arachidonoyl-glycerol and N-arachidonoyl-ethanolamine mediate an array of pro- and anti-inflammatory effects. These effects are related, in part, to their metabolism by eicosanoid biosynthetic enzymes. For example, N-arachidono
Autor:
Michel Laviolette, Suzanne Maahs, Veronica A. Swystun, Louis-Philippe Boulet, Irvin Mayers, Christopher Carlsten, Philip J. Lowe, Barbro Dahlén, Andrej Skerjanec, Miranda Bowen, Richard Leigh, Linda Hui, Beth E. Davis, Richard M. Watson, Gail M. Gauvreau, Kieran J. Killian, Joanne Milot, Anton Drollmann, Paul M. O'Byrne, J. Mark FitzGerald, Ann-Sofie Lantz, Karin Meiser, Nikolaos Lazarinis, Jonathan P. Arm, Donald W. Cockcroft
Publikováno v:
Journal of Allergy and Clinical Immunology. 138:1051-1059
Background Omalizumab is an established anti-IgE therapy for the treatment of allergic diseases that prevents IgE from binding to its receptor. QGE031 is an investigational anti-IgE antibody that binds IgE with higher affinity than omalizumab. Object