Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Deary IJ"'
Autor:
Keaton JM; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Kamali Z; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Bioinformatics, Isfahan University of Medical Sciences, Isfahan, Iran., Xie T; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Vaez A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. a.vaez@umcg.nl.; Department of Bioinformatics, Isfahan University of Medical Sciences, Isfahan, Iran. a.vaez@umcg.nl., Williams A; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Goleva SB; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Ani A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Bioinformatics, Isfahan University of Medical Sciences, Isfahan, Iran., Evangelou E; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.; Department of Biomedical Research, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, Ioannina, Greece., Hellwege JN; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Biomedical Laboratory Research and Development, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Yengo L; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Young WJ; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK., Traylor M; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK., Giri A; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Division of Quantitative Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA., Zheng Z; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.; Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Zeng J; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Chasman DI; Division of Preventive Medicine Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Morris AP; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK., Caulfield MJ; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Hwang SJ; Population Sciences Branch, NHLBI Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University, Boston, MA, USA., Kooner JS; National Heart and Lung Institute, Imperial College London, London, UK., Conen D; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada., Attia JR; Faculty of Health and Medicine, University of Newcastle, New Lambton Heights, Newcastle, New South Wales, Australia., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kristiansson K; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland., Schmidt R; Department of Neurology/Medical University Graz, Graz, Austria., Hicks AA; Institute for Biomedicine, Eurac Research, Bolzano, Italy.; University of Lübeck, Lübeck, Germany., Pramstaller PP; Institute for Biomedicine, Eurac Research, Bolzano, Italy.; University of Lübeck, Lübeck, Germany., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Risch L; Faculty of Medical Sciences, Private University of the Principality of Liechtenstein, Triesen, Liechtenstein.; Department of Laboratory Medicine, Dr. Risch Anstalt, Vaduz, Liechtenstein., Gyllensten U; Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Melander O; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.; Department of Internal Medicine, Skåne University Hospital, Malmö, Sweden., Riese H; Interdisciplinary Center Psychopathology and Emotional Regulation (ICPE), Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wilson JF; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, Scotland.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland., Campbell H; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, Scotland., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Psaty BM; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Systems and Population Health, University of Washington, Seattle, WA, USA., Lu Y; Vanderbilt Genetic Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Rice KM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Vollenweider P; Department of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Sundström J; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.; The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia., Langenberg C; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.; Computational Medicine, Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, Berlin, Germany.; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, UK.; Leicester NIHR Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Giedraitis V; Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., Luan J; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Tuomilehto J; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Kutalik Z; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Ripatti S; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.; Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Salomaa V; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland., Girotto G; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health - IRCCS, Burlo Garofolo, Trieste, Italy., Trompet S; Department Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Netherlands Heart Institute, Utrecht, the Netherlands., van der Harst P; Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Ridker PM; Division of Preventive Medicine Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Giulianini F; Division of Preventive Medicine Brigham and Women's Hospital, Boston, MA, USA., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland., Goel A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Watkins H; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Harris SE; Lothian Birth Cohorts Group, Department of Psychology, The University of Edinburgh, Edinburgh, UK., Deary IJ; Lothian Birth Cohorts Group, Department of Psychology, The University of Edinburgh, Edinburgh, UK., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Keavney BD; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Manchester Heart Institute, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland.; Centre for Genomic and Experimental Medicine, IGC, University of Edinburgh, Edinburgh, UK., Campbell A; Centre for Genomic and Experimental Medicine, IGC, University of Edinburgh, Edinburgh, UK.; Usher Institute, University of Edinburgh, Edinburgh, UK., Boehnke M; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Scott LJ; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Boutin T; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland., Mamasoula C; Population Health Sciences Institute, Newcastle University, Newcastle, UK., Järvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Unit of Primary Health Care, Oulu University Hospital, OYS, Oulu, Finland., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Lehrstuhl für Epidemiologie, Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie (IBE), Ludwig-Maximilians-Universität München, Neuherberg, Germany., Gieger C; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Lakatta EG; Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Cucca F; Institute