Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Doron Merkler"'
Autor:
Danielle Shlesinger, Kai-Lin Hong, Ghazal Shammas, Nicolas Page, Ioana Sandu, Andreas Agrafiotis, Victor Kreiner, Nicolas Fonta, Ilena Vincenti, Ingrid Wagner, Margot Piccinno, Alexandre Mariotte, Bogna Klimek, Raphael Dizerens, Marcos Manero-Carranza, Raphael Kuhn, Roy Ehling, Lester Frei, Keywan Khodaverdi, Camilla Panetti, Nicole Joller, Annette Oxenius, Doron Merkler, Sai T. Reddy, Alexander Yermanos
Publikováno v:
Genes and Immunity, 23
Adaptive immune repertoires are composed by the ensemble of B and T-cell receptors within an individual, reflecting both past and current immune responses. Recent advances in single-cell sequencing enable recovery of the complete adaptive immune rece
Autor:
Anna-Friederike Marx, Sandra M. Kallert, Tobias M. Brunner, José A. Villegas, Florian Geier, Jonas Fixemer, Tiago Abreu-Mota, Peter Reuther, Weldy V. Bonilla, Jelizaveta Fadejeva, Mario Kreutzfeldt, Ingrid Wagner, Patricia Aparicio-Domingo, Leo Scarpellino, Mélanie Charmoy, Daniel T. Utzschneider, Claudia Hagedorn, Min Lu, Karen Cornille, Karsten Stauffer, Florian Kreppel, Doron Merkler, Dietmar Zehn, Werner Held, Sanjiv A. Luther, Max Löhning, Daniel D. Pinschewer
Raw data underlying the publication 
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0438be1f4fda60bf438a80bbf2ea221
Autor:
Juliane K. Lohmeyer, Toshihito Hirai, Mustafa Turkoz, Stephane Buhler, Teresa Lopes Ramos, Natalie Köhler, Jeanette Baker, Astrid Melotti, Ingrid Wagner, Amandine Pradier, Sisi Wang, Xuhuai Ji, Simone Becattini, Jean Villard, Doron Merkler, Yves Chalandon, Robert S. Negrin, Federico Simonetta
Publikováno v:
Blood.
CD4+FOXP3+ regulatory T cells (Tregs) have demonstrated efficacy in the prevention and treatment of graft-versus-host disease (GVHD). Preclinical and clinical studies indicate that Tregs are able to protect from GVHD without interfering with the graf
Autor:
Raphael Kuhn, Sai T. Reddy, Danielle Shlesinger, Lucia Csepregi, Alexander Yermanos, Daniel Neumeier, Laura Hauri, Andreas Agrafiotis, Annette Oxenius, Victor Greiff, Alessandro Pedrioli, Damiano Robbiani, Doron Merkler, Roy A. Ehling, Alessandro Genovese, Ioana Sandu, Chrysa Papadopoulou, Kai-Lin Hong, Jiami Han
Publikováno v:
European Journal of Immunology, 52 (2)
Plasma cells and their secreted antibodies play a central role in the long-term protection against chronic viral infection. However, due to experimental limitations, a comprehensive description of linked genotypic, phenotypic, and antibody repertoire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8298233de6de4d07f0694448429f354
https://hdl.handle.net/20.500.11850/518628
https://hdl.handle.net/20.500.11850/518628
Publikováno v:
Current Opinion in Immunology
Current Opinion in Immunology, 2022, 77, pp.102211. ⟨10.1016/j.coi.2022.102211⟩
Current Opinion in Immunology, 2022, 77, pp.102211. ⟨10.1016/j.coi.2022.102211⟩
International audience; Tissue-resident memory T cells (T RM) represent a subset of antigen-experienced T cells that are constantly retained in a given tissue with limited traf cking through the circulation. These cells are characterized by expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8993b4c205a6efe52b4a581ec620f74
https://hal.science/hal-03749081/document
https://hal.science/hal-03749081/document
