Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Daire O'Shea"'
Autor:
Deepali Kumar, Anders Åsberg, Luiz F. Lisboa, Atul Humar, Daire O'Shea, Vincent C. Emery, Adrian Egli, Thomas F. Mueller
Publikováno v:
American Journal of Transplantation
Human (Homo sapiens) micro-RNAs (hsa-miRNAs) regulate virus and host-gene translation, but the biological impact in patients with human cytomegalovirus (hCMV) infection is not well defined in a clinically relevant model. First, we compared hsa-miRNA
Autor:
Sarah C. Forester, John Lok Man Law, Donna N. Douglas, Michael Houghton, Gary Lund, Atul Humar, Mansun Law, Daire O'Shea, Joshua D. Lambert, David L.J. Tyrrell, Norman M. Kneteman, Adrian Egli, Dennis R. Burton
Publikováno v:
Liver Transplantation. 22:324-332
The anti-hepatitis C virus (HCV) activity of a novel monoclonal antibody (mAb; AR4A) and epigallocatechin gallate (EGCG) were studied in vitro using a HCV cell culture system and in vivo using a humanized liver mouse model capable of supporting HCV r
Autor:
Shahid Husain, Atul Humar, Oriol Manuel, Jared Fairbanks, Daire O'Shea, Deepali Kumar, Luiz F. Lisboa, Adrian Egli
Publikováno v:
American Journal of Transplantation. 15:1882-1892
Monitoring of cytomegalovirus cell-mediated immunity is a promising tool for the refinement of preventative and therapeutic strategies posttransplantation. Typically, the interferon-γ response to T cell stimulation is measured. We evaluated a broad
Autor:
Joerg Stelling, Michael Houghton, Thomas F. Mueller, Atul Humar, Luiz F. Lisboa, Lukas A. Widmer, Daire O'Shea, Adrian Egli, Deepali Kumar, Aliyah Baluch, Deanna M. Santer
Publikováno v:
The Journal of Infectious Diseases, 212 (1)
JOURNAL OF INFECTIOUS DISEASES
JOURNAL OF INFECTIOUS DISEASES
Background Influenza vaccine immunogenicity is suboptimal in immunocompromised patients. However, there are limited data on the interplay of T- and B- cell responses to vaccination with simultaneous immunosuppression. Methods We collected peripheral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167fdf71a160cc0ca481b2c268359a8a
http://doc.rero.ch/record/303034/files/jiv015.pdf
http://doc.rero.ch/record/303034/files/jiv015.pdf
Autor:
Manuel Battegay, Aliyah Baluch, Daire O'Shea, Nina Khanna, Deanna M. Santer, Khaled Barakat, Thomas F. Mueller, Deepali Kumar, D. Lorne Tyrrell, Mohammedyaseen Syedbasha, Adrian Egli, Jody Groenendyk, Luiz F. Lisboa, Atul Humar, Michael Houghton, Rakesh Bhat, Madeleine Vollmer, Michael A. Joyce, Brad S. Thomas
Publikováno v:
PLoS Pathogens, Vol 10, Iss 12, p e1004556 (2014)
PLoS Pathogens
PLoS Pathogens
Influenza is a major cause of morbidity and mortality in immunosuppressed persons, and vaccination often confers insufficient protection. IL-28B, a member of the interferon (IFN)-λ family, has variable expression due to single nucleotide polymorphis
Autor:
Xiao-Li Pang, Anders Åsberg, Daire O'Shea, Halvor Rollag, Atul Humar, D. L. Tyrrell, Luiz F. Lisboa, Deepali Kumar, Anders Hartmann, Adrian Egli
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 15(7)
Cytomegalovirus (CMV) encodes multiple microRNAs. While these have been partially characterized in vitro, their relevance to clinical CMV infection has not been evaluated. We analyzed samples from a cohort of solid organ transplant patients with CMV
Publikováno v:
Current infectious disease reports. 16(9)
Infection prevention is a key component of care and an important determinant of clinical outcomes in a diverse population of immunocompromised hosts. Vaccination remains a fundamental preventative strategy, and clear guidelines exist for the vaccinat
Autor:
Daire O'Shea, Khaled Barakat, Adrian Egli, Nina Khanna, Deepali Kumar, Aviad Levin, D. Lorne Tyrrell, Manuel Battegay, Martin S. Zand, Maja Weisser, Madeleine Vollmer, Michael Houghton, Deanna M. Santer
Publikováno v:
Swiss Medical Weekly.
Infectious pathogens are responsible for high utilisation of healthcare resources globally. Attributable morbidity and mortality remains exceptionally high. Vaccines offer the potential to prime a pathogen-specific immune response and subsequently re
Publikováno v:
Emerging Microbes & Infections
Type-III interferons (IFN-λ, IFNL) are the most recently described family of IFNs. This family of innate cytokines are increasingly being ascribed pivotal roles in host-pathogen interactions. Herein, we will review the accumulating evidence detailin
Autor:
Daire O'Shea, G. Farrell, Clair M. Gardiner, Markus Peck-Radosavljevic, Thomas Reiberger, Colm Bergin, C Keane
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66831 (2013)
PLoS ONE
PLoS ONE
Pegylated-IFN and ribavirin remains the current treatment for chronic HCV infection in patients co-infected with HIV-1, but this regimen has low efficacy rates, particularly for HCV genotype 1/4 infection, has severe side effects and is extremely cos