Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Kajantie, Eero"'
Autor:
Kivelä A; Medical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. Electronic address: anni.kivela@helsinki.fi., Heinonen S; Obstetrics and Gynaecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Kivinen K; DeepScan Diagnostics Oy, Helsinki, Finland., Kere J; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden; Stem Cells and Metabolism Research Program, University of Helsinki and Folkhälsan Research Center, Helsinki, Finland., Kajantie E; Clinical Medicine Research Unit, MRC, Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway; Population Health Unit, Finnish Institute for Health and Welfare, Helsinki and Oulu, Finland and Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Jääskeläinen T; Medical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Food and Nutrition, University of Helsinki, Helsinki, Finland., Laivuori H; Medical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Center for Child, Adolescent, and Maternal Health Research, Faculty of Medicine and Health Technology, Tampere University and Department of Obstetrics and Gynecology, Tampere University Hospital, Tampere, Finland; Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Publikováno v:
Pregnancy hypertension [Pregnancy Hypertens] 2023 Dec; Vol. 34, pp. 5-12. Date of Electronic Publication: 2023 Sep 12.
Autor:
Kivioja A; Department of Obstetrics and Gynecology, Tampere University Hospital, Finland (A.K., E.T., H.L.).; Center for Child, Adolescent, and Maternal Health, Faculty of Medicine and Health Technology (A.K., E.T., J.T., H.L.), Tampere University, Finland., Toivonen E; Department of Obstetrics and Gynecology, Tampere University Hospital, Finland (A.K., E.T., H.L.).; Center for Child, Adolescent, and Maternal Health, Faculty of Medicine and Health Technology (A.K., E.T., J.T., H.L.), Tampere University, Finland., Tyrmi J; Center for Child, Adolescent, and Maternal Health, Faculty of Medicine and Health Technology (A.K., E.T., J.T., H.L.), Tampere University, Finland.; Computational Medicine, Faculty of Medicine (J.T.), University of Oulu, Finland.; Center for Life Course Health Research, Faculty of Medicine (J.T.), University of Oulu, Finland.; Biocenter Oulu (J.T.), University of Oulu, Finland., Ruotsalainen S; Institute for Molecular Medicine Finland, Helsinki Institute of Life Science (S. Ruotsalainen, S. Ripatti, K.K., H.L.), University of Helsinki, Finland., Ripatti S; Institute for Molecular Medicine Finland, Helsinki Institute of Life Science (S. Ruotsalainen, S. Ripatti, K.K., H.L.), University of Helsinki, Finland.; Broad Institute of MIT and Harvard, Cambridge, MA (S. Ripatti)., Huhtala H; Faculty of Social Sciences (H.H.), Tampere University, Finland., Jääskeläinen T; Medical and Clinical Genetics (T.J., H.L.), University of Helsinki and Helsinki University Hospital, Finland., Heinonen S; Obsterics and Gynaecology (S.H.), University of Helsinki and Helsinki University Hospital, Finland., Kajantie E; PEDEGO Research Unit, Medical Research Center Oulu, Oulu University Hospital (E.K., A.P.), University of Oulu, Finland.; Children's Hospital (E.K.), University of Helsinki and Helsinki University Hospital, Finland.; Public Health Promotion Unit (E.K.), University of Helsinki and Helsinki University Hospital, Finland.; Department of Clinical and Molecular Medicine, Norwegian University of Health and Technology, Trondheim, Norway (E.K.)., Kere J; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden (J.K.)., Kivinen K; Institute for Molecular Medicine Finland, Helsinki Institute of Life Science (S. Ruotsalainen, S. Ripatti, K.K., H.L.), University of Helsinki, Finland., Pouta A; PEDEGO Research Unit, Medical Research Center Oulu, Oulu University Hospital (E.K., A.P.), University of Oulu, Finland.; Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland., Saarela T; Department of Clinical Genetics, Kuopio University Hospital, Finland (T.S.)., Laivuori H; Center for Child, Adolescent, and Maternal Health, Faculty of Medicine and Health Technology (A.K., E.T., J.T., H.L.), Tampere University, Finland.; Institute for Molecular Medicine Finland, Helsinki Institute of Life Science (S. Ruotsalainen, S. Ripatti, K.K., H.L.), University of Helsinki, Finland.; Medical and Clinical Genetics (T.J., H.L.), University of Helsinki and Helsinki University Hospital, Finland.
Publikováno v:
Hypertension (Dallas, Tex. : 1979) [Hypertension] 2022 Sep; Vol. 79 (9), pp. 2008-2015. Date of Electronic Publication: 2022 Jul 07.
Autor:
Surendran P; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Rutherford Fund Fellow, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Feofanova EV; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Lahrouchi N; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Amsterdam UMC, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences Amsterdam, Amsterdam, the Netherlands., Ntalla I; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Karthikeyan S; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Cook J; Department of Biostatistics, University of Liverpool, Liverpool, UK., Chen L; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Mifsud B; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar., Yao C; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Kraja AT; Division of Statistical Genomics, Department of Genetics and Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA., Cartwright JH; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Hellwege JN; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Giri A; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.; Division of Quantitative Sciences, Department of Obstetrics & Gynecology, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Tragante V; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Thorleifsson G; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Liu DJ; Institute of Personalized Medicine, Penn State College of Medicine, Hershey, PA, USA., Prins BP; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Stewart ID; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Cabrera CP; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Eales JM; Division of Cardiovascular Sciences, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK., Akbarov A; Division of Cardiovascular Sciences, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK., Auer PL; Joseph J Zilber School of Public Health, University of Wisconsin, Milwaukee, WI, USA., Bielak LF; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Braithwaite VS; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.; MRC Nutrition and Bone Health Group, University of Cambridge, Cambridge, UK.; MRC Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, Gambia., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Daw EW; Division of Statistical Genomics, Department of Genetics and Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA., Warren HR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Drenos F; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK., Nielsen SF; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Fauman EB; Internal Medicine Research Unit, Pfizer, Cambridge, MA, USA., Fava C; Department of Medicine, University of Verona, Verona, Italy.; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Ferreira T; The Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK., Foley CN; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; MRC Biostatistics Unit, University of Cambridge, Cambridge, UK., Franceschini N; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Gao H; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK., Giannakopoulou O; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Centre for Genomic Health, Queen Mary University of London, London, UK.; Division of Psychiatry, University College of London, London, UK., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Gudbjartsson DF; deCODE genetics/Amgen, Inc, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland., Guo X; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK., Havulinna AS; Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK.; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Helgadottir A; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Huffman JE; MRC Human Genetics Unit, IGMM, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Hwang SJ; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Boston University and National Heart, Lung and Blood Institute Framingham Heart Study, Framingham, MA, USA., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Centre for Genomic Health, Life Sciences, Queen Mary University of London, London, UK., Kontto J; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Larson MG; Boston University and National Heart, Lung and Blood Institute Framingham Heart Study, Framingham, MA, USA.; Biostatistics Department, Boston University School of Public Health, Boston, MA, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Lindström J; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Lotta LA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Lu Y; The Charles Bronfman Institute for Personalized Medicine at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Mahajan A; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Malerba G; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy., Masca NGD; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Centre, Leicester, UK., Mei H; Department of Data Science, School of Population Health, University of Mississippi Medical Center, Jackson, MS, USA., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands., Mosen-Ansorena D; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, Ludwig-Maximilians-University Munich, Munich, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU, Munich, Germany., Paré G; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Paul DS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK., Perola M; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Clinical and Molecular Metabolism Research Program (CAMM), Faculty of Medicine, University of Helsinki, Helsinki, Finland., Poveda A; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden., Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Richard M; Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Richardson TG; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Sepúlveda N; Department of Infection Biology, Faculty of Tropical and Infectious Diseases, London School of Hygiene & Tropical Medicine, London, UK.; Centre of Statistics and Applications of University of Lisbon, Lisbon, Portugal., Sim X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Saw Swee Hock School of Public Health, National University of, Singapore, Singapore., Smith AV; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Smith JA; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Staley JR; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Stanáková A; University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Sulem P; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Thériault S; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.; Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University, Quebec City, Quebec, Canada., Thorsteinsdottir U; deCODE genetics/Amgen, Inc, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Trompet S; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden., Velez Edwards DR; Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Tennessee Valley Health Systems VA, Nashville, TN, USA., Veronesi G; Research Center in Epidemiology and Preventive Medicine, Department of Medicine and Surgery, University of Insubria, Varese, Italy., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, University Medicine and University of Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Willems SM; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Yao J; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Young R; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK., Yu B; Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA., Zhang W; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK., Zhao JH; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK., Zhao W; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA., Zhao W; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Evangelou E; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Aeschbacher S; Division of Cardiology, University Hospital, Basel, Switzerland., Asllanaj E; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; Department of Epidemiology, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands., Blankenberg S; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany.; University Medical Center Hamburg Eppendorf, Hamburg, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, Hamburg, Germany., Bonnycastle LL; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Brandslund I; Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Braund PS; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Centre, Leicester, UK., Burgess S; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; MRC Biostatistics Unit, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK., Cho K; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Christensen C; Medical Department, Lillebaelt Hospital, Vejle, Denmark., Connell J; University of Dundee, Ninewells Hospital & Medical School, Dundee, UK., Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Dominiczak AF; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, UK., Dörr M; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Eiriksdottir G; Icelandic Heart Association, Kopavogur, Iceland., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.; Department of Population Science and Experimental Medicine, Institute of Cardiovascular Science, University College London, London, UK., Gaziano JM; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Grove ML; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Hallmans G; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Have CT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Heiss G; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Jørgensen ME; Steno Diabetes Center, Copenhagen, Gentofte, Denmark., Jousilahti P; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Kajantie E; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; PEDEGO Research Unit, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Hospital for Children and Adolescents, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland., Kamat M; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK., Käräjämäki A; Department of Primary Health Care, Vaasa Central Hospital, Vaasa, Finland.; Diabetes Center, Vaasa Health Care Center, Vaasa, Finland., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Koistinen HA; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Kovesdy CP; Nephrology Section, Memphis VA Medical Center, Memphis, TN, USA., Kuulasmaa K; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Laatikainen T; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lannfelt L; Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., Lee IT; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan.; School of Medicine, , Chung Shan Medical University, Taichung, Taiwan.; College of Science, Tunghai University, Taichung, Taiwan., Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.; Department of Social Work, Tunghai University, Taichung, Taiwan., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Martin LW; George Washington University School of Medicine and Health Sciences, Washington DC, USA., Moitry M; Department of Public health, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France., Nadkarni G; The Charles Bronfman Institute for Personalized Medicine at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Neville MJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Palmer CNA; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland, UK., Papanicolaou GJ; Epidemiology Branch, NHLBI, Bethesda, MD, USA., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Peters J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Department of Immunology and Inflammation, Imperial College London, London, UK., Poulter N; International Centre for Circulatory Health, Imperial College London, London, UK., Rasheed A; Centre for Non-Communicable Diseases, Karachi, Pakistan., Rasmussen KL; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Rayner NW; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Mägi R; Institute of Genomics, University of Tartu, Tartu, Estonia., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden.; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Rettig R; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute of Physiology, University Medicine Greifswald, Karlsburg, Germany., Rossouw J; Division of Cardiovascular Sciences, NHLBI, Bethesda, MD, USA., Schreiner PJ; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA., Sever PS; National Heart and Lung Institute, Imperial College London, London, UK., Sigurdsson EL; Department of Family Medicine, University of Iceland, Reykjavik, Iceland.; Development Centre for Primary Health Care in Iceland, Reykjavik, Iceland., Skaaby T; Center for Clinical Research and Disease Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark., Sun YV; Department of Epidemiology, Emory University Rollins School of Public Health, Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, USA., Sundstrom J; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Thorgeirsson G; deCODE genetics/Amgen, Inc, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Department of Internal Medicine, Division of Cardiology, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland., Esko T; Institute of Genomics, University of Tartu, Tartu, Estonia.; Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Trabetti E; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy., Tsao PS; VA Palo Alto Health Care System, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA., Tuomi T; Folkhälsan Research Centre, Helsinki, Finland.; Department of Endocrinology, Helsinki University Central Hospital, Helsinki, Finland.; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden Institute for Molecular Medicine Helsinki (FIMM), Helsinki University, Helsinki, Finland., Turner ST; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA., Tzoulaki I; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Vaartjes I; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, University of Utrecht, University of Utrecht, Utrecht, the Netherlands.; Center for Circulatory Health, University Medical Center Utrecht, University of Utrecht, Utrecht, the Netherlands., Vergnaud AC; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Willer CJ; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Wilson PWF; Atlanta VAMC and Emory Clinical Cardiovascular Research Institute, Atlanta, GA, USA., Witte DR; Department of Public Health, Aarhus University, Aarhus, Denmark.; Danish Diabetes Academy, Odense, Denmark.; Steno Diabetes Center Aarhus, Aarhus, Denmark., Yonova-Doing E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Zhang H; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA., Aliya N; International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh., Almgren P; Department of Medicine, Lund University, Malmö, Sweden., Amouyel P; Univ Lille, U1167 - RID-AGE - Facteurs de Risque et Déterminants Moléculaires des Maladies Liées au Vieillissement, Lille, France.; INSERM, U1167, Lille, France.; CHU Lille, U1167, Lille, France.; Institut Pasteur de Lille, U1167, Lille, France., Asselbergs FW; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.; Health Data Research UK, Institute of Health Informatics, University College London, London, UK., Barnes MR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Blakemore AI; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK.; Section of Investigative Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, UK., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Bots ML; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, University of Utrecht, University of Utrecht, Utrecht, the Netherlands.; Center for Circulatory Health, University Medical Center Utrecht, University of Utrecht, Utrecht, the Netherlands., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Buring JE; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Chambers JC; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Imperial College Healthcare NHS Trust, London, UK., Chen YI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Chowdhury R; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Non-communicable Disease Research (CNCR), Dhaka, Bangladesh., Conen D; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.; Cardiovascular Research Institute Basel, Basel, Switzerland., Correa A; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Davey Smith G; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Boer RA; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK.; Centre for Genomic Health, Life Sciences, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Di Angelantonio E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK.; National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK., Elliott P; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Health Data Research UK-London at Imperial College London, London, UK.; UKDRI, Dementia Research Institute at Imperial College London, London, UK.; British Heart Foundation (BHF) Centre of Research Excellence, Imperial College London, London, UK., Felix SB; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Ferrières J; Department of Cardiology and Department of Epidemiology, INSERM UMR 1027, Toulouse University Hospital, Toulouse, France., Ford I; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK., Fornage M; Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden.; Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.; Department of Public Health & Clinical Medicine, Umeå University, Umeå, Sweden.; Oxford Center for Diabetes, Endocrinology & Metabolism, Radcliff Department of Medicine, University of Oxford, Oxford, UK., Franks S; Institute of Reproductive & Developmental Biology, Imperial College London, London, UK., Frossard P; Centre for Non-Communicable Diseases, Karachi, Pakistan., Gambaro G; Division of Nephrology, Department of Medicine, University of Verona, Verona, Italy., Gaunt TR; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Groop L; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden.; Institute for Molecular Medicine Helsinki (FIMM), Helsinki University, Helsinki, Finland., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute of Aging, Bethesda, MD, USA., Hayward C; MRC Human Genetics Unit, IGMM, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Hennig BJ; MRC Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, Gambia.; Wellcome Trust, London, UK., Herzig KH; Institute of Biomedicine, Medical Research Center (MRC), University of Oulu, and University Hospital Oulu, Oulu, Finland.; Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, Poznan, Poland., Ingelsson E; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA., Tuomilehto J; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Saudi Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.; National Institute of Public Health, Madrid, Spain., Järvelin MR; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK.; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Unit of Primary Care, Oulu University Hospital, Kajaanintie, Oulu, Finland.; Center for Life-Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Netherlands Heart Institute, Utrecht, the Netherlands., Kardia SLR; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Kee F; Centre for Public Health, Queens University Belfast, Belfast, UK., Kooner