Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Anna Mae Diehl"'
Autor:
Michael Wagner, Justin P. Wright, Sharon Jiang, Thomas M. O’Connell, Lawrence A. David, Fátima C. Pereira, Anna Mae Diehl, Richard T. Premont, Tyler R. Kartzinel, David Berry, Anchi Wu, Arno Schintlmeister, Robert M. Pringle, Heather K. Durand, Robert R. Dunn, Xiyou Zhou, Aspen T. Reese, Susan C. Alberts, Laura P. Hale
Publikováno v:
Nature Microbiology
Nature microbiology
Nature microbiology
Resource limitation is a fundamental factor governing the composition and function of ecological communities. However, the role of resource supply in structuring the intestinal microbiome has not been established and represents a challenge for mammal
Autor:
Andrea G. Nackley, Wolfgang Liedtke, Anna Mae Diehl, Huiping Ding, Andreas E. Kremer, Johannes Morstein, Ana E. López-Romero, Qian Zeng, Zilong Wang, Ru-Rong Ji, Qiaojuan Zhang, Yong Chen, Xin Zhang, Piotr Milkiewicz, Tony E. Reeves, Sara L. Morales-Lázaro, Jennifer Y. Zhang, Marcin Krawczyk, Tamara Rosenbaum, Mei-Chuan Ko, Frank Lammert, Andrey V. Bortsov, Manal F. Abdelmalek, Michele Yeo, Huanghe Yang, Carlene Moore, Ying-Ai Jin
Publikováno v:
Gastroenterology. 161(1)
Background & Aims Limited understanding of pruritus mechanisms in cholestatic liver diseases hinders development of antipruritic treatments. Previous studies implicated lysophosphatidic acid (LPA) as a potential mediator of cholestatic pruritus. Meth
Autor:
Franklin G. Berger, Balaraman Kalyanaraman, Anna Mae Diehl, Varun Chandrashekaran, Jacek Ziolenka, Diptadip Dattaroy, Firas Alhasson, James A. Carson, Ratanesh Seth, Saurabh Chatterjee
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 8-19 (2017)
Redox Biology
Redox Biology
Recent clinical studies found a strong association of colonic inflammation and Inflammatory bowel disease (IBD)-like phenotype with NonAlcoholic Fatty liver Disease (NAFLD) yet the mechanisms remain unknown. The present study identifies high mobility
Autor:
Jia Li, Anna Mae Diehl, Baojun Zhang, Deepthi Rajagopalan, Sandeep S. Dave, Cassandra Love, Anupama Reddy, Shibo Li, Yuan Zhuang, Young Mi Kim, Sumedha Roy
Publikováno v:
The Journal of Immunology. 198:3136-3148
Inhibitor of DNA binding (Id) proteins, including Id1–4, are transcriptional regulators involved in promoting cell proliferation and survival in various cell types. Although upregulation of Id proteins is associated with a broad spectrum of tumors,
Autor:
Gregory A. Michelotti, Wolfgang Liedtke, Mitzi Nagarkatti, Saurabh Chatterjee, Firas Alhasson, Varun Chandrashekaran, Prakash S. Nagarkatti, P. Darwin Bell, Ratanesh Seth, Diptadip Dattaroy, Suvarthi Das, Anna Mae Diehl
Publikováno v:
Free Radical Biology and Medicine. 102:260-273
NAFLD is a clinically progressive disease with steatosis, inflammation, endothelial dysfunction and fibrosis being the stages where clinical intervention becomes necessary. Lack of early biomarkers and absence of a FDA approved drug obstructs efforts
Autor:
Cristina Gasparetto, Louis F. Diehl, Keith M. Sullivan, Nelson J. Chao, Anna Mae Diehl, Mustafa R. Bashir, Kristi Romero, Taewoong Choi, Gwynn D. Long, Anthony D. Sung, Sin-Ho Jung, Mitchell E. Horwitz, Stefanie Sarantopoulos, Richard D. Lopez, Yi Ren, Ko K. Maung, Kelly Corbet, David A. Rizzieri, Mohammad Chaudhry
Publikováno v:
Blood. 134:5731-5731
Introduction: Allogeneic hematopoietic stem cell transplant (allo-HCT) remains the only curative treatment for many hematologic conditions. However, significant mortality risk and risk of severe graft-vs-host disease (GvHD) limit its usefulness. Some
Autor:
Guido Ferrari, Audrey Lan, Marzena Swiderska-Syn, Susanna Naggie, Anna Mae Diehl, Sam Lusk, Wing-Kin Syn, Cynthia D. Guy, Steve S. Choi
Publikováno v:
Open Forum Infectious Diseases
Liver disease is a leading cause of HIV-related mortality. Hepatitis C virus (HCV)–related fibrogenesis is accelerated in the setting of HIV coinfection, yet the mechanisms underlying this aggressive pathogenesis are unclear. We identified formalin
Autor:
Ashutosh Kumar, Suvarthi Das, José E. Manautou, Maria B. Kadiiska, Anna Mae Diehl, Gregory A. Michelotti, Saurabh Chatterjee, Ratanesh Seth, Anindya Chanda
Publikováno v:
Toxicology and Applied Pharmacology. 274:42-54
Environmental toxins induce a novel CYP2E1/leptin signaling axis in liver. This in turn activates a poorly characterized innate immune response that contributes to nonalcoholic steatohepatitis (NASH) progression. To identify the relevant subsets of T
Publikováno v:
Mayo Clinic Proceedings. 89:120-130
Cirrhosis and liver cancer, the main causes of liver-related morbidity and mortality, result from defective repair of liver injury. This article summarizes rapidly evolving knowledge about liver myofibroblasts and progenitors, the 2 key cell types th
Autor:
Maria B. Kadiiska, Suvarthi Das, Saurabh Chatterjee, Anna Mae Diehl, Ratanesh Seth, Ashutosh Kumar, Gregory A. Michelotti
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 305:G950-G963
Recent studies indicate that metabolic oxidative stress, autophagy, and inflammation are hallmarks of nonalcoholic steatohepatitis (NASH) progression. However, the molecular mechanisms that link these important events in NASH remain unclear. In this