Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Angelo M. De Marzo"'
Autor:
David Lim, Mindy K. Graham, Eva Corey, Tamara L. Lotan, Jonathan I. Epstein, Alan K. Meeker, Christopher M. Heaphy, Hao Wang, Mario A. Eisenberger, Angelo M. De Marzo, Christine Davis, Michael C. Haffner
Publikováno v:
Hum Pathol
BACKGROUND: Small cell neuroendocrine carcinoma (SCNC) of the prostate is an aggressive subtype with frequent TP53 mutation and RB1 inactivation, however the molecular phenotype remains an area of investigation. Here, we compared telomere lengths in
Autor:
Alan K. Meeker, William G. Nelson, Charles G. Drake, Srinivasan Yegnasubramanian, George J. Netto, David M. Esopi, Liana B. Guedes, Jun Luo, Kunhwa Kim, Michael C. Haffner, Tamara L. Lotan, Angelo M. De Marzo, Harrison Tsai, Gunes Guner, Doreen N. Palsgrove, Diana Taheri, Rajni Sharma, Arul M. Chinnaiyan, Rohit Mehra, Qizhi Zheng, Emmanuel S. Antonarakis
Publikováno v:
The American Journal of Pathology. 188:1478-1485
Antibodies targeting the programmed cell death protein 1/programmed death-ligand 1 (PD-L1) interaction have shown clinical activity in multiple cancer types. PD-L1 protein expression is a clinically validated predictive biomarker of response for such
Autor:
Angelo M. De Marzo, Tamara L. Lotan, Jessica Hicks, Carlos L. Morais, Alexander S. Baras, Liana B. Guedes
Publikováno v:
Human Pathology. 55:117-125
High-grade prostatic intraepithelial neoplasia (HGPIN) is widely believed to represent a precursor to invasive prostatic adenocarcinoma. However, recent molecular studies have suggested that retrograde spread of invasive adenocarcinoma into pre-exist
Autor:
Tamara L. Lotan, Howard I. Scher, Anuradha Gopalan, Jonathan Melamed, Lawrence D. True, Samson W. Fine, Helen Fedor, Peng Lee, Angelo M. De Marzo, Bruce J. Trock, Bora Gurel, Jessica Hicks, Carlos L. Morais, Beatrice S. Knudsen, Liana B. Guedes
Publikováno v:
Archives of pathologylaboratory medicine. 143(3)
Context.— Phosphatase and tensin homolog (PTEN) is a promising prognostic and potentially predictive biomarker in prostate cancer. Objective.— To assess the effects of preanalytic variables on an analytically validated and fully automated PTEN im
Autor:
J Stephen Nix, Fausto J. Rodriguez, Jaishri O. Blakeley, Michael C. Haffner, Eric H. Raabe, Sama Ahsan, Jessica L. Hicks, Angelo M. De Marzo
Publikováno v:
Journal of neuropathology and experimental neurology. 77(10)
Malignant peripheral nerve sheath tumors (MPNST) are aggressive spindle cell neoplasms that may occur sporadically, often in association with radiation exposure, or in the clinical context of Neurofibromatosis type 1. MPNST are known to harbor geneti
Publikováno v:
The American journal of surgical pathology. 42(10)
Prostatic adenocarcinoma with focal pleomorphic giant cell features is rare with the only prior series consisting of 6 cases. From 2005 to 2018, we identified 29 cases from our consult service and 1 case from our own institution. Men ranged in age fr
Autor:
Jeong S. Han, Michael S. Nagar, Ming Zhou, Angelo M. De Marzo, Ann E. Anderson, Rajal B. Shah, Jennifer Gordetsky, Cristina Magi-Galluzzi, Jessica Hicks, Jonathan I. Epstein, Tamara L. Lotan, Stephen J. Lee, Carlos L. Morais
Publikováno v:
American Journal of Surgical Pathology. 39:169-178
Intraductal carcinoma of the prostate and high-grade prostatic intraepithelial neoplasia (PIN) have markedly different implications for patient care but can be difficult to distinguish in needle biopsies. In radical prostatectomies, we demonstrated t
Publikováno v:
International journal of experimental pathology. 98(4)
Identification of genes specifically deregulated in prostate adenocarcinoma may lead to discovery of new oncogenes/tumour suppressors with clinical relevance for diagnosis, prognosis and/or therapy. CXXC5 is a gene encoding a retinoid-inducible nucle
Autor:
Berrak Gumuskaya, Angelo M. De Marzo, Jonathan I. Epstein, Brian D. Robinson, Tamara L. Lotan, Jessica Hicks, Tsuyoshi Iwata, Hameed A. Rahimi
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Intraductal carcinoma of the prostate is a marker of aggressive disease. However, intraductal carcinoma exists on a morphologic continuum with high grade prostatic intraepithelial carcinoma (PIN) and distinguishing intraductal carcinoma from PIN is a
Autor:
Angelo M. De Marzo, Russell Vang, Robert B. Jenkins, Fusheng Lan, Stephanie R. Fink, Ashley Cimino-Mathews, Saraswati Sukumar, Hind Nassar, Pedram Argani, Aatur D. Singhi, Jessica Hicks, John H. Fetting
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
In breast cancer, amplification of MYC is consistently observed in aggressive forms of disease and correlates with poor prognosis and distant metastases. However, to date, a systematic analysis of MYC amplification in metastatic breast cancers has no