Zobrazeno 1 - 10
of 320
pro vyhledávání: '"Jordan S. Orange"'
Autor:
Emily M. Mace, Carl E. Allen, R. Helen Rouce, Asbjørg Stray-Pedersen, Jordan S. Orange, Shalini N. Jhangiani, Olive S. Eckstein, Kenneth L. McClain, M. Cecilia Poli, Ivan K. Chinn, Hey Chong, Nmazuo W. Ozuah, Jason W. Caldwell, Lisa R. Forbes, Erin C. Peckham-Gregory, Tiphanie P. Vogel, Nader Kim El-Mallawany, Juan C. Aldave-Becerra, Joseph Lubega, Jennifer E. Agrusa, Helen E. Heslop, Zeynep H. Coban-Akdemir, James R. Lupski, Francesco Saettini, Nicholas L. Rider, Stephen Jolles, Natalia S. Chaimowitz, Donna M. Muzny, Richard A. Gibbs, Kala Y. Kamdar, Nitya Gulati
Publikováno v:
J Allergy Clin Immunol
Background Pediatric nonmalignant lymphoproliferative disorders (PLPDs) are clinically and genetically heterogeneous. Long-standing immune dysregulation and lymphoproliferation in children may be life-threatening, and a paucity of data exists to guid
Autor:
Jordan S. Orange, Riccardo Castagnoli, Elke Krüger, Marita Bosticardo, Robert A. Krance, Marietta M. de Guzman, Luigi D. Notarangelo, Lisa R. Forbes, M. Cecilia Poli, Ottavia M. Delmonte, Caridad Martinez, Frédéric Ebstein, Sarah K. Nicholas
Publikováno v:
Blood
Inborn errors of immunity that present with concomitant immunodeficiency and auto-inflammation are therapeutically challenging; furthermore, complexity is added when they are caused by mutations in genes that encode for proteins expressed beyond immu
Autor:
Nicholas L. Rider, Michael Coffey, Ashok Kurian, Jessica Quinn, Jordan S. Orange, Vicki Modell, Fred Modell
Publikováno v:
The Journal of allergy and clinical immunology. 151(1)
Identification of patients with underlying inborn errors of immunity and inherent susceptibility to infection remains challenging. The ensuing protracted diagnostic odyssey for such patients often results in greater morbidity and suboptimal outcomes,
Autor:
Jessica Quinn, Vicki Modell, Britt Johnson, Sarah Poll, Swaroop Aradhya, Jordan S. Orange, Fred Modell
Publikováno v:
Frontiers in immunology. 13
Genetic disorders that impair the immune system, known as Primary Immunodeficiencies (PI), include over 450 single-gene inborn errors of immunity. Timely and appropriate diagnosis and treatment is vital to quality of life (QOL) and sometimes survival
Autor:
Kathleen E. Sullivan, Rebecca A. Marsh, Deepti R. Deshpande, Yesim Yilmaz Demirdag, Jordan S. Orange
Publikováno v:
Journal of Clinical Immunology. 41:29-37
DiGeorge syndrome has substantial heterogeneity with variable immune deficiency and dysregulation. Implicated immunopathology includes reduced thymic output and increased peripheral homeostatic proliferation with Th2 skewing and expansion of self-rea
Autor:
Ivan K. Chinn, Jordan S. Orange
Publikováno v:
Expert Review of Clinical Immunology. 16:897-909
Genetic testing of patients with clinically diagnosed or suspected primary immunodeficiencies (PIDs) constitutes standard of care. Choice of testing modality and patient attributes can impact the likelihood of securing a diagnosis.Published diagnosti
Autor:
Marzieh Tavakol, Waleed Al-Herz, Gholamreza Azizi, Arash Kalantari, Asghar Aghamohammadi, Vicki Modell, Ahmed Aziz Bousfiha, Fred Modell, Monireh Mohsenzadegan, Lennart Hammarström, Hossein Esmaeilzadeh, Hassan Abolhassani, Tooba Momen, Mahnaz Sadeghi-Shabestari, Samaneh Delavari, Laleh Sharifi, Reza Yazdani, Antonio Condino-Neto, Mahsa Sohani, Jessica Quinn, Soheila Aleyasin, Mikko Seppänen, Jordan S. Orange, Zahra Chavoshzadeh, Paniz Shirmast, Roya Sherkat, Kathleen E. Sullivan, Hamid Ahanchian, Farahzad Jabbari-Azad, Seyed Alireza Mahdaviani
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
During the last 4 decades, registration of patients with primary immunodeficiencies (PID) has played an essential role in different aspects of these diseases worldwide including epidemiological indexes, policymaking, quality controls of care/life, fa
Autor:
Jessica Quinn, Jennifer Holle, Britt Johnson, Rebecca Truty, Fred Modell, Jordan S. Orange, Swaroop Aradhya, Vicki Modell
Publikováno v:
Immunologic Research
Primary immunodeficiencies (PI) are genetic defects of the immune system that result in chronic and often life-threatening infections and/or life-threatening autoimmunity if not diagnosed and treated. Patients with a suspected PI, but without a genet
Autor:
Ivan K. Chinn, Attila Kumánovics, Monica G. Lawrence, Joud Hajjar, Janet Chou, Jennifer W. Leiding, Jolan E. Walter, Patricia L. Lugar, Maria A. Slack, Morna J. Dorsey, Teresa K. Tarrant, Kathleen E. Sullivan, Jennifer M. Puck, Lisa Kobrynski, Artemio M. Jongco, Neil Romberg, Alice Y. Chan, Kiran Patel, Craig D. Platt, Karin Chen, Jordan S. Orange, Troy R. Torgerson, Michael D. Keller, Nikita Raje
Publikováno v:
Journal of Allergy and Clinical Immunology. 145:46-69
Genetic testing has become an integral component of the diagnostic evaluation of patients with suspected primary immunodeficiency diseases. Results of genetic testing can have a profound effect on clinical management decisions. Therefore clinical pro
Autor:
Musa Karakukcu, Ratnadeep Mukherjee, Lynne A. Wolfe, Aaron Morawski, Lixin Zheng, Niraj C. Patel, Samuel D. Chauvin, Helen F. Matthews, Brian Sellers, Julio C. Orrego-Arango, Tingyan He, Susan Price, Alexandre G. R. Day, Pankaj Mehta, Les R. Folio, Giulia Notarangelo, Jordan S. Orange, James T. Anibal, Evan M. Masutani, Pam Angelus, Chrysi Kanellopoulou, Claudia M. Trujillo-Vargas, Sally Hunsberger, David E. Kleiner, Suk See De Ravin, Jenna R.E. Bergerson, Michael J. Lenardo, Devika Kapuria, Matthew Biancalana, Gulbu Uzel, Mami Matsuda-Lennikov, Sebastian Gutierrez-Hincapie, Alex George, Camilo Toro, Jeffrey I. Cohen, Juan Zou, Ivan K. Chinn, Juan C. Ravell, Ping Jiang, Harry L. Malech, William A. Gahl, Ekrem Unal, Grégoire Altan-Bonnet, Matthias Mann, Kyle Binder, Turkan Patiroglu, Stefania Pittaluga, Astin Powers, Helen C. Su, Kimiyo Raymond, Marc G. Ghany, Sally J. Deeb, José Luis Franco, V. Koneti Rao
Publikováno v:
The Journal of clinical investigation, vol 130, iss 1
J Clin Invest
J Clin Invest
X-linked immunodeficiency with magnesium defect, EBV infection, and neoplasia (XMEN) disease are caused by deficiency of the magnesium transporter 1 (MAGT1) gene. We studied 23 patients with XMEN, 8 of whom were EBV naive. We observed lymphadenopathy