Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Andres J. Klein-Szanto"'
Autor:
Yuwaraj Kadariya, Andres J. Klein-Szanto, Arti Shukla, Jacqueline Talarchek, Mitchell Cheung, Kathy Q. Cai, Melpo Christofidou-Solomidou, Joseph R. Testa, Craig W. Menges, Ralph A. Pietrofesa, Brooke T. Mossman
Publikováno v:
Cancer Prevention Research. 9:406-414
Exposure to asbestos is causally associated with the development of malignant mesothelioma, a cancer of cells lining the internal body cavities. Malignant mesothelioma is an aggressive cancer resistant to all current therapies. Once inhaled or ingest
Autor:
Andres J. Klein-Szanto, Catherine Healy, Sarah A. Tursi, Christine McCauley, R. Paul Wilson, Steven G. Biesecker, Mark Goulian, Çagla Tükel, Gertrude O. Oppong, Glenn J. Rapsinski
Publikováno v:
NPJ Biofilms and Microbiomes
A disruption of epithelial barrier function can lead to intestinal inflammation. Toll-like receptor (TLR) 2 activation by microbial products promotes intestinal epithelial integrity and overall gut health. Several bacterial species, including enteric
Autor:
Ricardo Garcia, Susana Minguet, Teresa Osteso-Ibánez, Ana Cerezo, Teijo Pellinen, Paloma Sánchez-Mateos, Andres J. Klein-Szanto, Patricia J. Keely, Asier Echarri, Rafael Samaniego, Miguel A. del Pozo, Inmaculada Navarro-Lérida, Enrique Calvo, Jacky G. Goetz, Juan José Lazcano, Edna Cukierman, M. J. Tello
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
eLife
instname
eLife
Marta Tello...et al.
Mechanotransduction is a key determinant of tissue homeostasis and tumor progression. It is driven by intercellular adhesions, cell contractility, and forces generated within the microenvironment and is dependent on extracel
Mechanotransduction is a key determinant of tissue homeostasis and tumor progression. It is driven by intercellular adhesions, cell contractility, and forces generated within the microenvironment and is dependent on extracel
Autor:
Ju Seog Lee, Todd J. Waldron, J. Alan Diehl, Anil K. Rustgi, Albert B. Reynolds, Robert H. Vonderheide, Jiri Kalabis, Ben Rhoades, Douglas B. Stairs, Andres J. Klein-Szanto, Maria E. Vega, Lauren J. Bayne, Jonathan P. Katz
Publikováno v:
Cancer Cell. 19(4):470-483
Summaryp120-catenin (p120ctn) interacts with E-cadherin, but to our knowledge, no formal proof that p120ctn functions as a bona fide tumor suppressor gene has emerged to date. We report herein that p120ctn loss leads to tumor development in mice. We
Autor:
Gary W. Falk, Kathryn E. Hamilton, Prasanna M. Chandramouleeswaran, Amanda B. Muir, Yuta Kasagi, Andres J. Klein-Szanto, Medha Sharma, Alain Benitez, Jonathan M. Spergel, Veronique Giroux, Maureen DeMarshall, Kelly A. Whelan, Hiroshi Nakagawa, Joshua Wang
Publikováno v:
Gastroenterology. 154:S-107
Autor:
Claudia D. Andl, Anil K. Rustgi, Andres J. Klein-Szanto, Douglas B. Stairs, Jiri Kalabis, Hiroshi Nakagawa, Cameron N. Johnstone, Wafik S. El-Deiry, Takaomi Okawa, Edna Cukierman, Carmen Z. Michaylira, Meenhard Herlyn
Publikováno v:
Genes & Development. 21:2788-2803
Esophageal cancer is a prototypic squamous cell cancer that carries a poor prognosis, primarily due to presentation at advanced stages. We used human esophageal epithelial cells as a platform to recapitulate esophageal squamous cell cancer, thereby p
Autor:
Shoji Natsugoe, Mariusz A. Wasik, Andres J. Klein-Szanto, Yan Li, Zihai Li, Anil K. Rustgi, J. Alan Diehl, Yoshiaki Kita, Yi Yang, Nilesh Chitnis, Hiroshi Nakagawa
Publikováno v:
Cancer discovery. 5(3)
Protein arginine methyltransferase 5 (PRMT5) has been implicated as a key modulator of lymphomagenesis. Whether PRMT5 has overt oncogenic function in the context of leukemia/lymphoma and whether it represents a therapeutic target remains to be establ
Publikováno v:
Cancer Letters. 162:161-165
Murine and human skin express an abundance of lipoxygenase isoforms whose functions are not understood. Substantial data have implicated a role for the 'platelet-type' 12-lipoxygenase (P-12LO) metabolite, 12(S)-hydroxy-eicosatetraenoic acid (12-HETE)
Autor:
Melpo Christofidou-Solomidou, Joseph R. Testa, Craig W. Menges, Qi Cai, Arti Shukla, Jacqueline Talarchek, Yuwaraj Kadariya, Brooke T. Mossman, Andres J. Klein-Szanto, Ralph A. Pietrofesa
Publikováno v:
Cancer Research. 76:842-842
Exposure to asbestos is causally associated with the development of malignant mesothelioma (MM), a cancer of cells lining the internal body cavity. MM is an aggressive cancer that is resistant to all current therapies. Once inhaled or ingested, asbes
Publikováno v:
Journal of Neuro-Oncology. 24:143-152
A novel magnetic microsphere-methotrexate (MM-MTX) drug delivery system was synthesized and evaluated in rats bearing rat glioma-2 (RG-2) tumors. Methotrexate was linked to the surface of the magnetic particle via an aminohexanol linker that would re