In Vivo Function of the Lipid Raft Protein Flotillin-1 during CD8+ T Cell–Mediated Host Surveillance
Autor:
Ben J. Nichols, Nora Ruef, Nicolas Page, Guerric P. B. Samson, Verena Niggli, Jens V. Stein, Daniel F. Legler, Xenia Ficht, Federica Moalli, Doron Merkler, Alba Diz-Muñoz, Bettina Stolp
Publikováno v:
Journal of Immunology, Vol. 203, No 9 (2019) pp. 2377-2387
Flotillin-1 (Flot1) is an evolutionary conserved, ubiquitously expressed lipid raft–associated scaffolding protein. Migration of Flot1-deficient neutrophils is impaired because of a decrease in myosin II–mediated contractility. Flot1 also accumul
Autor:
Doron Merkler, Ingrid Wagner, Mario Kreutzfeldt, Karen Cornille, Tobias M. Brunner, Marco Künzli, David Schreiner, Kerstin Narr, Mirela Dimitrova, Yusuf I. Ertuna, Lukas Bestmann, Benedict Fallet, Max Löhning, Carolyn G. King, Tiago Jose Abreu Mota, Anna-Friederike Marx, Florian Geier, Katrin Martin, Daniel D. Pinschewer
Publikováno v:
Proc Natl Acad Sci U S A
Chronic viral infections subvert protective B cell immunity. An early type I interferon (IFN-I)-driven bias to short-lived plasmablast differentiation leads to clonal deletion, so-called "decimation," of antiviral memory B cells. Therefore, prophylac
Autor:
Nicolas A. Gort-Freitas, Christina Pfirschke, Anna Kohl, Doron Merkler, Marie Siwicki, Yoshiko Iwamoto, Chiara Cianciaruso, Rapolas Zilionis, Marius Messemaker, Sara I. Pai, John E. Mindur, Montserrat Fraga, Pierre-Yves Dietrich, Angela E. Zou, Alexander Coukos, Christine Sempoux, Yi-Jang Lin, Nilesh Talele, Cecile Piot, Thibaud Koessler, Alexandre Wicky, Rakesh K. Jain, Yunkang Lin, Mikael J. Pittet, Rainer H. Kohler, Ruben Bill, Christopher Garris, Camilla Engblom, Jeremy Gungabeesoon, Allon M. Klein, Claudio deVito, Olivier Michielin, Ralph Weissleder, Evangelia Bolli, Genevieve M. Gerhard, Mari Mino-Kenudson
Publikováno v:
Sci Immunol
Science Immunology, Vol. 6, No 61 (2021) P. eabi7083
Science Immunology, Vol. 6, No 61 (2021) P. eabi7083
Immunotherapy is revolutionizing cancer treatment but is often restricted by toxicities. What distinguishes adverse events from concomitant antitumor reactions is poorly understood. Here, using anti-CD40-treatment in mice as a model of Th1-promoting
Autor:
Katrin Martin, Daniel D. Pinschewer, Mario Kreutzfeldt, Matias Ciancaglini, Doron Merkler, Florian Geier, Peter Reuther, Diego Calabrese
Publikováno v:
The Journal of experimental medicine. 218(10)
Several RNA viruses can establish life-long persistent infection in mammalian hosts, but the fate of individual virus-infected cells remains undefined. Here we used Cre recombinase–encoding lymphocytic choriomeningitis virus to establish persistent
Autor:
Annette Oxenius, Sai T. Reddy, Mariana Borsa, Doron Merkler, Ann Cathrin Waindok, Ioana Sandu, Alexander Yermanos, Daniel Neumeier
Publikováno v:
Proceedings. Biological sciences, Vol. 288, No 1945 (2021) P. 20202793
Proc Biol Sci
Proc Biol Sci
Neuroinflammation plays a crucial role during ageing and various neurological conditions, including Alzheimer’s disease, multiple sclerosis and infection. Technical limitations, however, have prevented an integrative analysis of how lymphocyte immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32814aa2b7c6444c7e695895e3a3039c
https://archive-ouverte.unige.ch/unige:151697
https://archive-ouverte.unige.ch/unige:151697