Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Tomoaki Ikeda"'
Autor:
Masahiro Nakao, Yukiko Nanba, Asumi Okumura, Junichi Hasegawa, Satoshi Toyokawa, Kiyotake Ichizuka, Naohiro Kanayama, Shoji Satoh, Nanako Tamiya, Akihito Nakai, Keiya Fujimori, Tsugio Maeda, Hideaki Suzuki, Mitsutoshi Iwashita, Akira Oka, Tomoaki Ikeda
Publikováno v:
BJOG: An International Journal of Obstetrics & Gynaecology. 129:1574-1582
To investigate the association between hypoxic-ischaemic insult timing and brain injury type in infants with severe cerebral palsy (CP).Longitudinal study.Database of the Recurrence Prevention Committee, Japan Obstetric Compensation System for Cerebr
Autor:
Junichi Hasegawa, Masahiro Nakao, Tomoaki Ikeda, Satoshi Toyokawa, Emi Jojima, Shoji Satoh, Kiyotake Ichizuka, Nanako Tamiya, Akihito Nakai, Keiya Fujimori, Tsugio Maeda, Satoru Takeda, Hideaki Suzuki, Shigeru Ueda, Mitsutoshi Iwashita, Tsuyomu Ikenoue
Publikováno v:
BMC Pregnancy and Childbirth. 22
Background The aim of the present study was to clarify fetal heart rate (FHR) evolution patterns in infants with cerebral palsy (CP) according to different types of umbilical cord complications. Methods This case–control study included children bor
Autor:
Jenny A. Westgate, Alistair J. Gunn, Christopher A. Lear, Tomoaki Ikeda, Etsuko Miyagi, Antoniya Georgieva, Laura Bennet, Michi Kasai
Publikováno v:
BJOG: An International Journal of Obstetrics & Gynaecology. 128:1433-1442
Objective: Cardiotocography is widely used to assess fetal well‐being during labour. The positive predictive value of current clinical algorithms to identify hypoxia‐ischaemia is poor. In experimental studies, fetal hypotension is the strongest p
Autor:
Michael J. Beacom, Paul P. Drury, Alistair J. Gunn, Joanne O. Davidson, Etsuko Miyagi, Tomoaki Ikeda, Laura Bennet, Michi Kasai, Christopher A. Lear, Yoshiki Maeda
Publikováno v:
The Journal of physiologyReferences. 597(23)
Key points •Therapeutic hypothermia needs to be started as early as possible in the first 6 h after acute injury caused by hypoxia-ischaemia (HI), but the severity and timing of HI are often unclear. In this study we evaluated whether measures of h
Autor:
Kyohei, Yamaguchi, Christopher A, Lear, Michael J, Beacom, Tomoaki, Ikeda, Alistair J, Gunn, Laura, Bennet
KEY POINTS: Fetal heart rate variability is a critical index of fetal wellbeing. Suppression of heart rate variability may provide prognostic information on the risk of hypoxic‐ischaemic brain injury after birth. In the present study, we report the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0f2485780f40f594d17747d2cafec169
https://europepmc.org/articles/PMC6265593/
https://europepmc.org/articles/PMC6265593/
Publikováno v:
Glia
The mechanisms of neuronal injury after hypoxia–ischemia (HI) are different in the immature and the adult brain, but microglia activation has not been compared. The purpose of this study was to phenotype resident microglia and blood‐derived macro
Autor:
Masahiro Hayakawa, Tomoaki Ikeda, Satoshi Suzuki, Keiko Nakanishi, Taiki Kondo, Seiji Kojima, Yuko Ichinohashi, Michiro Yamamoto, Tomomi Kotani, Masahiro Tsuji, Hitoshi Hirata, Yoshiaki Sato, Yuichiro Sugiyama, Klas Blomgren, Tetsuo Hattori, Akihiro Hirakawa
Publikováno v:
Developmental Neuroscience. 37:95-104
This study aimed to investigate whether the administration of mononuclear cells derived from human umbilical cord blood cells (UCBCs) could ameliorate hypoxic-ischemic brain injury in a neonatal rat model. The left carotid arteries of 7-day-old rats
Autor:
Akihiko Taguchi, Masahiro Tsuji, Tomoaki Ikeda, Tomohiro Matsuyama, Yukiko Kasahara, Makiko Ohshima
Publikováno v:
Experimental Neurology. 247:218-225
Neonatal stroke occurs in 1/4000 live births and leaves life-long neurological impairments, such as cerebral palsy and epilepsy. Currently, the rodent models of neonatal stroke that are available exhibit significant inter-animal variability, which ma
Publikováno v:
Experimental Neurology. 233:214-220
Progesterone and its metabolite, allopregnanolone, are neurosteroids that are present at high concentrations in fetal brains that decrease right after birth. Allopregnanolone is a potent positive modulator of γ-aminobutyric acid A (GABA(A)) receptor
Publikováno v:
Neuroscience Letters. 414:5-9
The occurrence of hypoxia-ischemia (HI) during early fetal or neonatal stages of an individual leads to the damaging of immature neurons resulting in behavioral and psychological dysfunctions. Free radical-mediated lipid peroxidation is the main caus