Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sun, Jin"'
Autor:
Christopher J. Logothetis, Joseph E. Busby, Marva Maya, Toru Nakamura, Sertac Yazici, Isaiah J. Fidler, Junqin He, Kim Anh Do, Xuemei Wang, Sun Jin Kim, Dominic Fan, Hisanori Uehara, Paul Mathew
Publikováno v:
JNCI: Journal of the National Cancer Institute. 98:783-793
Background: Inhibiting phosphorylation of platelet-derived growth factor receptor (PDGFR) by treatment with the PDGFR kinase inhibitor imatinib and the chemotherapeutic agent paclitaxel reduces the incidence and size of human prostate cancer bone les
Autor:
Monique B. Nilsson, Kenji Yokoi, Rachel Tsan, Sun Jin Kim, Junqin He, Isaiah J. Fidler, Sertac Yazici, Anil K. Sood, Premal H. Thaker
Publikováno v:
Clinical Cancer Research. 11:4923-4933
Purpose: We determined whether the administration of the tyrosine kinase inhibitor, AEE788, which targets the epidermal growth factor receptor and the vascular endothelial growth factor receptor, alone or in combination with paclitaxel, can inhibit p
Autor:
Junquin He, Isaiah J. Fidler, Paul Mathew, Sun Jin Kim, Sertac Yazici, Robert R. Langley, Hisanori Uehara, Dominic Fan
Publikováno v:
Cancer research. 65(9)
Prostate cancer cells metastasize to the bone where their interaction with osteoclasts and osteoblasts can lead to alterations in the structure of the bone. We determined whether the systemic administration of the bisphosphonate, zoledronate, could p
Autor:
Robert R. Langley, Dominic Fan, Isaiah J. Fidler, Robert B. Rebhun, Rachel Tsan, Sun Jin Kim, Junqin He
Publikováno v:
Cancer research. 64(11)
The activation of the microvascular endothelial cell platelet-derived growth factor (PDGF) receptor (PDGF-R) by PDGF has been implicated in neoplastic angiogenesis. Here, we established cultures of murine bone microvascular endothelial cells and exam
Autor:
Dominic Fan, Hisanori Uehara, Christopher J. Logothetis, Isaiah J. Fidler, Sun Jin Kim, Paul Mathew, David L. Shepherd, Takashi Karashima, Rachel Tsan, Jerald J. Killion
Publikováno v:
Journal of the National Cancer Institute. 95(6)
BACKGROUND Expression of platelet-derived growth factor (PDGF) and activation (by autophosphorylation) of its receptor (PDGF-R), a tyrosine kinase, are associated with the growth of metastatic prostate tumor cells in the bone parenchyma. The tyrosine
Autor:
Sun-Jin, Kim, Hisanori, Uehara, Takashi, Karashima, David L, Shepherd, Jerald J, Killion, Isaiah J, Fidler
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 9(3)
We determined whether blockade of the epidermal growth factor receptor (EGF-R) signaling pathway by oral administration of the EGF-R tyrosine kinase inhibitor (PKI 166) alone or in combination with injectable Taxol inhibits the growth of PC-3MM2 huma
Autor:
Samuel F, Huang, Sun-Jin, Kim, Anh T, Lee, Takashi, Karashima, Cora, Bucana, Daniel, Kedar, Paul, Sweeney, Badar, Mian, Dominic, Fan, David, Shepherd, Isaiah J, Fidler, Colin P, Dinney, Jerald J, Killion
Publikováno v:
Cancer research. 62(20)
We evaluated whether treatment of orthotopic human prostate cancer in nude mice with pegylated IFN-alpha-2b (PEG-IFN-alpha-2b) and docetaxel could represent a two-compartment targeting of primary tumor (tumor cells and tumor-associated endothelial ce