JS; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; National Heart and Lung Institute, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK., Kooperberg C; Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, WA, USA., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute of Aging, Bethesda, MD, USA., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Loos RJF; The Charles Bronfman Institute for Personalized Medicine at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Majumder AAS; National Institute of Cardiovascular Diseases, Sher-e-Bangla Nagar, Dhaka, Bangladesh., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., McCarthy MI; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK.; Genentech, South San Francisco, San Francisco, CA, USA., Melander O; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Murray AD; The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK., Nordestgaard BG; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Orho-Melander M; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Packard CJ; University of Glasgow, Glasgow, UK., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK., Palmas W; Department of Medicine, Columbia University Medical Center, New York, NY, USA., Polasek O; Department of Public Health, University of Split School of Medicine, Split, Croatia., Porteous DJ; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, UK., Prentice AM; MRC Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, Gambia.; MRC International Nutrition Group at London School of Hygiene and Tropical Medicine, Keppel St, London, UK., Province MA; Division of Statistical Genomics, Department of Genetics and Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA., Relton CL; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Rice K; Department of Biostatistics, University of Washington, Seattle, WA, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Rolandsson O; Department of Public Health & Clinical Medicine, Umeå University, Umeå, Sweden., Rosendaal FR; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Rotter JI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Scotland, UK., Salomaa V; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Centre, Leicester, UK., Sattar N; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, UK., Sheu WH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan.; Institute of Medical Technology, National Chung-Hsing University, Taichung, Taiwan., Smith BH; Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Soranzo N; National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK.; Department of Human Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Research Centre, University of Edinburgh, Edinburgh, UK., Sebert S; Center for Life-Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland., Taylor KD; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Lakka TA; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio, Finland., Timpson NJ; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Tobin MD; National Institute for Health Research Leicester Biomedical Research Centre, Leicester, UK.; Department of Health Sciences, University of Leicester, Leicester, UK., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands.; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, the Netherlands., van der Meer P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands., Ramachandran VS; Boston University and National Heart, Lung and Blood Institute Framingham Heart Study, Framingham, MA, USA.; Boston University Schools of Medicine and Public Health, Boston, MA, USA., Verweij N; University Medical Center Groningen, Groningen, the Netherlands., Virtamo J; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Völker U; Interfaculty Institute for Genetics and Functional Genomics, University Medicine and University of Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Zeggini E; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Institute of Translational Genomics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; TUM School of Medicine, Technical University of Munich and Klinikum Rechts der Isar, Munich, Germany., Charchar FJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; Health Innovation and Transformation Center, Federation University Australia, Ballarat, Victoria, Australia.; Department of Physiology, University of Melbourne, Melbourne, Victoria, Australia., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Tomaszewski M; Division of Cardiovascular Sciences, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK.; Division of Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK.; National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK., Caulfield MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Danesh J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK.; National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK.; Department of Human Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Edwards TL; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Holm H; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Hung AM; VA Tennessee Valley Healthcare System, Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt Center for Kidney Disease, Vanderbilt University Medical Center, Nashville, TN, USA., Lindgren CM; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; The Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Liu C; Boston University School of Public Health, Boston, MA, USA., Manning AK; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Clinical and Translational Epidemiology Unit, Mongan Institute, Massachusetts General Hospital, Boston, MA, USA., Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, University of Manchester, Manchester, UK., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., O'Donnell CJ; VA Boston Healthcare, Section of Cardiology and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Saleheen D; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Non-Communicable Diseases, Karachi, Pakistan., Stefansson K; deCODE genetics/Amgen, Inc, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Levy D; Boston University and National Heart, Lung and Blood Institute Framingham Heart Study, Framingham, MA, USA.; Population Sciences, Branch, National Heart, Lung, and Blood Institute, National Institute of Health, Bethesda, MD, USA., Newton-Cheh C; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Munroe PB; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. p.b.munroe@qmul.ac.uk.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK. p.b.munroe@qmul.ac.uk., Howson JMM; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. JMMHowson@gmail.com.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK. JMMHowson@gmail.com.; Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK. JMMHowson@gmail.com.; Novo Nordisk Research Centre Oxford, Novo Nordisk Ltd, Oxford, UK. JMMHowson@gmail.com.
Publikováno v:
Nature genetics [Nat Genet] 2020 Dec; Vol. 52 (12), pp. 1314-1332. Date of Electronic Publication: 2020 Nov 23.
Autor:
Bramham K; Department of Women and Children's Health, School of Life Course Sciences, King's College London , London, UK., Villa PM; Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital , Helsinki, Finland., Joslin JR; Department of Renal Sciences, School of Immunology and Microbial Sciences, King's College London , London, UK., Laivuori H; Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital , Helsinki, Finland.; Medical and Clinical Genetics, University of Helsinki and Helsinki University Hospital , Helsinki, Finland.; Institute for Molecular Medicine Finland, University of Helsinki , Helsinki, Finland., Hämäläinen E; Clinical Chemistry, University of Helsinki and Helsinki University Hospital , Helsinki, Finland., Kajantie E; Department of Health, National Institute for Health and Welfare , Helsinki, Finland.; Children's Hospital, University of Helsinki and Helsinki University Hospital , Helsinki, Finland., Räikkönen K; Institute of Behavioral Sciences, University Of Helsinki , Helsinki, Finland., Pesonen A; Institute of Behavioral Sciences, University Of Helsinki , Helsinki, Finland., Seed P; Department of Women and Children's Health, School of Life Course Sciences, King's College London , London, UK., Dalton RN; WellChild Laboratory, King's College London and King's Health Partners , London, UK., Turner C; WellChild Laboratory, King's College London and King's Health Partners , London, UK., Wong M; WellChild Laboratory, King's College London and King's Health Partners , London, UK., Von Dadelszen P; Department of Women and Children's Health, School of Life Course Sciences, King's College London , London, UK., Roberts JM; Magee-Womens Research Institute, University of Pittsburgh , Philadelphia, PA, USA., Poston L; Department of Women and Children's Health, School of Life Course Sciences, King's College London , London, UK., Chappell LC; Department of Women and Children's Health, School of Life Course Sciences, King's College London , London, UK.
Publikováno v:
Hypertension in pregnancy [Hypertens Pregnancy] 2020 Aug; Vol. 39 (3), pp. 326-335. Date of Electronic Publication: 2020 Jun 01.
Autor:
Lahti-Pulkkinen M; From the Faculty of Medicine, Department of Psychology and Logopedics, University of Helsinki, Finland (M.L.-P., P.G., S.T., S.S., J. Lahti, K.H., J. Lipsanen, H.L., K.R.).; National Institute for Health and Welfare, Helsinki, Finland (M.L.-P., S.S., E.K.).; University of Edinburgh, United Kingdom (M.L.-P., R.M.R.)., Girchenko P; From the Faculty of Medicine, Department of Psychology and Logopedics, University of Helsinki, Finland (M.L.-P., P.G., S.T., S.S., J. Lahti, K.H., J. Lipsanen, H.L., K.R.)., Tuovinen S; From the Faculty of Medicine, Department of Psychology and Logopedics, University of Helsinki, Finland (M.L.-P., P.G., S.T., S.S., J. Lahti, K.H., J. Lipsanen, H.L., K.R.)., Sammallahti S; From the Faculty of Medicine, Department of Psychology and Logopedics, University of Helsinki, Finland (M.L.-P., P.G., S.T., S.S., J. Lahti, K.H., J. Lipsanen, H.L., K.R.).; National Institute for Health and Welfare, Helsinki, Finland (M.L.-P., S.S., E.K.).; Erasmus Medical Center, Rotterdam, the Netherlands (S.S.)., Reynolds RM; University of Edinburgh, United Kingdom (M.L.-P., R.M.R.)., Lahti J; From the Faculty of Medicine, Department of Psychology and Logopedics, University of Helsinki, Finland (M.L.-P., P.G., S.T., S.S., J. Lahti, K.H., J. Lipsanen, H.L., K.R.).; University of Turku, Finland (J. Lahti)., Heinonen K; From the Faculty of Medicine, Department of Psychology and Logopedics, University of Helsinki, Finland (M.L.-P., P.G., S.T., S.S., J. Lahti, K.H., J. Lipsanen, H.L., K.R.)., Lipsanen J; From the Faculty of Medicine, Department of Psychology and Logopedics, University of Helsinki, Finland (M.L.-P., P.G., S.T., S.S., J. Lahti, K.H., J. Lipsanen, H.L., K.R.)., Hämäläinen E; University of Helsinki and Helsinki University Hospital, Finland (E.H., P.M.V., E.K., H.L.)., Villa PM; University of Helsinki and Helsinki University Hospital, Finland (E.H., P.M.V., E.K., H.L.).; Hyvinkää Hospital, Finland (P.M.V.)., Kajantie E; National Institute for Health and Welfare, Helsinki, Finland (M.L.-P., S.S., E.K.).; University of Helsinki and Helsinki University Hospital, Finland (E.H., P.M.V., E.K., H.L.).; Oulu University Hospital and University of Oulu, Finland (E.K.).; Norwegian University for Science and Technology, Trondheim, Norway (E.K.)., Laivuori H; From the Faculty of Medicine, Department of Psychology and Logopedics, University of Helsinki, Finland (M.L.-P., P.G., S.T., S.S., J. Lahti, K.H., J. Lipsanen, H.L., K.R.).; University of Helsinki and Helsinki University Hospital, Finland (E.H., P.M.V., E.K., H.L.).; University of Tampere, Finland (H.L.)., Räikkönen K; From the Faculty of Medicine, Department of Psychology and Logopedics, University of Helsinki, Finland (M.L.-P., P.G., S.T., S.S., J. Lahti, K.H., J. Lipsanen, H.L., K.R.).
