Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jan Meeldijk"'
Increased intra-articular granzyme M may trigger local IFN-λ1/IL-29 response in rheumatoid arthritis
Autor:
Liling Shan, Lucas L. van den Hoogen, Jan Meeldijk, Helena M. Kok, Lieneke H. Jongeneel, Marianne Boes, Mark H. Wenink, C. Erik Hack, Timothy R.D.J. Radstake, Joel A.G. van Roon, Niels Bovenschen
Publikováno v:
Clinical and Experimental Rheumatology. 38:220-226
Autor:
Saskia V. Vijver, Akashdip Singh, Eline T. A. M. Mommers-Elshof, Jan Meeldijk, Ronald Copeland, Louis Boon, Sol Langermann, Dallas Flies, Linde Meyaard, M. Inês Pascoal Ramos
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
The tumor microenvironment (TME) is a complex structure comprised of tumor, immune and stromal cells, vasculature, and extracellular matrix (ECM). During tumor development, ECM homeostasis is dysregulated. Collagen remodeling by matrix metalloprotein
Autor:
Martin Potts, Bernadet Blijenberg, Thomas Stamminger, Adriana Svrlanska, Niels Bovenschen, Astrid Hendriks, Ian J. Groves, Liling Shan, Sara P. H. van den Berg, Jan Meeldijk, Karlijn J. W. M. van Boxtel, Shuang Li, Mark R. Wills
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 4, p e1008426 (2020)
PLoS Pathogens, Vol 16, Iss 4, p e1008426 (2020)
Human cytomegalovirus (HCMV) is the most frequent viral cause of congenital defects and can trigger devastating disease in immune-suppressed patients. Cytotoxic lymphocytes (CD8+ T cells and NK cells) control HCMV infection by releasing interferon-γ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d435840b4eae7def284bb4353e27925
Autor:
Rolf T. Urbanus, Kim Dijkxhoorn, Karen Silence, Peter Boross, Elisabeth de Zeeuw, Louis Boon, Jan Meeldijk, Christophe Blanchetot, Jeanette H. W. Leusen, Sofie Gabriels, Henny G. Otten, Liesbeth Van de Ven, Kevin Budding, Hans de Haard, Jean-Michel Percier, Rob Holgate, Peter J. Simons, Johanna Wildemann, C. Erik Hack, Inge Van de Walle, Linda J. Cox, Cafer Yildiz
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background Activation of the classical and lectin pathway of complement may contribute to tissue damage and organ dysfunction of antibody-mediated diseases and ischemia-reperfusion conditions. Complement factors are being considered as targets for th
Autor:
Daan Augustijn, Karli R. Reiding, C. Erik Hack, Louis J. Bont, Maaike Nederend, Jeanette H. W. Leusen, Manfred Wuhrer, Frank E. J. Coenjaerts, Shamir R. Jacobino, Jan Meeldijk, J. H. Marco Jansen, J. Frederiek Reijneveld
Publikováno v:
mAbs, 10(3), 453. Landes Bioscience
mAbs
mAbs, 10(3), 453-462
mAbs
mAbs, 10(3), 453-462
Respiratory syncytial virus (RSV) infection is a leading cause of hospitalization and mortality in young children. Protective therapy options are limited. Currently, palivizumab, a monoclonal IgG1 antibody, is the only licensed drug for RSV prophylax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3cd91f31232627ce6680f38ab00673
https://doi.org/10.1080/19420862.2018.1433974
https://doi.org/10.1080/19420862.2018.1433974
Autor:
Marianne Boes, Robert van der Burgh, Joost Frenkel, Lieneke Jongeneel, Marielle E. van Gijn, Niels Bovenschen, Jan Meeldijk
Publikováno v:
Oncotarget, 7(15), 19265. Impact Journals
Oncotarget
Oncotarget
Patients who suffer from autoinflammatory disease (AID) exhibit seemingly uncontrolled release of interleukin (IL)-1β. The presence of this inflammatory cytokine triggers immune activation in absence of pathogens and foreign material. The mechanisms
Autor:
Elena G. Kamburova, Tineke Kardol-Hoefnagel, Bram W. Wisse, Irma Joosten, Wil A. Allebes, Arnold van der Meer, Luuk B. Hilbrands, Marije C. Baas, Eric Spierings, Cornelis E. Hack, Franka E. van Reekum, Arjan D. van Zuilen, Marianne C. Verhaar, Michiel L. Bots, Adriaan C. A. D. Drop, Loes Plaisier, Jan Meeldijk, Niels Bovenschen, Marc A. J. Seelen, Jan Stephan Sanders, Bouke G. Hepkema, Annechien J. A. Lambeck, Laura B. Bungener, Caroline Roozendaal, Marcel G. J. Tilanus, Christina E. Voorter, Lotte Wieten, Elly M. van Duijnhoven, Mariëlle A. C. J. Gelens, Maarten H. L. Christiaans, Frans J. van Ittersum, Shaikh A. Nurmohamed, Neubury M. Lardy, Wendy Swelsen, Karlijn A. M. I. van der Pant, Neelke C. van der Weerd, Ineke J. M. ten Berge, Frederike J. Bemelman, Paul J. M. van der Boog, Johan W. de Fijter, Michiel G. H. Betjes, Sebastiaan Heidt, Dave L. Roelen, Frans H. Claas, Henny G. Otten
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, 9:3002. Frontiers Media S.A.
