Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Benjamin Kim"'
Publikováno v:
Blood. 140:8336-8337
Autor:
Lilley Leong, Tony Byun, Benjamin Kim, Ian Huck, Abel Silva, Joanne Chan, Young Cho, John Liu, Christopher J. Horvath, Stephen J. Moore, Sandip Panicker
Publikováno v:
Blood. 140:1666-1667
Autor:
Emily Symington, Glenn F. Pierce, Adam Giermasz, K. John Pasi, Stefan Tiefenbacher, Stephen J. Zoog, Mary Robinson, Savita Rangarajan, Steffen Rosen, Christian Vettermann, Donnie Mackenzie, Jaydeep K. Srimani, Benjamin Kim, Mei Huang, Terri Christianson
Publikováno v:
Blood. 136:2524-2534
Adeno-associated virus (AAV)-based gene therapies can restore endogenous factor VIII (FVIII) expression in hemophilia A (HA). AAV vectors typically use a B-domain–deleted FVIII transgene, such as human FVIII-SQ in valoctocogene roxaparvovec (AAV5-F
Autor:
Jane A. Mason, Konstantia-Maria Chavele, Doris Quon, Sheng-Chieh Chou, Gili Kenet, Bella Madan, Margareth C. Ozelo, Susan Shapiro, Radoslaw Kaczmarek, Benjamin Kim, Hua Yu, Amy L. Dunn, Emily Symington, Nigel S. Key, Steven W. Pipe, Michael Laffan, Tara M Robinson, Mark T. Reding, Wing Yen Wong, Reena Mahajan, Adebayo Lawal, Michael Wang, Divya B Reddy, Annette von Drygalski, Andrew D. Leavitt
Publikováno v:
Blood. 138:3972-3972
Introduction. Valoctocogene roxaparvovec (AAV5-hFVIII-SQ) is an adeno-associated virus gene therapy that transfers a B-domain deleted factor VIII (FVIII) cDNA to hepatocytes. The open-label, single-arm, multicenter phase 3 GENEr8-1 trial (NCT03370913
Autor:
Kevin Hammon, Benjamin Kim, Chris B. Russell, Annie Clark, Joshua Henshaw, Jennifer Holcomb, Kala Jayaram, Elli Koziol, Krystal Sandza, Christian Vettermann, Richard Torres
Publikováno v:
Blood. 136:21-21
Introduction: Long-term durable expression of hFVIII-SQ has been observed following BMN 270 (AAV5-hFVIII-SQ, valoctocogene roxaparvovec) single-dose administration in patients with severe hemophilia A. Although adeno-associated virus (AAV) vectors ar
Autor:
Benjamin Kim, Victor J. Marder, Zachary A. Hing, Zuben E. Sauna, Eric J. Broxham, Chava Kimchi-Sarfaty, David Liuwantara, Pamela Kempert, Tal Schiller, Tom E. Howard, Nathan C. Edwards, Vijaya L. Simhadri, Andrew Wu, Evi B. Struble
Publikováno v:
British Journal of Haematology. 165:154-158
Background Although autosomal recessive hematologic disorders are individually rare and difficult to ascertain, studies involving one or more homozygous affected children and their unaffected heterozygous parents have led to expanded understanding of
Autor:
Morvarid Moayeri, Andrew D. Leavitt, Cyril Jacquot, Sarah B. Shugarts, Kara L. Lynch, Benjamin Kim
Publikováno v:
Transfusion. 53:2715-2721
Background Antibody-mediated drug-induced thrombocytopenia (DIT) typically requires the presence of the sensitizing drug in the plasma. Therefore, platelet (PLT) counts often start to recover 1 to 2 days after discontinuation of the offending medicat
Autor:
Prateek Mendiratta, Alfred Rademaker, Martin S. Tallman, Punit Chadha, Benjamin Kim, LoAnn Peterson, David Hakimian, Darren Evanchuk
Publikováno v:
Blood. 106:241-246
2-chlorodeoxyadenosine (2-CdA), a purine analog, has become universally accepted as the agent of choice in treating hairy cell leukemia (HCL). However, few studies have reported long-term outcomes after 2-CdA treatment. Between January 1990 and June
Autor:
Shelley A. Cole, Zuben E. Sauna, Chen Yanover, Kevin R. Viel, Tom E. Howard, Benjamin Kim, Afshin Ameri, Raja Rajalingam
Publikováno v:
Europe PubMed Central
Author(s): Sauna, ZE; Ameri, A; Kim, B; Yanover, C; Viel, KR; Rajalingam, R; Cole, SA; Howard, TE
Publikováno v:
Journal of Surgical Research. 50:480-484
A newly developed monoclonal rat IgG 2b antibody which in vitro can activate both helper and cytolytic T-lymphocytes by binding to the CD3 epsilon subunit of the T-cell receptor complex was tested alone and in combination with Interleukin-2, a growth