of Genetic and Biomedical Research, National Research Council (CNR), Monserrato, Italy., Hui J; Busselton Population Medical Research Institute, Perth, Western Australia, Australia.; School of Population and Global Health, The University of Western Australia, Nedlands, Western Australia, Australia., Knekt P; Population Health Unit, Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland., Enroth S; Department of Immunology, Genetics, and Pathology, Biomedical Center, Science for Life Laboratory (SciLifeLab) Uppsala, Uppsala University, Uppsala, Sweden., De Borst MH; Department of Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Polašek O; University of Split School of Medicine, Split, Croatia.; Algebra University College, Zagreb, Croatia., Concas MP; Institute for Maternal and Child Health - IRCCS, Burlo Garofolo, Trieste, Italy., Catamo E; Institute for Maternal and Child Health - IRCCS, Burlo Garofolo, Trieste, Italy., Cocca M; Institute for Maternal and Child Health - IRCCS, Burlo Garofolo, Trieste, Italy., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria., Schmidt H; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria., Spedicati B; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Waldenberger M; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Strachan DP; Population Health Sciences Institute St George's, University of London, London, UK., Laan M; Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany., Dörr M; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Kopavogur, Iceland., Cook JP; Department of Health Data Science, University of Liverpool, Liverpool, UK., Ruggiero D; IRCCS Neuromed, Pozzilli, Italy.; Institute of Genetics and Biophysics - 'A. Buzzati-Traverso', National Research Council of Italy, Naples, Italy., Kolcic I; Algebra University College, Zagreb, Croatia.; Department of Public Health, University of Split School of Medicine, Split, Croatia., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Traglia M; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Raitakari OT; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Johnson AD; Population Sciences Branch, NHLBI Framingham Heart Study, Framingham, MA, USA.; The Framingham Heart Study, Framingham, MA, USA., Newton-Cheh C; Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Brown MJ; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Dominiczak AF; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK., Sever PJ; International Centre for Circulatory Health, Imperial College London, London, UK., Poulter N; School of Public Health, Imperial College London, London, UK., Chambers JC; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore., Elosua R; Hospital del Mar Research Institute (IMIM), Barcelona, Spain.; CIBER Enfermedades Cardiovasculares (CIBERCV), Barcelona, Spain.; Faculty of Medicine, University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain., Siscovick D; New York Academy of Medicine, New York, NY, USA., Esko T; Institute of Genomics, University of Tartu, Tartu, Estonia., Metspalu A; Institute of Genomics, University of Tartu, Tartu, Estonia., Strawbridge RJ; Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.; Health Data Research UK, Glasgow, UK.; Division of Cardiovascular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Kuopio, Finland., Hamsten A; Division of Cardiovascular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Hottenga JJ; Department of Biological Psychology, Faculty of Behavioural and Movement Sciences, Vrije Universiteit, Amsterdam, the Netherlands., de Geus E; Department of Biological Psychology, Faculty of Behavioural and Movement Sciences, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam University Medical Centre, Amsterdam, the Netherlands., Morris AD; Data Science, University of Edinburgh, Edinburgh, UK.; Health Data Research UK, London, UK., Palmer CNA; Population Health and Genomics, School of Medicine, University of Dundee, Dundee, UK., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Milaneschi Y; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Psychiatry, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Marten J; Centre for Genomic and Experimental Medicine, IGC, University of Edinburgh, Edinburgh, UK., Wright A; Centre for Genomic and Experimental Medicine, IGC, University of Edinburgh, Edinburgh, UK., Zeggini E; Institute of Translational Genomics, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Technical University of Munich (TUM) and Klinikum Rechts der Isar, TUM School of Medicine, Munich, Germany., Howson JMM; Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., O'Donnell CJ; VA Boston Healthcare System, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Spector T; Department of Twin Research, King's College London, London, UK., Nalls MA; Center for Alzheimer's and Related Dementias, NIA/NINDS, NIH, Bethesda, MD, USA.; Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD, USA.; DataTecnica LLC, Washington, DC, USA., Simonsick EM; Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Liu Y; Division of Cardiology, Duke University School of Medicine, Durham, NC, USA., van Duijn CM; Nuffield Department of Population Health, Big Data Institute, University of Oxford, Oxford, UK., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK., Danesh JN; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Department of Human Genetics, The Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Menni C; Department of Twin Research and Genetic Epidemiology, London, UK., Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Khaw KT; Department of Public Health and Primary Care, University of Cambridge School of Clinical Medicine, Cambridge, UK., Sun YV; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, Georgia, USA.; VA Atlanta Healthcare System, Decatur, GA, USA., Wilson PWF; Emory Clinical Cardiovascular Research Institute, Atlanta, GA, USA.; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA., Cho K; Division of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Cardiovascular Health Research Unit, Departments of Medicine and Epidemiology, University of Washington, Seattle, WA, USA., Visscher PM; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Denny JC; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Levy D; Population Sciences Branch, NHLBI Framingham Heart Study, Framingham, MA, USA.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Edwards TL; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. todd.l.edwards@vumc.org., Munroe PB; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Warren HR; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. h.r.warren@qmul.ac.uk.; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. h.r.warren@qmul.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2024 May; Vol. 56 (5), pp. 778-791. Date of Electronic Publication: 2024 Apr 30.
