Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Laura Lazo"'
Autor:
Laura Lazo, Monica Bequet-Romero, Gilda Lemos, Alexis Musacchio, Ania Cabrales, Andy J. Bruno, Luis Ariel Espinosa, Markku Saloheimo, Marika Vitikainen, Amalia Hernández, Mark Emalfarb, Ronen Tchelet, Edith Suzarte, Gerardo Guillén
Publikováno v:
Lazo, L, Bequet-Romero, M, Lemos, G, Musacchio, A, Cabrales, A, Bruno, A J, Ariel Espinosa, L, Saloheimo, M, Vitikainen, M, Hernández, A, Emalfarb, M, Tchelet, R, Suzarte, E & Guillén, G 2022, ' A recombinant SARS-CoV-2 receptor-binding domain expressed in an engineered fungal strain of Thermothelomyces heterothallica induces a functional immune response in mice ', Vaccine, vol. 40, no. 8, pp. 1162-1169 . https://doi.org/10.1016/j.vaccine.2022.01.007
Vaccine
Vaccine
Since the beginning of the COVID-19 pandemic, the development of effective vaccines against this pathogen has been a priority for the scientific community. Several strategies have been developed including vaccines based on recombinant viral protein f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6b4676512e1c3ec90c66b344e1ed72
https://cris.vtt.fi/en/publications/4fad051f-5c73-4ba6-bf06-b46a09dfb115
https://cris.vtt.fi/en/publications/4fad051f-5c73-4ba6-bf06-b46a09dfb115
Autor:
Yadira Rodríguez, Enma Brown, Gerardo Guillén, Laura Lazo, Ernesto Marcos, Yusleidi Pérez, Iris Valdés, Melyssa Yaugel, Karem Cobas, Lisset Hermida, Edith Suzarte, Lázaro Gil
Publikováno v:
Archives of Virology. 162:2247-2256
Tetra DIIIC is a subunit vaccine candidate based on domain III of the envelope protein and the capsid protein of the four serotypes of dengue virus. This vaccine preparation contains the DIIIC proteins aggregated with a specific immunostimulatory oli
Autor:
María G. Guzmán, Gerardo Guillén, Laura Lazo, Enma Brown, Yusleydis Pérez, Lisset Hermida, Iris Valdés, Ernesto Marcos, Alienys Izquierdo, Edith Suzarte, Angélica García, Yaremis Romero, Lázaro Gil
Publikováno v:
Bionatura. 1:6-12
The Cuban dengue vaccine program relies on the subunit vaccine based on two specific viral regions: the domain III of the envelope protein and the capsid protein. Previously, we reported the immunogenicity and protection capacity in mice and monkeys
Autor:
Gerardo Enrique Guillen Nieto, Lázaro Gil González, Yusleidi Pérez Fuentes, Iris Valdes Prado, Melyssa Yaugel Novoa, Ernesto Marcos López, Lázaro Cervetto de Armas, Edith Suzarte Portal, Laura Lazo Vazquez, Enma Brown Richards, Lisset Hermida Cruz, Karem Cobas Acosta, Yaremis Romero Fernández
Publikováno v:
Viral immunology. 30(5)
Our group has developed a subunit vaccine candidate against Dengue virus (DENV) based on two different viral regions, the domain III of the envelope protein and the capsid protein. The chimeric proteins for each serotype (DIIIC1-4), aggregated with t
Autor:
Iris Valdés, Lázaro Gil, Thomas Kariuki, Edith Suzarte, Laura Lazo, Ernesto Marcos, Alienys Izquierdo, Guadalupe Guzmán, Peris Ambala, Gerardo Guillén, Lucy Ochola, Lisset Hermida
Publikováno v:
Virology. :70-76
The role of cellular immune response in dengue virus infection is not yet fully understood. Only few studies in murine models propose that CD8+ T-cells are associated with protection from infection and disease. At the light of recent reports about th
Autor:
Mayling Alvarez, Lisset Hermida Cruz, Edith Suzarte, Gerardo Guillén, María G. Guzmán, Iris Valdés, Lázaro Gil, Alienys Izquierdo, Laura Lazo, Ernesto Marcos, Yaremis Romero
Publikováno v:
Microbiology and Immunology. 58:219-226
A dengue vaccine must induce protective immunity against the four serotypes of the virus. Our group has developed chimeric proteins consisting of the protein P64k from Neisseria meningitidis and the domain III from the four viral envelope proteins. I
Autor:
María G. Guzmán, Lázaro Gil, Lisset Hermida, Laura Lazo, Aracelys Blanco, Alequis Pavón, Gerardo Guillén, Yaremis Romero, Carlos López, Iris Valdés
Publikováno v:
Acta Tropica. 124:107-112
In previous studies we reported the cloning, expression and purification of the capsid protein from Dengue-2 virus. Subsequently, we described an in vitro-assembly process for the capsid protein, which resulted in nucleocapsid-like particles (recNLPs
Autor:
Gerardo Guillén, Laura Lazo, Alienys Izquierdo, Ernesto Marcos, Lázaro Gil, Angélica García, Edith Suzarte, María G. Guzmán, Iris Valdés, Lisset Hermida, Enma Brown, Lissandra Méndez
Publikováno v:
Archives of Virology. 158:225-230
It was previously reported that DIIIC-2 (a fusion protein composed of domain III of the envelope protein and the capsid protein from dengue 2 virus), as an aggregate antigen from a partially purified preparation, induced a functional protective immun
Autor:
Mayling Alvarez, Ana B. Pérez, Jorge Martín, Aida Zulueta, María G. Guzmán, Beatriz Sierra, Delfina Rosario, Gerardo Guillén, Rafael Martínez, Laura Lazo, R. Rodríguez, Lisset Hermida, Carlos López, Irina Prado, Lidice Bernardo
Publikováno v:
Vaccine. 24:3165-3171
We have previously reported the construction and evaluation in mice of recombinant fusion proteins formed by a fragment (aa 286-426) of the dengue envelope protein and the P64k protein from Neisseria meningitidis. In this work we describe the immuniz
Autor:
Gerardo Guillén, Lázaro López, Laura Lazo, Yusleydis Pérez, Alienys Izquierdo, Ernesto Marcos, Jorge Fernandez de Castro, María G. Guzmán, Maylin Álvarez, Lázaro Gil, Iris Valdés, Lisset Hermida, Edith Suzarte, Angélica García, Yaremis Romero
Publikováno v:
International immunology. 27(8)
Our group developed a subunit vaccine candidate against dengue virus based on two different viral regions: the domain III of the envelope protein and the capsid protein. The novel chimeric protein from dengue-2 virus [domain III-capsid (DIIIC-2)], wh