Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sarah MacPherson"'
Autor:
Lauren G. Zacharias, Phineas T. Hamilton, John Stagg, Gillian Carleton, Peter H. Watson, Ryan D. Sheldon, Julian J. Lum, Sarah MacPherson, Ralph J. DeBerardinis, Sarah Keyes, Kelsey S. Williams, Bertrand Allard, Elaine Y. Liu, Julian Smazynski, Brenna Pauly, Russell G. Jones, Abigail E. Ellis, Marisa Kilgour, Brad H. Nelson
Publikováno v:
Science Advances
MNA contributes to the immune suppression of T cells and represents a potential immunotherapy target to treat human cancer.
Immune regulatory metabolites are key features of the tumor microenvironment (TME), yet with a few exceptions, their iden
Immune regulatory metabolites are key features of the tumor microenvironment (TME), yet with a few exceptions, their iden
Autor:
Marisa Kilgour, Sarah MacPherson, Bertrand Allard, Sarah Keyes, Phineas T. Hamilton, Julian Lum, Ralph J. DeBerardinis, John Stagg, Julian Smazynski, Peter Watson, Lauren G. Zacharias, Bradley Nelson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Immune regulatory metabolites are key features of the tumor microenvironment (TME), yet with a few exceptions, their identities remain largely unknown. Importantly, little is known about the heterogeneity of metabolites that are present or
Autor:
Bertrand Allard, Peter H. Watson, Brenna Pauly, Brad H. Nelson, John Stagg, Phineas T. Hamilton, Lauren G. Zacharias, Julian J. Lum, Ralph J. DeBerardinis, Julian Smazynski, Sarah MacPherson, Sarah Keyes, Marisa Kilgour
Immune regulatory metabolites are key features of the tumor microenvironment (TME), yet with a few notable exceptions, their identities remain largely unknown. We uncovered the immune regulatory metabolic states and metabolomes of sorted tumor and st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ff7c0d6fedd6fff3ab6eb5c186f283
Autor:
Mary A. Elrick, Vincent I. Poon, Jillian M. Brandon, Luke R. K. Hughson, Ninan Abraham, Katelin N. Townsend, Izabelle Gadawski, Julian J. Lum, E. John Wherry, Sarah MacPherson, Katrin Schlie, Lindsay DeVorkin, Hélène C. F. Côté, Ashley Westerback, Noboru Mizushima
Publikováno v:
The Journal of Immunology. 194:4277-4286
The activation and expansion of effector CD8+ T cells are essential for controlling viral infections and tumor surveillance. During an immune response, T cells encounter extrinsic and intrinsic factors, including oxidative stress, nutrient availabili
Publikováno v:
OncoImmunology. 3:e28272
Tumor-infiltrating lymphocytes (TILs) are crucial for effective antitumor responses. However, hypoxia can skew T-cell differentiation and function, thereby perturbing TILs. We have demonstrated that TILs and their immune function are associated with