Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Han Moshage"'
Publikováno v:
Virus research. 263:1-8
Oxidative- and endoplasmic reticulum (ER)-stress are common events during hepatitis C virus (HCV) infection and both regulate cell survival and determine clinical outcome. In response to intrinsic and extrinsic cellular stress, different adaptive mec
Autor:
Glenn Marsman, Marten H. Hofker, Iris Jonkers, Vinod Kumar, Jingyuan Fu, Han Moshage, Cisca Wijmenga, Marijke R. van der Sijde, Bart van de Sluis, Sebo Withoff, Sander S. Rensen, Klaas Nico Faber, Jan Greve, Ronit Shiri-Sverdlov, Biljana Atanasovska
Publikováno v:
Hepatology, 66(3), 794-808. Wiley
Hepatocyte apoptosis in nonalcoholic steatohepatitis (NASH) can lead to fibrosis and cirrhosis, which permanently damage the liver. Understanding the regulation of hepatocyte apoptosis is therefore important to identify therapeutic targets that may p
Autor:
Xiajiong Luo, Bozhi Cai, Klaas Nico Faber, Dai-Fei Shen, Peixuan Yang, Jiyang Jiang, Lijun Li, He Cheng, Xueting Bai, Qiaoling Zhou, Han Moshage, Ganggang Shi, Manon Buist-Homan
Publikováno v:
British Journal of Pharmacology. 174:41-56
Background and Purpose Liver diseases are mostly accompanied by inflammation and hepatocyte death. Therapeutic approaches targeting both hepatocyte injury and inflammation are not available. Natural compounds are considered as potential treatment for
Autor:
Margarita Pizarro, Juan Pablo Arab, Han Moshage, Enrique Brandan, Daniel Cabrera, Francisco Barrera, Marco Arrese, Claudio Cabello-Verrugio, Davide Povero, Nancy Solís, Javiera Torres, Ariel E. Feldstein, Alejandra Hernandez, Alexander Wree
Publikováno v:
Scientific reports 7, 3491 (2017). doi:10.1038/s41598-017-03675-z
Scientific Reports
Scientific Reports, 7(1):3491. Nature Publishing Group
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports, 7(1):3491. Nature Publishing Group
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Indexación: Scopus. Therapy for nonalcoholic steatohepatitis (NASH) is limited. Andrographolide (ANDRO), a botanical compound, has a potent anti-inflammatory activity due to its ability to inhibit NF-κB. ANDRO has been also shown to inhibit the NLR
Autor:
Saravanan Yuvaraj, Maikel P. Peppelenbosch, Nicolaas A. Bos, Judy C. A. M. Bun, Han-Qing Jiang, Han Moshage, Gerard Dijkstra, John J. Cebra, Natasha Kushnir
Publikováno v:
Inflammatory Bowel Diseases, 13(12), 1467-1474. LIPPINCOTT WILLIAMS & WILKINS
Background: Both the role of inducible nitric oxide synthase (iNOS) in the development of inflammatory bowel disease (IBD) as well as the molecular details governing its mucosal induction remain unclear. Methods: In the present study we evaluated the
Autor:
Harry van Goor, Klaas Nico Faber, Peter L.M. Jansen, Han Moshage, Gerard Dijkstra, Hans Blokzijl, M Homan, Lisette Bok
Publikováno v:
Journal of pathology, 204(3), 296-303. John Wiley and Sons Ltd
JOURNAL OF PATHOLOGY, 204(3), 296-303. Wiley
JOURNAL OF PATHOLOGY, 204(3), 296-303. Wiley
Inducible nitric oxide synthase (iNOS) is expressed in intestinal epithelial cells (IEC) of patients with active inflammatory bowel disease (IBD) and in IEC of endotoxaemic rats. The induction of MOS in IEC is an element of the NF-KB-mediated surviva
Autor:
Marieke H. Schoemaker, Han Moshage
Publikováno v:
Clinical Science. 107:13-25
Acute liver injury can develop as a consequence of viral hepatitis, drug- or toxin-induced toxicity or rejection after liver transplantation, whereas chronic liver injury can be due to long-term exposure to alcohol, chemicals, chronic viral hepatitis
Publikováno v:
Scandinavian journal of gastroenterology, 37(Suppl. 236), 37-41. Informa Healthcare
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37, 37-41. Taylor & Francis Group
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 37, 37-41. Taylor & Francis Group
Background: Inhibition of NF-kappaB activation has been suggested as an anti-inflammatory treatment strategy in inflammatory bowel disease (IBD). However, NF-kappaB regulated genes like inducible nitric oxide synthase (iNOS) are also involved in cell
Autor:
Marian L.C. van der Horst, Harry van Goor, Alie de Jager-Krikken, Pieter A. Klok, Winston W. Bakker, Ester W.J.A. Albrecht, Peter Heeringa, Han Moshage
Publikováno v:
Nitric oxide-Biology and chemistry, 5(6), 525-533. ACADEMIC PRESS INC ELSEVIER SCIENCE
In the present paper we studied the role of nitric oxide radicals (NO) on platelet aggregation, fibrinogen deposition, superoxide formation, peroxynitrite formation, hemodynamics, and leukocyte migration in the Thy-1 model of glomerulonephritis. To f
Autor:
Han Moshage
Publikováno v:
University of Groningen
The acute phase response is an orchestrated response to tissue injury, infection or inflammation. A prominent feature of this response is the induction of acute phase proteins, which are involved in the restoration of homeostasis. Cytokines are impor