Frontiers in Immunology, 9. Frontiers Media S.A.
Frontiers in Immunology, 9:3002, 1-12. Frontiers Media S.A.
Kamburova, E G, Kardol-Hoefnagel, T, Wisse, B W, Joosten, I, Allebes, W A, van der Meer, A, Hilbrands, L B, Baas, M C, Spierings, E, Hack, C E, van Reekum, F E, van Zuilen, A D, Verhaar, M C, Bots, M L, Drop, A C A D, Plaisier, L, Meeldijk, J, Bovenschen, N, Seelen, M A J, Sanders, J S, Hepkema, B G, Lambeck, A J A, Bungener, L B, Roozendaal, C, Tilanus, M G J, Voorter, C E, Wieten, L, van Duijnhoven, E M, Gelens, M A C J, Christiaans, M H L, van Ittersum, F J, Nurmohamed, S A, Lardy, N M, Swelsen, W, van der Pant, K A M I, van der Weerd, N C, Ten Berge, I J M, Bemelman, F J, van der Boog, P J M, de Fijter, J W, Betjes, M G H, Heidt, S, Roelen, D L, Claas, F H & Otten, H G 2018, ' Development and Validation of a Multiplex Non-HLA Antibody Assay for the Screening of Kidney Transplant Recipients ', Frontiers in Immunology, vol. 9 . https://doi.org/10.3389/fimmu.2018.03002
Frontiers in immunology, 9. Frontiers Media S.A.
Frontiers in Immunology, 9:3002. Frontiers Media SA
Frontiers in Immunology, 9
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, 9. Frontiers Media S. A.
Frontiers in Immunology, 9:3002. Frontiers Media S.A.
Frontiers in Immunology, 9. Frontiers Media S.A.
Frontiers in Immunology, 9:3002, 1-12. Frontiers Media S.A.
Kamburova, E G, Kardol-Hoefnagel, T, Wisse, B W, Joosten, I, Allebes, W A, van der Meer, A, Hilbrands, L B, Baas, M C, Spierings, E, Hack, C E, van Reekum, F E, van Zuilen, A D, Verhaar, M C, Bots, M L, Drop, A C A D, Plaisier, L, Meeldijk, J, Bovenschen, N, Seelen, M A J, Sanders, J S, Hepkema, B G, Lambeck, A J A, Bungener, L B, Roozendaal, C, Tilanus, M G J, Voorter, C E, Wieten, L, van Duijnhoven, E M, Gelens, M A C J, Christiaans, M H L, van Ittersum, F J, Nurmohamed, S A, Lardy, N M, Swelsen, W, van der Pant, K A M I, van der Weerd, N C, Ten Berge, I J M, Bemelman, F J, van der Boog, P J M, de Fijter, J W, Betjes, M G H, Heidt, S, Roelen, D L, Claas, F H & Otten, H G 2018, ' Development and Validation of a Multiplex Non-HLA Antibody Assay for the Screening of Kidney Transplant Recipients ', Frontiers in Immunology, vol. 9 . https://doi.org/10.3389/fimmu.2018.03002
Frontiers in immunology, 9. Frontiers Media S.A.
Frontiers in Immunology, 9:3002. Frontiers Media SA
Frontiers in Immunology, 9
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, 9. Frontiers Media S. A.
The best treatment for patients with end-stage renal disease is kidney transplantation. Although graft survival rates have improved in the last decades, patients still may lose their grafts partly due to the detrimental effects of donor-specific anti
Autor:
Roel Broekhuizen, Stefanie A. H. de Poot, Jan Meeldijk, Elisabeth M. P. Steeghs, Elisabeth A. van Erp, Roel Goldschmeding, Niels Bovenschen, Marjolein C. Olthof
Publikováno v:
Blood. 126:2893-2895
To the editor: With great interest, we read the recent Blood article by Vrazo et al,[1][1] who report on the use of luciferase-based biosensors to detect proteolytic activity of granzymes (Gr’s) A, B, and K. They show that these sensors can be used
Autor:
Karli R. Reiding, Saskia Meyer, Jan Meeldijk, Peter Boross, Jeanette H. W. Leusen, Manfred Wuhrer, Maaike Nederend, Shamir R. Jacobino, Ruud Ubink, J. H. Marco Jansen, Niels Bovenschen, Thomas Valerius, Gerard J. A. Rouwendal
Publikováno v:
mAbs
mAbs, 8(1), 87. Landes Bioscience
mAbs, 8(1), 87-98
mAbs, 8(1), 87. Landes Bioscience
mAbs, 8(1), 87-98
Antibody therapy is a validated treatment approach for several malignancies. All currently clinically applied therapeutic antibodies (Abs) are of the IgG isotype. However, not all patients respond to this therapy and relapses can occur. IgA represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb40508c828137c17bb9ccbdd2c1a9c
https://doi.org/10.1080/19420862.2015.1106658
https://doi.org/10.1080/19420862.2015.1106658
Publikováno v:
Cell Death & Disease
Granzymes are a family of homologous serine proteases involved in inducing apoptosis in virus-infected cells and tumor cells.1, 2 In humans, five granzymes (GrA, GrB, GrH, GrK, and GrM) are expressed, and stored in granules of natural killer (NK) cel