Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jianing Wang"'
Autor:
Xianlin Han, Sijia He, Cheng Zou, Nancy S. Gonzalez, Anindita Bhattacharjee, Shulan Qiu, Jeffrey L. Dupree, Veronica Galvan, Elizabeth Dustin, Juan Pablo Palavicini, Candice E. Van Skike, Lin Ding, Jianing Wang
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-24 (2021)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background Human genetic association studies point to immune response and lipid metabolism, in addition to amyloid-beta (Aβ) and tau, as major pathways in Alzheimer’s disease (AD) etiology. Accumulating evidence suggests that chronic neuroinflamma
Autor:
Dehao Yang, Jiamin Shen, Honghao Huang, Jianing Wang, Fangyue Sun, Tian Zeng, Haojie Qiu, Haobo Xie, Yilin Chen, Shengqi Li, Yiqun Chen, Guangyong Chen, Yiyun Weng
Publikováno v:
Journal of inflammation research. 15
Dehao Yang,1,* Jiamin Shen,2,3,* Honghao Huang,2,3,* Jianing Wang,2,3 Fangyue Sun,2,3 Tian Zeng,2,3 Haojie Qiu,2,4 Haobo Xie,2,3 Yilin Chen,2,3 Shengqi Li,2,3 Yiqun Chen,2,3 Guangyong Chen,2 Yiyun Weng5 1Department of Neurology, The Secon
Publikováno v:
Journal of Autoimmunity. 132:102892
Patients with systemic lupus erythematosus (SLE) frequently suffer from nervous system complications, termed neuropsychiatric lupus erythematosus (NPLE). NPLE accounts for the poor prognosis of SLE. Correct attribution of NP events to SLE is the prim
Autor:
Dehao Yang, Honghao Huang, Yiyun Weng, Junli Ren, Chenguang Yang, Jianing Wang, Beibei Gao, Tian Zeng, Jingyu Hu, Wenjing Pan, Fangyue Sun, Xinbo Zhou, Guangyong Chen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Background and PurposeBlood eosinophil counts are thought to be associated with atherosclerosis in acute ischemic stroke (AIS) and AIS severity. We aimed to investigate 1): the temporal profile of eosinophil in AIS patients treated with recombinant t
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
BackgroundRecently trained immunity of microglia provided an opportunity to study the chronic effect of microglial activation and its metabolic rewiring in neuroimmunological diseases. Since elevated levels of B cell-activating factor (BAFF) have bee
Publikováno v:
Clinical and Experimental Medicine. 19:55-64
Follicular helper T(Tfh) cells and follicular regulatory T(Tfr) cells are critical for the development and maintenance of germinal center and humoral immune responses. Accumulating evidence has demonstrated that the dysregulation of either Tfh or Tfr
Autor:
Na Li, Yongyu Shi, Jianing Wang, Jiahuan Zou, Zhida Wang, Xiaopeng Yu, Lining Zhang, Huaiyu Zhou, Xiaoyan Wang, Rudi Mao, Mengwei Zhuang
Publikováno v:
Molecular Immunology. 101:203-209
The effectiveness of immunotherapy targeting the immune checkpoint PD-L1/PD-1 pathway highlights importance of elucidating the regulatory mechanisms of PD-L1 expression in cancer cells. Previous studies demonstrate that oncogene MYC up-regulates PD-L
Publikováno v:
Cytokine. 99:316-321
Objective To examine the expression of chemokine receptors in different peripheral blood T-cell subsets in patients with polymyositis (PM) and dermatomyositis (DM). Methods We used flow cytometry to measure the frequencies of chemokine receptors CXCR
Publikováno v:
Journal of Neuroimmunology. 310:135-142
To investigate the potential involvement of microglia in the neuropathology of systemic lupus erythematosus (SLE), we examined whether SLE patient sera could activate BV2 microglia in vitro. Exposure to SLE patient sera resulted in morphological chan
Autor:
Kyong Nyon Nam, Anais Mounier, Hafsa I. Kamboh, Nicholas F. Fitz, Iliya Lefterov, Xianlin Han, Cody M. Wolfe, Radosveta Koldamova, Valerie L. Reeves, Jonathan Schug, Emilie L. Castranio, Alexis Y. Carter, Jianing Wang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
We examined the effect of chronic high fat diet (HFD) on amyloid deposition and cognition of 12-months old APP23 mice, and correlated the phenotype to brain transcriptome and lipidome. HFD significantly increased amyloid plaques and worsened cognitiv