Autor:
Wang H; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. hwang@bwh.harvard.edu.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA. hwang@bwh.harvard.edu., Noordam R; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands., Cade BE; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Schwander K; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Lee J; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Joint Carnegie Mellon University-University of Pittsburgh PhD Program in Computational Biology, Pittsburgh, PA, USA.; Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Pittsburgh Center for Evolutionary Biology and Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Sung YJ; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Manning AK; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Aschard H; Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.; Centre de Bioinformatique, Biostatistique et Biologie Intégrative (C3BI), Institut Pasteur, Paris, France., Kilpeläinen TO; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Environmental Medicine and Public Health, The Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ilkov M; Icelandic Heart Association, Kopavogur, Iceland., Brown MR; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Horimoto AR; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, Brazil., Richard M; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Bartz TM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Biostatistics, University of Washington, Seattle, WA, USA., Vojinovic D; Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands., Lim E; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Nierenberg JL; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA., Liu Y; Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute Duke University School of Medicine, Durham, NC, USA., Chitrala K; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA., Musani SK; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Franceschini N; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Alver M; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.; Department of Genetic Medicine and Development, University of Geneva, Geneva, Switzerland., Zee PC; Division of Sleep Medicine, Department of Neurology, Northwestern University, Chicago, IL, USA., Harris SE; Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Munroe PB; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, London, UK., Palmer ND; Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Kühnel B; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany.; German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany., Wen W; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA., Hall KA; School of Public Health, The University of Adelaide, Adelaide, SA, Australia., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., O'Connell J; Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.; Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Eiriksdottir G; Icelandic Heart Association, Kopavogur, Iceland., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Arking DE; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Chen H; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Center for Precision Health, School of Public Health & School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Krieger JE; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, Brazil., Schreiner PJ; Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Sidney S; Kaiser Permanente Northern California, Oakland, CA, USA., Shikany JM; Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Rice K; Department of Biostatistics, University of Washington, Seattle, WA, USA., Chen YI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Gharib SA; Computational Medicine Core, Center for Lung Biology, UW Medicine Sleep Center, Department of Medicine, University of Washington, Seattle, WA, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Luik AI; Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands., Ikram MA; Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Uitterlinden AG; Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, the Netherlands., Amin N; Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands., Xu H; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Levy D; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute Framingham Heart Study, Framingham, MA, USA., He J; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA., Lohman KK; Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute Duke University School of Medicine, Durham, NC, USA., Zonderman AB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Rice TK; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA., Sims M; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Wilson G; JHS Graduate Training and Education Center, Jackson State University, Jackson, MS, USA., Sofer T; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Palmas W; Division of General Medicine, Department of Medicine, Columbia University, New York, NY, USA., Yao J; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Biermasz NR; Division of Endocrinology, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands., Martin LW; George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Barac A; MedStar Heart and Vascular Institute, Washington, DC, USA., Wallace RB; Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA, USA., Gottlieb DJ; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; VA Boston Healthcare System, Boston, MA, USA., Komulainen P; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Heikkinen S; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland.; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., Mägi R; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Milani L; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Metspalu A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Starr JM; Alzheimer Scotland Dementia Research Centre, The University of Edinburgh, Edinburgh, UK., Milaneschi Y; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit, Amsterdam, HJ, The Netherlands., Waken RJ; Division of Cardiology, Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA., Gao C; Molecular Genetics and Genomics Program, Wake Forest School of Medicine, Winston-Salem, NC, USA., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Neuherberg, Germany., Strauch K; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Munich, Germany., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Roenneberg T; Institute and Polyclinic for Occupational-, Social- and Environmental Medicine, LMU Munich, Munich, Germany., Völker U; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany.; German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany., Dörr M; German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA., Mukherjee S; Sleep Health Service, Respiratory and Sleep Services, Southern Adelaide Local Health Network, Adelaide, SA, Australia.; Adelaide Institute for Sleep Health, Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Adelaide, SA, Australia., Hillman DR; Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Perth, WA, Australia., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Wagenknecht LE; Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany., Grabe HJ; Department Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA., Palmer LJ; School of Public Health, The University of Adelaide, Adelaide, SA, Australia., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Pereira AC; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, Brazil.; Department of Genetics, Harvard Medical School, Boston, MA, USA., Fornage M; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Cardiovascular Health Research Unit, Departments of Epidemiology and Health Services, University of Washington, Seattle, WA, USA., van Duijn CM; Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Kelly TN; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA., Evans MK; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA., Fox ER; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Zhu X; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Lakka TA; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Esko T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., North KE; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Deary IJ; Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Penninx BWJH; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit, Amsterdam, HJ, The Netherlands., Gauderman WJ; Division of Biostatistics, Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA., Rao DC; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA., Redline S; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Division of Pulmonary Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., van Heemst D; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands. d.van_heemst@lumc.nl.