Publikováno v:
Hypertension (Dallas, Tex. : 1979) [Hypertension] 2020 Jun; Vol. 75 (6), pp. 1429-1438. Date of Electronic Publication: 2020 Apr 20.
Autor:
Lokki AI; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.). inkeri.lokki@helsinki.fi hannele.laivuori@helsinki.fi., Daly E; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.)., Triebwasser M; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.)., Kurki MI; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.)., Roberson EDO; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.)., Häppölä P; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.)., Auro K; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.)., Perola M; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.)., Heinonen S; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.)., Kajantie E; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.)., Kere J; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.)., Kivinen K; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.)., Pouta A; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.)., Salmon JE; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.)., Meri S; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.)., Daly M; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.)., Atkinson JP; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.)., Laivuori H; From the Immunobiology, Research Programs Unit (A.I.L., S.M.), Molecular Neurology, Research Programs Unit (J.K.), and Institute for Molecular Medicine Finland/HiLIFE Unit (P.H., K.A., M.P., H.L.), University of Helsinki, Finland; Medical and Clinical Genetics (A.I.L., H.L.), Bacteriology and Immunology (A.I.L., S.M.), Obstetrics and Gynaecology (K.A., S.H., H.L.), and Children's Hospital (E.K), University of Helsinki and Helsinki University Hospital, Finland; Folkhälsan Institute of Genetics (J.K.), University of Helsinki, Finland; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA (E.D., M.I.K., M.D.); Department of Medicine, Division of Rheumatology (M.T., E.D.O.R., J.P.A.) and Department of Genetics (E.D.O.R.), Washington University School of Medicine, St. Louis, MO; Neurosurgery of Neuro Center, Kuopio University Hospital, Finland (M.I.K.); Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston (M.I.K.); Unit of Genetics and Biomarkers (K.A.), Department of Health (M.P., E.K.), Chronic Disease Prevention Unit, Department of Health (E.K.), and Department of Government Services (A.P.), National Institute for Health and Welfare, Helsinki, Finland; The Estonian Genome Center, University of Tartu, Estonia (M.P.); PEDEGO Research Unit, MRC Oulu, University of Oulu and Oulu University Hospital, Finland (E.K., A.P.); Department of Biosciences and Nutrition, Karolinska Institutet, Solna, Sweden (J.K.); Department of Medical and Molecular Genetics, King's College, London, United Kingdom (J.K.); Division of Cardiovascular Medicine, University of Cambridge, United Kingdom (K.K.); Department of Medicine, Hospital for Special Surgery-Weill Cornell Medicine, New York, NY (J.E.S.); and Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston (M.D.). inkeri.lokki@helsinki.fi hannele.laivuori@helsinki.fi.
Publikováno v:
Hypertension (Dallas, Tex. : 1979) [Hypertension] 2017 Aug; Vol. 70 (2), pp. 365-371. Date of Electronic Publication: 2017 Jun 26.
Autor:
Hovi P; From the Chronic Disease Prevention Unit, Department of Health, National Institute for Health and Welfare, Helsinki, Finland (P.H., E.K.); Department of Pediatrics, Helsinki University Central Hospital and University of Helsinki, Finland (P.H., S.A., E.K.); Department of Pediatrics, Women and Infants Hospital, Providence, RI (B.V., L.R.M.); Royal Women's Hospital, Melbourne, Australia (L.W.D.); Department of Obstetrics and Gynaecology, The University of Melbourne, Australia (L.W.D.); Department of Clinical Sciences, Murdoch Childrens Research Institute, Melbourne, Australia (L.W.D.); Respiratory Medicine Centre for Infection and Immunity, The Queen's University of Belfast, Northern Ireland (L.M.); Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada (K.M.M., S.S.); Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim (K.A.I.E., A.-M.B.); Department of Child Health, TNO, Leiden, The Netherlands (S.v.d.P.); Department of Pediatrics, University of British Columbia, Vancouver, Canada (R.E.G.); and PEDEGO Research Unit, MRC Oulu, Oulu University Hospital, University of Oulu, Finland (E.K.). petteri.hovi@helsinki.fi., Vohr B; From the Chronic Disease Prevention Unit, Department of Health, National Institute for Health and Welfare, Helsinki, Finland (P.H., E.K.); Department of Pediatrics, Helsinki University Central Hospital and University of Helsinki, Finland (P.H., S.A., E.K.); Department of Pediatrics, Women and Infants Hospital, Providence, RI (B.V., L.R.M.); Royal Women's Hospital, Melbourne, Australia (L.W.D.); Department of Obstetrics and Gynaecology, The University of Melbourne, Australia (L.W.D.); Department of Clinical Sciences, Murdoch Childrens Research Institute, Melbourne, Australia (L.W.D.); Respiratory Medicine Centre for Infection and Immunity, The Queen's University of Belfast, Northern Ireland (L.M.); Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada (K.M.M., S.S.); Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim (K.A.I.E., A.-M.B.); Department of Child Health, TNO, Leiden, The Netherlands (S.v.d.P.); Department of Pediatrics, University of British Columbia, Vancouver, Canada (R.E.G.); and PEDEGO Research Unit, MRC Oulu, Oulu University Hospital, University of Oulu, Finland (E.K.)., Ment LR; From the Chronic Disease Prevention Unit, Department of Health, National Institute for Health and Welfare, Helsinki, Finland (P.H., E.K.); Department of Pediatrics, Helsinki University Central Hospital and University of Helsinki, Finland (P.H., S.A., E.K.); Department of Pediatrics, Women and Infants Hospital, Providence, RI (B.V., L.R.M.); Royal Women's Hospital, Melbourne, Australia (L.W.D.); Department of Obstetrics and Gynaecology, The University of Melbourne, Australia (L.W.D.); Department of Clinical Sciences, Murdoch Childrens Research Institute, Melbourne, Australia (L.W.D.); Respiratory Medicine Centre for Infection and Immunity, The Queen's University of Belfast, Northern Ireland (L.M.); Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada (K.M.M., S.S.); Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim (K.A.I.E., A.-M.B.); Department of Child Health, TNO, Leiden, The Netherlands (S.v.d.P.); Department of Pediatrics, University of British Columbia, Vancouver, Canada (R.E.G.); and PEDEGO Research Unit, MRC Oulu, Oulu University Hospital, University of Oulu, Finland (E.K.)., Doyle LW; From the Chronic Disease Prevention Unit, Department of Health, National Institute for Health and Welfare, Helsinki, Finland (P.H., E.K.); Department of Pediatrics, Helsinki University Central Hospital and University of Helsinki, Finland (P.H., S.A., E.K.); Department of Pediatrics, Women and Infants Hospital, Providence, RI (B.V., L.R.M.); Royal Women's Hospital, Melbourne, Australia (L.W.D.); Department of Obstetrics and Gynaecology, The University of Melbourne, Australia (L.W.D.); Department of Clinical Sciences, Murdoch Childrens Research Institute, Melbourne, Australia (L.W.D.); Respiratory Medicine Centre for Infection and Immunity, The Queen's University of Belfast, Northern Ireland (L.M.); Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada (K.M.M., S.S.); Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim (K.A.I.E., A.-M.B.); Department of Child Health, TNO, Leiden, The Netherlands (S.v.d.P.); Department of Pediatrics, University of British Columbia, Vancouver, Canada (R.E.G.); and PEDEGO Research Unit, MRC Oulu, Oulu University Hospital, University of Oulu, Finland (E.K.)., McGarvey L; From the Chronic Disease Prevention Unit, Department of Health, National Institute for Health and Welfare, Helsinki, Finland (P.H., E.K.); Department of Pediatrics, Helsinki University Central Hospital and University of Helsinki, Finland (P.H., S.A., E.K.); Department of Pediatrics, Women and Infants Hospital, Providence, RI (B.V., L.R.M.); Royal Women's Hospital, Melbourne, Australia (L.W.D.); Department of Obstetrics and Gynaecology, The University of Melbourne, Australia (L.W.D.); Department of Clinical Sciences, Murdoch Childrens Research Institute, Melbourne, Australia (L.W.D.); Respiratory Medicine Centre for Infection and Immunity, The Queen's University of Belfast, Northern Ireland (L.M.); Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada (K.M.M., S.S.); Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim (K.A.I.E., A.-M.B.); Department of Child Health, TNO, Leiden, The Netherlands (S.v.d.P.); Department of Pediatrics, University of British Columbia, Vancouver, Canada (R.E.G.); and PEDEGO Research Unit, MRC Oulu, Oulu University Hospital, University of Oulu, Finland (E.K.)