Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Julia Jellusova"'
Autor:
Melanie Boerries, Sebastian N. Steiner, Michael Reth, Bernd Wollscheid, Jonas B. Albinus, Reinhard E. Voll, Kathrin Kläsener, Marco Cavallari, Julia Jellusova, Geoffroy Andrieux, Ulrich Salzer, Beatrix Süß, Chiara Böhler
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 118 (7)
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
CD20 is a B cell-specific membrane protein and represents an attractive target for therapeutic antibodies. Despite widespread usage of anti-CD20 antibodies for B cell depletion therapies, the biological function of their target remains unclear. Here,
Autor:
Kathrin Kläsener, Geoffroy Andrieux, Julia Jellusova, Michael Reth, Bernd Wollscheid, Chiara Boehler, Reinhard E. Voll, Beatrix Suess, Ulrich Salzer, Jonas B Albinus, Sebastian N Steiner, Marco Cavallari, Melanie Boerries
CD20 is a B cell specific membrane protein and a target of therapeutic antibodies such as rituximab (RTX). In spite of the prominent usage of anti-CD20 antibodies in the clinic little is known about the biological function of CD202. Here we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2182b8137422d9d1685dd21328c54193
https://doi.org/10.1101/2020.07.31.230110
https://doi.org/10.1101/2020.07.31.230110
Autor:
Ana V. Miletic, Mark J. Shlomchik, Wai-Wai Lin, Robert C. Rickert, Julia Jellusova, Matthew H. Cato, Yinling Hu, Gail A. Bishop
Publikováno v:
Cell Reports, Vol 5, Iss 4, Pp 1022-1035 (2013)
SummaryBAFF is a soluble factor required for B cell maturation and survival. BAFF-R signals via the noncanonical NF-κB pathway regulated by the TRAF3/NIK/IKK1 axis. We show that deletion of Ikk1 during early B cell development causes a partial impai
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 184(7)
CD22 and Siglec-G are inhibitory coreceptors for BCR-mediated signaling. Although CD22-deficient mice show increased calcium signaling in their conventional B2 cells and a quite normal B cell maturation, Siglec-G–deficient mice have increased calci