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Autor:
Tobias R. Kollmann, Ann-Jay Tong, Brandon J. Thomas, Stephen T. Smale, Kathleen Wee, Michelle M. Lissner
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132061 (2015)
PloS one, vol 10, iss 7
PLoS ONE
PloS one, vol 10, iss 7
PLoS ONE
A variety of age-related differences in the innate and adaptive immune systems have been proposed to contribute to the increased susceptibility to infection of human neonates and older adults. The emergence of RNA sequencing (RNA-seq) provides an opp
Publikováno v:
Clinical and vaccine immunology : CVI. 21(3)
Robust CD8+T cell responses are essential for immune protection against intracellular pathogens. Using parenteral administration of ovalbumin (OVA) protein as a model antigen, the effect of the Toll-like receptor 9 (TLR9) agonist, CpG oligodeoxynucle