., Morrison KM; From the Chronic Disease Prevention Unit, Department of Health, National Institute for Health and Welfare, Helsinki, Finland (P.H., E.K.); Department of Pediatrics, Helsinki University Central Hospital and University of Helsinki, Finland (P.H., S.A., E.K.); Department of Pediatrics, Women and Infants Hospital, Providence, RI (B.V., L.R.M.); Royal Women's Hospital, Melbourne, Australia (L.W.D.); Department of Obstetrics and Gynaecology, The University of Melbourne, Australia (L.W.D.); Department of Clinical Sciences, Murdoch Childrens Research Institute, Melbourne, Australia (L.W.D.); Respiratory Medicine Centre for Infection and Immunity, The Queen's University of Belfast, Northern Ireland (L.M.); Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada (K.M.M., S.S.); Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim (K.A.I.E., A.-M.B.); Department of Child Health, TNO, Leiden, The Netherlands (S.v.d.P.); Department of Pediatrics, University of British Columbia, Vancouver, Canada (R.E.G.); and PEDEGO Research Unit, MRC Oulu, Oulu University Hospital, University of Oulu, Finland (E.K.)., Evensen KA; From the Chronic Disease Prevention Unit, Department of Health, National Institute for Health and Welfare, Helsinki, Finland (P.H., E.K.); Department of Pediatrics, Helsinki University Central Hospital and University of Helsinki, Finland (P.H., S.A., E.K.); Department of Pediatrics, Women and Infants Hospital, Providence, RI (B.V., L.R.M.); Royal Women's Hospital, Melbourne, Australia (L.W.D.); Department of Obstetrics and Gynaecology, The University of Melbourne, Australia (L.W.D.); Department of Clinical Sciences, Murdoch Childrens Research Institute, Melbourne, Australia (L.W.D.); Respiratory Medicine Centre for Infection and Immunity, The Queen's University of Belfast, Northern Ireland (L.M.); Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada (K.M.M., S.S.); Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim (K.A.I.E., A.-M.B.); Department of Child Health, TNO, Leiden, The Netherlands (S.v.d.P.); Department of Pediatrics, University of British Columbia, Vancouver, Canada (R.E.G.); and PEDEGO Research Unit, MRC Oulu, Oulu University Hospital, University of Oulu, Finland (E.K.)., van der Pal S; From the Chronic Disease Prevention Unit, Department of Health, National Institute for Health and Welfare, Helsinki, Finland (P.H., E.K.); Department of Pediatrics, Helsinki University Central Hospital and University of Helsinki, Finland (P.H., S.A., E.K.); Department of Pediatrics, Women and Infants Hospital, Providence, RI (B.V., L.R.M.); Royal Women's Hospital, Melbourne, Australia (L.W.D.); Department of Obstetrics and Gynaecology, The University of Melbourne, Australia (L.W.D.); Department of Clinical Sciences, Murdoch Childrens Research Institute, Melbourne, Australia (L.W.D.); Respiratory Medicine Centre for Infection and Immunity, The Queen's University of Belfast, Northern Ireland (L.M.); Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada (K.M.M., S.S.); Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim (K.A.I.E., A.-M.B.); Department of Child Health, TNO, Leiden, The Netherlands (S.v.d.P.); Department of Pediatrics, University of British Columbia, Vancouver, Canada (R.E.G.); and PEDEGO Research Unit, MRC Oulu, Oulu University Hospital, University of Oulu, Finland (E.K.)., Grunau RE; From the Chronic Disease Prevention Unit, Department of Health, National Institute for Health and Welfare, Helsinki, Finland (P.H., E.K.); Department of Pediatrics, Helsinki University Central Hospital and University of Helsinki, Finland (P.H., S.A., E.K.); Department of Pediatrics, Women and Infants Hospital, Providence, RI (B.V., L.R.M.); Royal Women's Hospital, Melbourne, Australia (L.W.D.); Department of Obstetrics and Gynaecology, The University of Melbourne, Australia (L.W.D.); Department of Clinical Sciences, Murdoch Childrens Research Institute, Melbourne, Australia (L.W.D.); Respiratory Medicine Centre for Infection and Immunity, The Queen's University of Belfast, Northern Ireland (L.M.); Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada (K.M.M., S.S.); Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim (K.A.I.E., A.-M.B.); Department of Child Health, TNO, Leiden, The Netherlands (S.v.d.P.); Department of Pediatrics, University of British Columbia, Vancouver, Canada (R.E.G.); and PEDEGO Research Unit, MRC Oulu, Oulu University Hospital, University of Oulu, Finland (E.K.)., Brubakk AM; From the Chronic Disease Prevention Unit, Department of Health, National Institute for Health and Welfare, Helsinki, Finland (P.H., E.K.); Department of Pediatrics, Helsinki University Central Hospital and University of Helsinki, Finland (P.H., S.A., E.K.); Department of Pediatrics, Women and Infants Hospital, Providence, RI (B.V., L.R.M.); Royal Women's Hospital, Melbourne, Australia (L.W.D.); Department of Obstetrics and Gynaecology, The University of Melbourne, Australia (L.W.D.); Department of Clinical Sciences, Murdoch Childrens Research Institute, Melbourne, Australia (L.W.D.); Respiratory Medicine Centre for Infection and Immunity, The Queen's University of Belfast, Northern Ireland (L.M.); Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada (K.M.M., S.S.); Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim (K.A.I.E., A.-M.B.); Department of Child Health, TNO, Leiden, The Netherlands (S.v.d.P.); Department of Pediatrics, University of British Columbia, Vancouver, Canada (R.E.G.); and PEDEGO Research Unit, MRC Oulu, Oulu University Hospital, University of Oulu, Finland (E.K.)., Andersson S; From the Chronic Disease Prevention Unit, Department of Health, National Institute for Health and Welfare, Helsinki, Finland (P.H., E.K.); Department of Pediatrics, Helsinki University Central Hospital and University of Helsinki, Finland (P.H., S.A., E.K.); Department of Pediatrics, Women and Infants Hospital, Providence, RI (B.V., L.R.M.); Royal Women's Hospital, Melbourne, Australia (L.W.D.); Department of Obstetrics and Gynaecology, The University of Melbourne, Australia (L.W.D.); Department of Clinical Sciences, Murdoch Childrens Research Institute, Melbourne, Australia (L.W.D.); Respiratory Medicine Centre for Infection and Immunity, The Queen's University of Belfast, Northern Ireland (L.M.); Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada (K.M.M., S.S.); Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim (K.A.I.E., A.-M.B.); Department of Child Health, TNO, Leiden, The Netherlands (S.v.d.P.); Department of Pediatrics, University of British Columbia, Vancouver, Canada (R.E.G.); and PEDEGO Research Unit, MRC Oulu, Oulu University Hospital, University of Oulu, Finland (E.K.)., Saigal S; From the Chronic Disease Prevention Unit, Department of Health, National Institute for Health and Welfare, Helsinki, Finland (P.H., E.K.); Department of Pediatrics, Helsinki University Central Hospital and University of Helsinki, Finland (P.H., S.A., E.K.); Department of Pediatrics, Women and Infants Hospital, Providence, RI (B.V., L.R.M.); Royal Women's Hospital, Melbourne, Australia (L.W.D.); Department of Obstetrics and Gynaecology, The University of Melbourne, Australia (L.W.D.); Department of Clinical Sciences, Murdoch Childrens Research Institute, Melbourne, Australia (L.W.D.); Respiratory Medicine Centre for Infection and Immunity, The Queen's University of Belfast, Northern Ireland (L.M.); Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada (K.M.M., S.S.); Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim (K.A.I.E., A.-M.B.); Department of Child Health, TNO, Leiden, The Netherlands (S.v.d.P.); Department of Pediatrics, University of British Columbia, Vancouver, Canada (R.E.G.); and PEDEGO Research Unit, MRC Oulu, Oulu University Hospital, University of Oulu, Finland (E.K.)., Kajantie E; From the Chronic Disease Prevention Unit, Department of Health, National Institute for Health and Welfare, Helsinki, Finland (P.H., E.K.); Department of Pediatrics, Helsinki University Central Hospital and University of Helsinki, Finland (P.H., S.A., E.K.); Department of Pediatrics, Women and Infants Hospital, Providence, RI (B.V., L.R.M.); Royal Women's Hospital, Melbourne, Australia (L.W.D.); Department of Obstetrics and Gynaecology, The University of Melbourne, Australia (L.W.D.); Department of Clinical Sciences, Murdoch Childrens Research Institute, Melbourne, Australia (L.W.D.); Respiratory Medicine Centre for Infection and Immunity, The Queen's University of Belfast, Northern Ireland (L.M.); Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada (K.M.M., S.S.); Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim (K.A.I.E., A.-M.B.); Department of Child Health, TNO, Leiden, The Netherlands (S.v.d.P.); Department of Pediatrics, University of British Columbia, Vancouver, Canada (R.E.G.); and PEDEGO Research Unit, MRC Oulu, Oulu University Hospital, University of Oulu, Finland (E.K.).
