Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Mohammed Khan"'
Autor:
Muhammad Alam, Syed Muhammad Mukarram Shah, Syed Uzair Ali Shah, Muslim Raza, Saima Naz, Khalid Mohammed Khan, Umer Rashid, Ajmal Khan, Ghias Uddin, Abdur Rauf
Publikováno v:
South African Journal of Botany. 143:359-362
The study aimed to validate the folkloric medicinal uses of Viburnum grandiflorum. The column chromatography led to the isolation of a compound from the chloroform soluble fraction of V. grandiflorum which was characterized as 2, 3-dihydro-2-(4ʹ-hyd
Autor:
Khan Momin, Iqbal Maryam, Wadood Abdul, Ashfaq Ur Rehman, Ali Mahboob, Rafique Rafaila, Zaman Khair, Alam Aftab, Shah Sana, Mohammed Khan Khalid, Yousaf Muhammad
Publikováno v:
Medicinal Chemistry. 17:903-912
Background: The inhibition of α-amylase enzyme is one of the best therapeutic approach for the management of type II diabetes mellitus. Chalcone possesses a wide range of biological activities. Objective: In the current study chalcone derivatives (1
Autor:
Kanwal, Saurabh Bhatia, Shahnaz Perveen, Akinsola Akande, Sherifat A. Aboaba, Muhammad Taha, Sridevi Chigurupati, Uzma Salar, Shahbaz Shamim, Khalid Mohammed Khan, Muhammad Riaz, Abdul Wadood, Shazia Syed
Publikováno v:
ACS Omega, Vol 6, Iss 35, Pp 22726-22739 (2021)
ACS Omega
ACS Omega
Benzimidazole scaffolds are known to have a diverse range of biological activities and found to be antidiabetic and antioxidant. In this study, a variety of arylated benzimidazoles 1–31 were synthesized. Except for compounds 1, 6, 7, and 8, all are
Autor:
Noor Ul Ain Nawaz, Mehreen Lateef, Shahbaz Shamim, Fayaz Ali, Khalid Mohammed Khan, Abdul Wadood, Muhammad Taha, Uzma Salar, Ashfaq Ur Rehman, Shahnaz Perveen
Publikováno v:
ACS Omega, Vol 6, Iss 24, Pp 15794-15803 (2021)
ACS Omega
ACS Omega
N-Aryl-3,4-dihydroisoquinoline carbothioamide analogues 1-22 were synthesized by a simple one-step reaction protocol and subjected to in vitro urease inhibition studies for the first time. All compounds 1-22 were found active and showed significant t
Autor:
Kanwal, Shahnaz Perveen, Uzma Salar, Khalid Mohammed Khan, Farman Ali, Farwa Naqvi, Shakil Ahmed, Aisha Faheem, Almas Jabeen, Erum Iqbal
Publikováno v:
Medicinal Chemistry. 16:1099-1111
Background: A number of non-steroidal anti-inflammatory drugs (NSAIDs) including aspirin, indomethacin, ibuprofen, flufenamic acid, and phenylbutazone are being clinically used to treat inflammatory disorders. These NSAIDs are associated with serious
Autor:
Fazal Rahim, Nizam Uddin, Syed Adnan Ali Shah, Khalid Mohammed Khan, Muhammad Taha, Mohammed Salahuddin, Ameeduzzafar Zafar, Aftab Ahmad Khan, Syahrul Imran, Zainul Amiruddin Zakaria
Publikováno v:
Arabian Journal of Chemistry, Vol 15, Iss 1, Pp 103505-(2022)
New benzimidazole analogues (1–18) were synthesized and characterized through different spectroscopic techniques such as 1H NMR, 13C NMR and HREI-MS. All analogues were screened for β-glucuronidase inhibitory potential. All analogues showed varied
Autor:
Uzma Salar, Kanwal, Shehryar Hameed, Shahnaz Perveen, Muhammad Ali, Zaheer Ul-Haq, Muhammad Taha, Faiza Seraj, Khalid Mohammed Khan, Ajmal Khan, Ruqaiya Khalil
Publikováno v:
Molecular Diversity. 25:143-157
Novel ibuprofen derivatives 1–19 including ibuprofen hydrazide 1, and substituted thiourea derivatives 2–19 were synthesized and characterized by EI-MS, FAB-MS, HREI-MS, HRFAB-MS, 1H-, and 13C-NMR spectroscopic techniques. The synthetic molecules
Publikováno v:
Medicinal Chemistry. 15:162-174
Background:Inflammation is a biological rejoinder of vascular tissues against destructive agents e.g. irritants, damaged cell or pathogens. During inflammation, respiratory burst occurs by activated phagocytes which help to destroy invading pathogens
Autor:
Khalid Mohammed Khan, Nimra Naveed Shaikh, Sarosh Iqbal, Zaheer Ul-Haq, Shahnaz Perveen, Muhammad Iqbal Choudhary, Sehrish Naz
Publikováno v:
Medicinal Chemistry. 14:818-830
BACKGROUND Glucuronidation is essential for the metabolism and excretion of toxic substances. β-Glucuronidase enzyme slows down the process of glucuronidation, and thus plays an important role in the on-set of colorectal carcinoma, and many other di
Autor:
Almas Jabeen, Nida Dastagir, Tariq Ahmed, Khalid Mohammed Khan, Shahnaz Perveen, Aisha Faheem, Shazia Shah, Shakil Ahmed, Abeer Raza, Arshia, Nida Siraj Kazmi
Publikováno v:
Medicinal Chemistry. 14:674-687
Background Inflammation is defined as the response of immune system cells to damaged or injured tissues. The major symptoms of inflammation include increased blood flow, cellular influx, edema, elevated cellular metabolism, reactive oxygen species (R