Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Xi Yang"'
Autor:
Abdelilah S. Gounni, Chunyan Zhang, Sudhanshu Shekhar, Lianyu Shan, Ying Peng, Sai Qiao, Rony Thomas, Shuhe Wang, Xi Yang, Hesam Movassagh, Jie Yang
Publikováno v:
The Journal of Immunology. 206:1251-1265
Recent studies have identified semaphorin 3E (Sema3E) as a novel mediator of immune responses. However, its function in immunity to infection has yet to be investigated. Using a mouse model of chlamydial lung infection, we show that Sema3E plays a si
Autor:
Hong Bo Ye, Qian Wang, Paras S. Minhas, Swapnil Mehta, Edward N. Wilson, Mehrdad Shamloo, Xi Yang, Joshua D. Rabinowitz, Jing Wang, Samuel Yang, Stephanie Tran, Rachel K. Lam, Christoph Mueller, Emily M. Johnson, Ling Liu, Michelle L. James, Michelle S. Swarovski, Katrin I. Andreasson, Qingkun Liu
Publikováno v:
Nature Immunology. 20:1023-1034
Stroke is a multiphasic process in which initial cerebral ischemia is followed by secondary injury from immune responses to ischemic brain components. Here we demonstrate that peripheral CD11b+CD45+ myeloid cells magnify stroke injury via activation
Autor:
Antony George Joyee, Shuhe Wang, Jie Yang, Xi Yang, Weiming Zhao, Hong Bai, Xiaoling Gao, Lei Zhao
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2019 (2019)
Mediators of Inflammation, Vol 2019 (2019)
Chlamydia pneumoniae(Cpn) infection causes multiple acute and chronic human diseases. The role of DCs in host defense against Cpn infection has been well documented. The same is true for invariant natural killer T (iNKT) cells and NK cells, but the i
Autor:
Yi Wang, Xin Ju, Wencan Wu, Wei Wu, Xi Yang, Huaicheng Chen, Zongming Song, Xin Zhang, Jia Qu, Qiufan Tan, Shilong Ying
Publikováno v:
Toxicology Letters. 282:109-120
Retinal ischemia reperfusion (I/R) injury is common in many ophthalmic diseases. Recent studies have shown that toll-like receptor 4 (TLR4) is involved in ischemic retinal injury. Activation of TLRs requires specific accessory proteins such as myeloi
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 312:H1238-H1247
It has been suggested that Toll-like receptor (TLR)4 promotes IL-10-mediated cardiac cell survival, whereas another receptor, TLR2, from the same family, is detrimental. Here, we examined the interactive role of these two innate signaling molecules u
Autor:
Wencan Wu, Xin Zhang, Yang Bian, Yi Wang, Huaicheng Chen, Guang Liang, Zongming Song, Xi Yang, Gaozhi Chen, Jian-Jian Tao, Luqing Ren
Publikováno v:
Toxicology and Applied Pharmacology. 317:1-11
Retinal ischemia-reperfusion (I/R) injury is a common pathological process in many eye disorders. Oxidative stress and inflammation play a role in retinal I/R injury. Recent studies show that toll-like receptor 4 (TLR4) is involved in initiating ster
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 2, p e1009295 (2021)
PLoS Pathogens, Vol 17, Iss 2, p e1009295 (2021)
To date, no reports have linked the multifunctional protein, staphylococcal nuclease domain-containing protein 1 (SND1), to host defense against intracellular infections. In this study, we investigated the role and mechanisms of SND1, by using SND1 k
Publikováno v:
Molecular Neurobiology. 54:4292-4302
Caspase family has been recognized to be involved in dopaminergic (DA) neuronal death and to exert an unfavorable role in Parkinson's disease (PD) pathology. Our previous study has revealed that caspase-1, as an important component of NLRP3 inflammas
Publikováno v:
Molecular Medicine. 19:346-356
An association between inducible costimulator ligand (ICOS-L) expression and interleukin (IL)-10 production by dendritic cells (DCs) has been commonly found in infectious disease. DCs with higher ICOS-L expression and IL-10 production are reportedly
Publikováno v:
International Immunology. 23:239-249
Inducible co-stimulator ligand (ICOSL) is a rather newly defined co-stimulatory molecule, which, through interaction with ICOS expressed on T cells, plays an important role in T-cell activation, differentiation and function. T(h)2-type immune respons