Publikováno v:
Hypertension (Dallas, Tex. : 1979) [Hypertension] 2016 Oct; Vol. 68 (4), pp. 880-7. Date of Electronic Publication: 2016 Aug 29.
Autor:
Surendran P; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Drenos F; Medical Research Council Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, UK.; Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, Rayne Building University College London, London, UK., Young R; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Warren H; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, UK., Cook JP; Department of Health Sciences, University of Leicester, Leicester, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Manning AK; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts, USA.; Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA., Grarup N; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sim X; Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA.; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.; Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore., Barnes DR; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Witkowska K; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, UK., Staley JR; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Tragante V; Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands., Tukiainen T; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA., Yaghootkar H; Genetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK., Masca N; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Unit in Cardiovascular Disease, Leicester, UK., Freitag DF; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Ferreira T; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Giannakopoulou O; Heart Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Tinker A; Heart Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, UK., Harakalova M; Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Liu C; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, USA., Kraja AT; Division of Statistical Genomics, Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Fallgaard Nielsen S; Department of Clinical Biochemistry Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark., Rasheed A; Centre for Non-Communicable Diseases, Karachi, Pakistan., Samuel M; Centre for Non-Communicable Diseases, Karachi, Pakistan., Zhao W; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Bonnycastle LL; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Jackson AU; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA., Narisu N; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Swift AJ; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Southam L; Wellcome Trust Sanger Institute, Genome Campus, Hinxton, UK.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Marten J; Medical Research Council Human Genetics Unit, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Huyghe JR; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA., Stančáková A; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Fava C; University of Lund, Department of Clinical Sciences, Malmö, Sweden.; University of Verona, Department of Medicine, Verona, Italy., Ohlsson T; University of Lund, Department of Clinical Sciences, Malmö, Sweden., Matchan A; Wellcome Trust Sanger Institute, Genome Campus, Hinxton, UK., Stirrups KE; Heart Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Bork-Jensen J; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Gjesing AP; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kontto J; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Perola M; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Institute of Molecular Medicine FIMM, University of Helsinki, Finland.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Shaw-Hawkins S; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, UK., Havulinna AS; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Zhang H; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA., Donnelly LA; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Groves CJ; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Rayner NW; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Trust Sanger Institute, Genome Campus, Hinxton, UK., Neville MJ; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospital Trusts, Oxford, UK., Robertson NR; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Yiorkas AM; Section of Investigative Medicine, Imperial College London, London, UK.; Department of Life Sciences, Brunel University London, London, UK., Herzig KH; Institute of Biomedicine, Biocenter Oulu, University of Oulu, Oulu, Finland.; Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, Poznan, Poland., Kajantie E; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Hospital for Children and Adolescents, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland.; Department of Obstetrics and Gynaecology, Oulu University Hospital and University of Oulu, Oulu, Finland., Zhang W; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK., Willems SM; Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Lannfelt L; Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., Malerba G; Section of Biology and Genetics, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy., Soranzo N; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; The National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK., Trabetti E; Section of Biology and Genetics, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy., Verweij N; University Medical Center Groningen, University of Groningen, Department of Cardiology, The Netherlands.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA., Evangelou E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Moayyeri A; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Farr Institute of Health Informatics Research, Institute of Health Informatics, University College London, London, UK., Vergnaud AC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Unit in Cardiovascular Disease, Leicester, UK., Poveda A; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden.; Department of Genetics, Physical Anthropology and Animal Physiology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Bilbao, Spain., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden., Caslake M; University of Glasgow, Glasgow, UK., de Craen AJ; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.; Mr. De Craen suddenly passed away January 2016., Trompet S; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands., Luan J; Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Scott RA; Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Genomic and Experimental Medicine, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Liewald DC; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Marioni R; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Genomic and Experimental Medicine, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, UK., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Hallmans G; Department of Biobank Research, Umeå University, Umeå, Sweden., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden.; Department of Biobank Research, Umeå University, Umeå, Sweden., Huffman JE; Medical Research Council Human Genetics Unit, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, USA., Hassinen M; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Burgess S; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Vasan RS; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, USA.; Section of Cardiology, Department of Medicine, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, USA.; Sections of Preventive Medicine and Epidemiology, Department of Medicine, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, USA., Felix JF; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Uria-Nickelsen M; Development Management and Planning, Pfizer Worldwide Research and Development., Malarstig A; Pfizer Worldwide Research and Development, Stockholm, Sweden., Reily DF; Merck Research Laboratories, Genetics and Pharmacogenomics, Boston, Massachusetts, USA., Hoek M; Merck Research Laboratories, Cardiometabolic Disease, Kenilworth, New Jersey, USA., Vogt T; Merck Research Laboratories, Cardiometabolic Disease, Kenilworth, New Jersey, USA.; CHDI Management/CHDI Foundation, Princeton, New Jersey, USA., Lin H; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, USA.; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA., Lieb W; Institute of Epidemiology and Biobank Popgen, Kiel University, Kiel, Germany., Traylor M; Neurology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Markus HF; Neurology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Highland HM; University of North Carolina at Chapel Hill, Department of Epidemiology, Chapel Hill, North Carolina, USA., Justice AE; University of North Carolina at Chapel Hill, Department of Epidemiology, Chapel Hill, North Carolina, USA., Marouli E; Heart Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Lindström J; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Uusitupa M; Department of Public Health and Clinical Nutrition, University of Eastern Finland, Finland.; Research Unit, Kuopio University Hospital, Kuopio, Finland., Komulainen P; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Lakka TA; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Polasek O; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; Faculty of Medicine, University of Split, Croatia., Rudan I; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Rolandsson O; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden.; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, UK., Jousilahti P; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Männistö S; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Research Centre, University of Edinburgh, Edinburgh, UK., Langenberg C; Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Wareham NJ; Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Brown MJ; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, UK., Dominiczak AF; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Connell JM; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; The Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands., Sattar N; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Ford I; University of Glasgow, Glasgow, UK., Packard CJ; University of Glasgow, Glasgow, UK., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts, USA., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, Tartu, Estonia., de Boer RA; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., van der Meer P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands., Gambaro G; Division of Nephrology, Department of Internal Medicine and Medical Specialties, Columbus - Gemelli