Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jan Cerny"'
Publikováno v:
Journal of Thrombosis and Thrombolysis
Coronavirus disease-2019 (COVID-19) is a rapidly evolving health crisis caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is a novel disease entity and we are in a learning phase with regards to the pathogenesis, di
Publikováno v:
Journal of Medical Virology
The current pandemic due to coronavirus disease 2019 (COVID‐19) has posed an unprecedented challenge for the medical communities, various countries worldwide, and their citizens. Severe acute respiratory syndrome coronavirus 2 has been studied for
Publikováno v:
Laboratory Medicine
The COVID-19 pandemic has led to a major setback in both the health and economic sectors across the globe. The scale of the problem is enormous because we still do not have any specific anti-SARS-CoV-2 antiviral agent or vaccine. The human immune sys
Autor:
Christine Hewes, Theofilos Poutahidis, Glennice N. Bowen, Yingwang Liu, Jian Hua Liu, Hanchen Li, Anna M. Cerny, Stephen Lyle, Varada P. Rao, Nathan F. Moore, Xueli Fan, Susan E. Erdman, JeanMarie Houghton, Christine L. Taylor, Jan Cerny, Evelyn A. Kurt-Jones, Erin A. Jackson
Publikováno v:
Stem Cells and Development. 19:1153-1166
Neoplastic epithelia may remain dormant and clinically unapparent in human patients for decades. Multiple risk factors including mutations in tumor cells or the stromal cells may affect the switch from dormancy to malignancy. Gene mutations, includin
Autor:
Benjamin J. Chen, Jan Cerny, Bradley Switzer, Rajneesh Nath, Hongbo Yu, Bruce A. Woda, Katherine Devitt, Muthalagu Ramanathan
Publikováno v:
Leukemia Research Reports
Leukemia Research Reports, Vol 3, Iss 2, Pp 42-45 (2014)
Leukemia Research Reports, Vol 3, Iss 2, Pp 42-45 (2014)
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening clinical syndrome characterized by dysregulation of the immune system. Impaired function of cytotoxic T cells and natural killer cells is often seen, and T-cell malignancies represent mos
Publikováno v:
Immunological reviews. 160
Summary: The immune system of aged mice produces antibodies that are characterized by low affinity, diminished protection against infections and autoreactivity. It has been shown that these antibodies may be encoded by different immunoglobulin V gene
Autor:
Claudio Nicoletti, Jan Cerny
Publikováno v:
Cellular immunology. 144(2)
Antibody response to phosphorylcholine, an immunodominant epitope of Streptococcus pneumoniae R36a (Pn), is characterized by a public idiotype, T15, that is expressed on a large proportion of antibody molecules produced by all mouse inbred strains. T
Publikováno v:
The Journal of Experimental Medicine
The effects of immune complexes on the antibody response of BALB/c mice to Streptococcus pneumoniae R36a (Pn) were investigated. The cell wall polysaccharide (PnC) extracted from Pn was used to form complexes with TEPC-15, a myeloma protein that bind
Publikováno v:
European Journal of Immunology. 10:661-664
Normal BALB/c spleen cells incubated for 2 days with Streptococcus pneumoniae R 36 a (Pn) vaccine in vitro acquired the specific ability to inhibit the T-independent anti-Pn response of fresh lymphocytes. The activated suppressor cells were susceptib
Publikováno v:
The Journal of Experimental Medicine
The role of the thymus in the cyclical appearance of the dominant idiotype of the myeloma protein secreted by the TEPC-15 plasmacytoma (T-15)-bearing plaque-forming cells (PFC) and anti-idiotypic cells (i.e., cells with receptors for T-15) in the spl