Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Shaad Essa Abdullah"'
Autor:
Song Wu, Matthew D. Hellmann, Han Si, Jean-Charles Soria, Maria Libera Ascierto, Rajiv Raja, Caroline Germa, Nathan Standifer, Chris Morehouse, Carl Barrett, Shaad Essa Abdullah, Marlon Rebelatto
Publikováno v:
Regular and young investigator award abstracts.
Background Despite the encouraging successes of immune checkpoint inhibitors, many patients do not benefit and are either refractory or relapse. The mechanisms of refractory or relapsed disease following PD-(L)1 blockade are largely unknown. To ident
Autor:
Laura C. Collins, Revashnee Naidoo, Sarah Stanhope, Shaad Essa Abdullah, Emma Leach, Adel Benlahrech, Koustubh Ranade, Joseph J. Sacco, Jessica C. Hassel
Publikováno v:
Cancer Research. 81:1673-1673
Background: Tebentafusp, an investigational TCR–anti-CD3 bispecific fusion protein (ImmTAC) that targets gp100 and activates T cells, has shown monotherapy activity in metastatic melanoma [1-3]. In a phase I/II trial enrolling metastatic uveal mela
Autor:
Brandon W. Higgs, Koustubh Ranade, Mohammed M. Dar, Chen Gao, Shaad Essa Abdullah, Chris Morehouse
Publikováno v:
Journal of Clinical Oncology. 37:2563-2563
2563 Background: Treatment with ICIs can manifest immune-related adverse events (irAEs), which have correlated with clinical outcomes in certain tumors. However, timing of these events and how early irAEs correlate with outcomes is unclear. We assess
Autor:
Rajiv Raja, Natasha Angra, Philip Brohawn, Brandon W. Higgs, Sriram Sridhar, Michael Kuziora, Chris Morehouse, Koustubh Ranade, Shaad Essa Abdullah
Publikováno v:
Journal of Clinical Oncology. 36:51-51
51 Background: Associations between early reduction in plasma ctDNA, pretreatment tumoral IFNγ sig, liver metastases and outcomes, and between tumor mutational burden (TMB) and CD274 (PD-L1) mRNA or IFNγ sig in TCGA were evaluated in NSCLC and UC p