University Hospital, Catholic University, Rome, Italy., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, USA., Lind L; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., de Bakker PI; Department of Medical Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands., Numans ME; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands., Brandslund I; Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Christensen C; Medical Department, Lillebaelt Hospital, Vejle, Denmark., Petersen ER; Department of Clinical Immunology and Biochemistry, Lillebaelt Hospital, Vejle, Denmark., Korpi-Hyövälti E; South Ostrobothnia Central Hospital, Seinäjoki, Finland., Oksa H; Tampere University Hospital, Tampere, Finland., Chambers JC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK., Kooner JS; Department of Cardiology, Ealing Hospital, Middlesex, UK.; National Heart and Lung Institute, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK., Blakemore AI; Section of Investigative Medicine, Imperial College London, London, UK.; Department of Life Sciences, Brunel University London, London, UK., Franks S; Institute of Reproductive and Developmental Biology, Imperial College London, London, UK., Jarvelin MR; Department of Epidemiology and Biostatistics, Medical Research Council Public Health England Centre for Environment and Health, School of Public Health, Faculty of Medicine, Imperial College London, St. Mary's Campus, London, UK.; Centre for Life Course Epidemiology, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., Husemoen LL; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark., Linneberg A; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark.; Department of Clinical Experimental Research, Glostrup University Hospital, Glostrup, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Skaaby T; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark., Thuesen B; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark., Karpe F; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospital Trusts, Oxford, UK., Tuomilehto J; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Dasman Diabetes Institute, Dasman, Kuwait.; Centre for Vascular Prevention, Danube-University Krems, Krems, Austria.; King Abdulaziz University, Jeddah, Saudi Arabia., Doney AS; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Morris AD; School of Molecular, Genetic and Population Health Sciences, University of Edinburgh, Medical School, Teviot Place, Edinburgh, UK., Palmer CN; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Holmen OL; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.; St. Olav Hospital, Trondheim University Hospital, Trondheim, Norway., Hveem K; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.; Department of Medicine, Levanger Hospital, Nord- Trøndelag Health Trust, Levanger, Norway., Willer CJ; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA., Tuomi T; Folkhälsan Research Centre, Helsinki, Finland; Department of Endocrinology, Helsinki University Central Hospital, Helsinki, Finland.; Institute for Molecular Medicine Finland University of Helsinki, Helsinki, Finland., Groop L; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden.; Institute for Molecular Medicine Finland University of Helsinki, Helsinki, Finland., Käräjämäki A; Department of Primary Health Care, Vaasa Central Hospital, Vaasa, Finland.; Diabetes Center, Vaasa Health Care Center, Vaasa, Finland., Palotie A; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts, USA.; Institute for Molecular Medicine Finland University of Helsinki, Helsinki, Finland.; Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA., Ripatti S; Institute for Molecular Medicine Finland University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Finland.; Wellcome Trust Sanger Institute, Genome Campus, Hinxton, UK., Salomaa V; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Alam DS; ICDDR, B; Mohakhali, Dhaka, Bangladesh., Shafi Majumder AA; National Institute of Cardiovascular Diseases, Sher-e-Bangla Nagar, Dhaka, Bangladesh., Di Angelantonio E; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; The National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK., Chowdhury R; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., McCarthy MI; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospital Trusts, Oxford, UK.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Poulter N; International Centre for Circulatory Health, Imperial College London, UK., Stanton AV; Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland., Sever P; International Centre for Circulatory Health, Imperial College London, UK., Amouyel P; University of Lille, UMR1167, Risk Factors and Molecular Determinants of aging-related diseases, Lille, France.; Inserm, Lille, France.; Centre Hospitalier Universitaire Lille, Public Health, Lille, France.; Institut Pasteur de Lille, Lille, France., Arveiler D; Department of Epidemiology and Public Health, EA 3430, University of Strasbourg, Strasbourg, France., Blankenberg S; Department of General and Interventional Cardiology, University Heart Center Hamburg, Germany.; University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Ferrières J; Department of Epidemiology, UMR 1027- INSERM, Toulouse University-CHU Toulouse, Toulouse, France., Kee F; Director, UKCRC Centre of Excellence for Public Health, Queens University, Belfast, Northern Ireland., Kuulasmaa K; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Veronesi G; Research Center in Epidemiology and Preventive Medicine, Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy., Virtamo J; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Deloukas P; Heart Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Elliott P; Department of Epidemiology and Biostatistics, Medical Research Council Public Health England Centre for Environment and Health, School of Public Health, Faculty of Medicine, Imperial College London, St. Mary's Campus, London, UK., Zeggini E; Wellcome Trust Sanger Institute, Genome Campus, Hinxton, UK., Kathiresan S; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts, USA., Melander O; University of Lund, Department of Clinical Sciences, Malmö, Sweden., Kuusisto J; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Porteous D; Centre for Genomic and Experimental Medicine, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Hayward C; Medical Research Council Human Genetics Unit, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Scotland G; A Collaboration between the University Medical Schools and NHS, Aberdeen, Dundee, Edinburgh and Glasgow, UK., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA., Hansen T; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Pedersen O; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Boehnke M; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA., Stringham HM; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA., Frossard P; Centre for Non-Communicable Diseases, Karachi, Pakistan., Newton-Cheh C; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, UK., Nordestgaard BG; Department of Clinical Biochemistry Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark., Caulfield MJ; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, UK., Mahajan A; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Morris AP; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Tomaszewski M; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Unit in Cardiovascular Disease, Leicester, UK.; Institute of Cardiovascular Sciences, University of Manchester, Manchester, UK., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Unit in Cardiovascular Disease, Leicester, UK., Saleheen D; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Centre for Non-Communicable Diseases, Karachi, Pakistan.; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Asselbergs FW; Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands.; Faculty of Population Health Sciences, Institute of Cardiovascular Science, University College London, London, UK., Lindgren CM; The Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts, USA.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Danesh J; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Wellcome Trust Sanger Institute, Hinxton, UK.; The National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK., Wain LV; Department of Health Sciences, University of Leicester, Leicester, UK., Butterworth AS; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; The National Institute for Health Research Blood and Transplant Research., Howson JM; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Munroe PB; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, UK.
Publikováno v:
Nature genetics [Nat Genet] 2016 Oct; Vol. 48 (10), pp. 1151-1161. Date of Electronic Publication: 2016 Sep 12.
Autor:
Sipola-Leppänen M, Vääräsmäki M, Tikanmäki M, Matinolli HM, Miettola S, Hovi P, Wehkalampi K, Ruokonen A, Sundvall J, Pouta A, Eriksson JG, Järvelin MR, Kajantie E
Publikováno v:
American journal of epidemiology [Am J Epidemiol] 2015 Jun 01; Vol. 181 (11), pp. 861-73. Date of Electronic Publication: 2015 May 05.
Autor:
Sipola-Leppänen M; From the Departments of Chronic Disease Prevention (M.S.-L., R.K., M.T., H.-M.M., P.H., J.G.E., E.K.) and Children and Families (M.-R.J., M.V.), National Institute for Health and Welfare, Oulu and Helsinki, Finland; Institute of Health Sciences (M.S.-L., M.T., M.-R.J.) and Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital (M.V., E.K.), University of Oulu, Oulu, Finland; Biocenter Oulu, Oulu, Finland (M.-R.J.); Department of Pediatrics and Adolescence, Oulu University Hospital, Oulu, Finland (M.S.-L.); Unit of Primary Care, Oulu, Finland (M.R.J.); Institute of Behavioural Sciences (S.M., A.-K.P., K.R.) and Children's Hospital, Helsinki University Central Hospital (P.H., E.K.), University of Helsinki, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland (J.G.E.); Department of Epidemiology and Biostatistics, Imperial College London, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, London, United Kingdom (M.-R.J.); and Folkhälsan Research Center, Helsinki, Finland (J.G.E.). marika.sipola-leppanen@thl.fi., Karvonen R; From the Departments of Chronic Disease Prevention (M.S.-L., R.K., M.T., H.-M.M., P.H., J.G.E., E.K.) and Children and Families (M.-R.J., M.V.), National Institute for Health and Welfare, Oulu and Helsinki, Finland; Institute of Health Sciences (M.S.-L., M.T., M.-R.J.) and Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital (M.V., E.K.), University of Oulu, Oulu, Finland; Biocenter Oulu, Oulu, Finland (M.-R.J.); Department of Pediatrics and Adolescence, Oulu University Hospital, Oulu, Finland (M.S.-L.); Unit of Primary Care, Oulu, Finland (M.R.J.); Institute of Behavioural Sciences (S.M., A.-K.P., K.R.) and Children's Hospital, Helsinki University Central Hospital (P.H., E.K.), University of Helsinki, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland (J.G.E.); Department of Epidemiology and Biostatistics, Imperial College London, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, London, United Kingdom (M.-R.J.); and Folkhälsan Research Center, Helsinki, Finland (J.G.E.)., Tikanmäki M; From the Departments of Chronic Disease Prevention (M.S.-L., R.K., M.T., H.-M.M., P.H., J.G.E., E.K.) and Children and Families (M.-R.J., M.V.), National Institute for Health and Welfare, Oulu and Helsinki, Finland; Institute of Health Sciences (M.S.-L., M.T., M.-R.J.) and Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital (M.V., E.K.), University of Oulu, Oulu, Finland; Biocenter Oulu, Oulu, Finland (M.-R.J.); Department of Pediatrics and Adolescence, Oulu University Hospital, Oulu, Finland (M.S.-L.); Unit of Primary Care, Oulu, Finland (M.R.J.); Institute of Behavioural Sciences (S.M., A.-K.P., K.R.) and Children's Hospital, Helsinki University Central Hospital (P.H., E.K.), University of Helsinki, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland (J.G.E.); Department of Epidemiology and Biostatistics, Imperial College London, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, London, United Kingdom (M.-R.J.); and Folkhälsan Research Center, Helsinki, Finland (J.G.E.)., Matinolli HM; From the Departments of Chronic Disease Prevention (M.S.-L., R.K., M.T., H.-M.M., P.H., J.G.E., E.K.) and Children and Families (M.-R.J., M.V.), National Institute for Health and Welfare, Oulu and Helsinki, Finland; Institute of Health Sciences (M.S.-L., M.T., M.-R.J.) and Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital (M.V., E.K.), University of Oulu, Oulu, Finland; Biocenter Oulu, Oulu, Finland (M.-R.J.); Department of Pediatrics and Adolescence, Oulu University Hospital, Oulu, Finland (M.S.-L.); Unit of Primary Care, Oulu, Finland (M.R.J.); Institute of Behavioural Sciences (S.M., A.-K.P., K.R.) and Children's Hospital, Helsinki University Central Hospital (P.H., E.K.), University of Helsinki, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland (J.G.E.); Department of Epidemiology and Biostatistics, Imperial College London, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, London, United Kingdom (M.-R.J.); and Folkhälsan Research Center, Helsinki, Finland (J.G.E.)., Martikainen S; From the Departments of Chronic Disease Prevention (M.S.-L., R.K., M.T., H.-M.M., P.H., J.G.E., E.K.) and Children and Families (M.-R.J., M.V.), National Institute for Health and Welfare, Oulu and Helsinki, Finland; Institute of Health Sciences (M.S.-L., M.T., M.-R.J.) and Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital (M.V., E.K.), University of Oulu, Oulu, Finland; Biocenter Oulu, Oulu, Finland (M.-R.J.); Department of Pediatrics and Adolescence, Oulu University Hospital, Oulu, Finland (M.S.-L.); Unit of Primary Care, Oulu, Finland (M.R.J.); Institute of Behavioural Sciences (S.M., A.-K.P., K.R.) and Children's Hospital, Helsinki University Central Hospital (P.H., E.K.), University of Helsinki, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland (J.G.E.); Department of Epidemiology and Biostatistics, Imperial College London, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, London, United Kingdom (M.-R.J.); and Folkhälsan Research Center, Helsinki, Finland (J.G.E.)., Pesonen AK; From the Departments of Chronic Disease Prevention (M.S.-L., R.K., M.T., H.-M.M., P.H., J.G.E., E.K.) and Children and Families (M.-R.J., M.V.), National Institute for Health and Welfare, Oulu and Helsinki, Finland; Institute of Health Sciences (M.S.-L., M.T., M.-R.J.) and Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital (M.V., E.K.), University of Oulu, Oulu, Finland; Biocenter Oulu, Oulu, Finland (M.-R.J.); Department of Pediatrics and Adolescence, Oulu University Hospital, Oulu, Finland (M.S.-L.); Unit of Primary Care, Oulu, Finland (M.R.J.); Institute of Behavioural Sciences (S.M., A.-K.P., K.R.) and Children's Hospital, Helsinki University Central Hospital (P.H., E.K.), University of Helsinki, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland (J.G.E.); Department of Epidemiology and Biostatistics, Imperial College London, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, London, United Kingdom (M.-R.J.); and Folkhälsan Research Center, Helsinki, Finland (J.G.E.)., Räikkönen K; From the Departments of Chronic Disease Prevention (M.S.-L., R.K., M.T., H.-M.M., P.H., J.G.E., E.K.) and Children and Families (M.-R.J., M.V.), National Institute for Health and Welfare, Oulu and Helsinki, Finland; Institute of Health Sciences (M.S.-L., M.T., M.-R.J.) and Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital (M.V., E.K.), University of Oulu, Oulu, Finland; Biocenter Oulu, Oulu, Finland (M.-R.J.); Department of Pediatrics and Adolescence, Oulu University Hospital, Oulu, Finland (M.S.-L.); Unit of Primary Care, Oulu, Finland (M.R.J.); Institute of Behavioural Sciences (S.M., A.-K.P., K.R.) and Children's Hospital, Helsinki University Central Hospital (P.H., E.K.), University of Helsinki, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland (J.G.E.); Department of Epidemiology and Biostatistics, Imperial College London, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, London, United Kingdom (M.-R.J.); and Folkhälsan Research Center, Helsinki, Finland (J.G.E.)., Järvelin MR; From the Departments of Chronic Disease Prevention (M.S.-L., R.K., M.T., H.-M.M., P.H., J.G.E., E.K.) and Children and Families (M.-R.J., M.V.), National Institute for Health and Welfare, Oulu and Helsinki, Finland; Institute of Health Sciences (M.S.-L., M.T., M.-R.J.) and Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital (M.V., E.K.), University of Oulu, Oulu, Finland; Biocenter Oulu, Oulu, Finland (M.-R.J.); Department of Pediatrics and Adolescence, Oulu University Hospital, Oulu, Finland (M.S.-L.); Unit of Primary Care, Oulu, Finland (M.R.J.); Institute of Behavioural Sciences (S.M., A.-K.P., K.R.) and Children's Hospital, Helsinki University Central Hospital (P.H., E.K.), University of Helsinki, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland (J.G.E.); Department of Epidemiology and Biostatistics, Imperial College London, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, London, United Kingdom (M.-R.J.); and Folkhälsan Research Center, Helsinki, Finland (J.G.E.)., Hovi P; From the Departments of Chronic Disease Prevention (M.S.-L., R.K., M.T., H.-M.M., P.H., J.G.E., E.K.) and Children and Families (M.-R.J., M.V.), National Institute for Health and Welfare, Oulu and Helsinki, Finland; Institute of Health Sciences (M.S.-L., M.T., M.-R.J.) and Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital (M.V., E.K.), University of Oulu, Oulu, Finland; Biocenter Oulu, Oulu, Finland (M.-R.J.); Department of Pediatrics and Adolescence, Oulu University Hospital, Oulu, Finland (M.S.-L.); Unit of Primary Care, Oulu, Finland (M.R.J.); Institute of Behavioural Sciences (S.M., A.-K.P., K.R.) and Children's Hospital, Helsinki University Central Hospital (P.H., E.K.), University of Helsinki, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland (J.G.E.); Department of Epidemiology and Biostatistics, Imperial College London, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, London, United Kingdom (M.-R.J.); and Folkhälsan Research Center, Helsinki, Finland (J.G.E.)., Eriksson JG; From the Departments of Chronic Disease Prevention (M.S.-L., R.K., M.T., H.-M.M., P.H., J.G.E., E.K.) and Children and Families (M.-R.J., M.V.), National Institute for Health and Welfare, Oulu and Helsinki, Finland; Institute of Health Sciences (M.S.-L., M.T., M.-R.J.) and Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital (M.V., E.K.), University of Oulu, Oulu, Finland; Biocenter Oulu, Oulu, Finland (M.-R.J.); Department of Pediatrics and Adolescence, Oulu University Hospital, Oulu, Finland (M.S.-L.); Unit of Primary Care, Oulu, Finland (M.R.J.); Institute of Behavioural Sciences (S.M., A.-K.P., K.R.) and Children's Hospital, Helsinki University Central Hospital (P.H., E.K.), University of Helsinki, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland (J.G.E.); Department of Epidemiology and Biostatistics, Imperial College London, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, London, United Kingdom (M.-R.J.); and Folkhälsan Research Center, Helsinki, Finland (J.G.E.)., Vääräsmäki M; From the Departments of Chronic Disease Prevention (M.S.-L., R.K., M.T., H.-M.M., P.H., J.G.E., E.K.) and Children and Families (M.-R.J., M.V.), National Institute for Health and Welfare, Oulu and Helsinki, Finland; Institute of Health Sciences (M.S.-L., M.T., M.-R.J.) and Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital (M.V., E.K.), University of Oulu, Oulu, Finland; Biocenter Oulu, Oulu, Finland (M.-R.J.); Department of Pediatrics and Adolescence, Oulu University Hospital, Oulu, Finland (M.S.-L.); Unit of Primary Care, Oulu, Finland (M.R.J.); Institute of Behavioural Sciences (S.M., A.-K.P., K.R.) and Children's Hospital, Helsinki University Central Hospital (P.H., E.K.), University of Helsinki, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland (J.G.E.); Department of Epidemiology and Biostatistics, Imperial College London, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, London, United Kingdom (M.-R.J.); and Folkhälsan Research Center, Helsinki, Finland (J.G.E.)., Kajantie E; From the Departments of Chronic Disease Prevention (M.S.-L., R.K., M.T., H.-M.M., P.H., J.G.E., E.K.) and Children and Families (M.-R.J., M.V.), National Institute for Health and Welfare, Oulu and Helsinki, Finland; Institute of Health Sciences (M.S.-L., M.T., M.-R.J.) and Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital (M.V., E.K.), University of Oulu, Oulu, Finland; Biocenter Oulu, Oulu, Finland (M.-R.J.); Department of Pediatrics and Adolescence, Oulu University Hospital, Oulu, Finland (M.S.-L.); Unit of Primary Care, Oulu, Finland (M.R.J.); Institute of Behavioural Sciences (S.M., A.-K.P., K.R.) and Children's Hospital, Helsinki University Central Hospital (P.H., E.K.), University of Helsinki, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland (J.G.E.); Department of Epidemiology and Biostatistics, Imperial College London, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, London, United Kingdom (M.-R.J.); and Folkhälsan Research Center, Helsinki, Finland (J.G.E.).
Publikováno v:
Hypertension (Dallas, Tex. : 1979) [Hypertension] 2015 Mar; Vol. 65 (3), pp. 615-21. Date of Electronic Publication: 2015 Jan 19.