Publikováno v:
Molecular psychiatry [Mol Psychiatry] 2021 Nov; Vol. 26 (11), pp. 6293-6304. Date of Electronic Publication: 2021 Apr 15.
Autor:
de Las Fuentes L; Cardiovascular Division, Department of Medicine, Washington University, St. Louis, MO, 63110, USA. lfuentes@wustl.edu.; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, 63110, USA. lfuentes@wustl.edu., Sung YJ; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, 63110, USA. yunju@wustl.edu., Noordam R; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, 2333ZA, The Netherlands., Winkler T; Department of Genetic Epidemiology, University of Regensburg, 93051, Regensburg, Germany., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, 63108, USA., Schwander K; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, 63110, USA., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Brown MR; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA., Manning A; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA, 02114, USA.; Department of Medicine, Harvard Medical School, Boston, MA, 02115, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.; Harvard Medical School, Boston, MA, 02115, USA., Aschard H; Department of Epidemiology, Harvard School of Public Health, Boston, MA, 02115, USA.; Centre de Bioinformatique, Biostatistique et Biologie Intégrative (C3BI), Institut Pasteur, Paris, 75724, France., Bartz TM; Cardiovascular Health Research Unit, Biostatistics and Medicine, University of Washington, Seattle, WA, 98101, USA., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Campbell A; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Cheng CY; Ocular Epidemiology, Singapore Eye Research Institute, Singapore National Ecy Centre, Singapore, 169856, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, 169857, Singapore., Dorajoo R; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore., Hartwig FP; Postgraduate Programme in Epidemiology, Federal University of Pelotas, Pelotas, RS, 96020-220, Brazil.; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, BS8 2BN, UK., Horimoto ARVR; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, SP, 5403000, Brazil., Li C; Epidemiology and Biostatistics, University of Georgia at Athens College of Public Health, Athens, GA, 30602, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2333ZA, Netherlands., Liu Y; Public Health Sciences, Epidemiology and Prevention, Wake Forest University Health Sciences, Winston-Salem, NC, 27157, USA., Marten J; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Musani SK; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, 39213, USA., Ntalla I; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA., Richard M; Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, 70808, USA., Sim X; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore., Smith AV; Department of Biostatistics, University of Michigan, Ann Arbor, MI, 48109, USA.; Icelandic Heart Association, Kopavogur, 201, Iceland., Tajuddin SM; Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA., Tayo BO; Department of Public Health Sciences, Loyola University Chicago, Maywood, IL, 60153, USA., Vojinovic D; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Warren HR; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.; NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, London, EC1M 6BQ, UK., Xuan D; Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA., Alver M; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia.; Department of Biotechnology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, 51010, Estonia., Boissel M; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, 59000, France., Chai JF; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore., Chen X; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, 17177, Sweden., Christensen K; Unit of Epidemiology, Biostatistics and Biodemography, Department of Public Health, Southern Denmark University, Odense, 5000, Denmark., Divers J; Biostatistical Sciences, Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Evangelou E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, 45110, Greece., Gao C; Molecular Genetics and Genomics Program, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Girotto G; Medical Genetics, Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, 34100, Italy.; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Trieste, 34100, Italy., Harris SE; Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., He M; Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China., Hsu FC; Biostatistical Sciences, Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Kühnel B; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Germany., Laguzzi F; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, 17177, Sweden., Li X; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, 44106, USA.; Department of Mathematics and Statistics, University of Minnesota, Duluth, MN, 55812, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, 33520, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, University of Tampere, Tampere, 33014, Finland., Nolte IM; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, 9700RB, The Netherlands., Poveda A; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Malmö, Skåne, 205 02, Sweden., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland., Riaz M; College of Medicine, Biological Sciences and Psychology, Health Sciences, The Infant Mortality and Morbidity Studies (TIMMS), Leicester, LE1 7RH, UK., Rueedi R; Department of Computational Biology, University of Lausanne, Lausanne, 1011, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA., Snieder H; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, 9700RB, The Netherlands., Sofer T; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, 02115, USA., Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, 1628655, Japan., Verweij N; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, 9700, The Netherlands., Ware EB; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 9713GZ, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Health), Partner Site Greifswald, 17475, Greifswald, Germany., Yanek LR; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA., Amin