Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Won-Ha Lee"'
Publikováno v:
Inflammation Research. 60:807-815
BAFF and APRIL, as closely related members of the TNF superfamily, are important regulators of B-cell survival. They share two receptors, TACI and BCMA, and BAFF can stimulate an additional receptor, BAFF-R. Although these molecules have been under i
Publikováno v:
Cellular Immunology. 271:157-162
Although Fas is known to be an apoptosis triggering molecule, accumulating studies indicate that Fas has non-apoptotic functions in certain cases. In an effort to identify the role of Fas in macrophage function, the human macrophage-like cell line TH
Publikováno v:
Inflammation. 35:1-10
FasL is a member of the tumor necrosis factor (TNF) superfamily involved in the various immune reactions such as activation-induced cell death, cytotoxic effector function, and establishment of immune privileged sites through its interaction with Fas
Publikováno v:
Cellular Immunology. 256:92-98
The molecular action mechanism of MRP, one of the protein kinase C (PKC) substrates, has been under intense investigation, but reports on its role in macrophage function remain controversial. The treatment of macrophage cell lines with bacterial lipo
Autor:
Kyoungho Suk, Eun-Mi Bae, Joo Y. Lee, Byoung S. Kwon, Hyung-Uk Bae, Won-Ha Lee, Su-Hyung Hong, Yoon-Joong Kang, Won-Jung Kim, Jeong-Euy Park
Publikováno v:
Immunology. 119:421-429
Glucocorticoid-induced tumour necrosis factor receptor family related protein (GITR) is the 18th member of the tumour necrosis factor receptor superfamily (TNFRSF18) and is known to interact with its cognate ligand GITRL (TNFSF18). We investigated th
Autor:
Won-Ha Lee, Won-Jung Kim, Yong Bok Park, Hyung-Uk Bae, Yoon-Joong Kang, Byoung S. Kwon, Dong-Ik Kim, Jeong-Euy Park
Publikováno v:
Cytokine. 29:229-235
TL1A (VEGI/TNFSF15) is the ligand for DR3 (TNFRSF12) and is a newly identified member of the tumor necrosis factor superfamily (TNFSF). Previously, DR3 has been shown to have a role in atherogenesis through stimulation of matrix degrading enzymes inc
Autor:
Won-Jung Kim, Dong-Ik Kim, Yong Bok Park, Dong-Kyun Woo, Yoon-Joong Kang, Byoung S. Kwon, Yoon Lee, Jeong-Euy Park, Se-Hwa Kim, Won-Ha Lee
Publikováno v:
Circulation Journal. 68:396-399
The expression of TWEAK (TNFSF12) and TweakR/Fn14 was detected in regions rich in macrophage/foam cells in atherosclerotic plaques. The role of TWEAK in monocytes in relation to atherogenesis was investigated by analyzing the cellular events induced
Publikováno v:
Cellular immunology. 285(1-2)
LIGHT is a type II transmembrane protein belonging to the TNF superfamily which is involved in co-stimulation of T cells or apoptosis in tumors. In this study, the possibility of LIGHT-mediated reverse signaling was tested in the human monocytic leuk
Autor:
In San Kim, Won Jung Kim, Kyoungho Suk, Seung Beom Park, Sang-Min Lee, Sung Tak Jeon, Byoung S. Kwon, Won-Ha Lee, Beom K. Choi, Eun Mi Choi, Seunghee Lee, Min Young Lee
Publikováno v:
Immunology and cell biology. 88(2)
Most members of the tumor-necrosis factor superfamily have been reported to mediate reverse signaling in T cells, macrophages, and/or dendritic cells. BAFF has been reported to have important functions in B-cell survival through forward signaling, bu
Autor:
Beom K. Choi, Kyoungho Suk, Jeong-Euy Park, Eun Mi Bae, Won Young Kim, Won-Jung Kim, Won-Ha Lee, Eun Mi Choi, Byoung S. Kwon, Young Mo Kang
Publikováno v:
Molecular immunology. 45(2)
Glucocorticoid-induced TNF receptor family related protein ligand (GITRL) is known to interact with its cognate receptor GITR. In order to investigate the potential role of GITRL in the pro-inflammatory activation of macrophages and the signaling pat