N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Arking DE; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Arnett DK; Dean's Office, University of Kentucky College of Public Health, Lexington, KY, 40536, USA., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, 1011, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, 77030, USA., Brody JA; Cardiovascular Health Research Unit, Medicine, University of Washington, Seattle, WA, 98101, USA., Broeckel U; Section of Genomic Pediatrics, Department of Pediatrics, Medicine and Physiology, Medical College of Wisconsin, Milwaukee, WI, 53226, USA., Brumat M; Medical Genetics, Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, 34100, Italy., Burke G; Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, 27109, USA., Cabrera CP; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.; NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, London, EC1M 6BQ, UK., Canouil M; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, 59000, France., Chee ML; Statistics Unit, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 169856, Singapore., Chen YI; The Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA., Cocca M; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Trieste, 34100, Italy., Connell J; Ninewells Hospital & Medical School, University of Dundee, Dundee, Scotland, DD1 9SY, UK., de Silva HJ; Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Eiriksdottir G; Icelandic Heart Association, Kopavogur, 201, Iceland., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Fisher V; Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA., Forrester T; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, JMAAW15, Jamaica., Fox EF; Cardiology, Medicine, University of Mississippi Medical Center, Jackson, MS, 39216, USA., Friedlander Y; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, 91120, Israel., Gao H; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, W2 1PG, UK., Gigante B; Cardiovascular Unit, Bioclinicum, Department of Medicine, Karolinska Hospital, Stockholm, 17164, Sweden.; Division of Cardiovascular Medicine, Department of Clinical Sciences, Danderyd University Hospital, Stockholm, 18288, Sweden., Giulianini F; Brigham and Women's Hospital, Boston, MA, 02215, USA., Gu CC; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, 63110, USA., Gu D; Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, MD, 20892, USA., He J; Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, 70112, USA.; Medicine, Tulane University School of Medicine, New Orleans, LA, 70112, USA., Heikkinen S; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, 70211, Finland.; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, 70211, Finland., Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore.; Khoo Teck Puat - National University Children's Medical Institute, National University Health System, Singapore, 119228, Singapore., Hunt S; Cardiovascular Genetics, Department of Internal Medicine, University of Utah, Salt Lake City, UT, 84108, USA.; Weill Cornell Medicine in Qatar, Doha, Qatar., Ikram MA; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Irvin MR; Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, 35294, USA., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, 33521, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, University of Tampere, Tampere, 33014, Finland., Kavousi M; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Khor CC; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore.; Department of Biochemistry, National University of Singapore, Singapore, 117596, Singapore., Kilpeläinen TO; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, DK-2200, Denmark.; Department of Environmental Medicine and Public Health, The Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Koh WP; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore.; Health Services and Systems Research, Duke-NUS Medical School, Singapore, 169857, Singapore., Komulainen P; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland., Kraja AT; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, 63108, USA., Krieger JE; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, SP, 5403000, Brazil., Langefeld CD; Biostatistical Sciences, Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Li Y; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, 63110, USA., Liang J; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, 44106, USA., Liewald DCM; Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Liu CT; Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA., Liu J; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore.; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore., Lohman KK; Public Health Sciences, Biostatistics and Data Science, Wake Forest University Health Sciences, Winston-Salem, NC, 27157, USA., Mägi R; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia., McKenzie CA; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, JMAAW15, Jamaica., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, 80333, Munich, Germany., Metspalu A; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia.; Department of Biotechnology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, 51010, Estonia., Milaneschi Y; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, 1081 BT, The Netherlands., Milani L; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2333ZA, Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, 2333ZA, Netherlands., Nalls MA; Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, 20895, USA.; Data Tecnica International, Glen Echo, MD, 20812, USA., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, LE3 9QP, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, LE3 9QP, UK., Norris JM; Department of Epidemiology, University of Colorado Denver, Aurora, CO, 80045, USA., O'Connell J; Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.; Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Ogunniyi A; Department of Medicine, University of Ibadan, Ibadan, Oyo, Nigeria., Padmanabhan S; British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8TA, UK., Palmer ND; Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, 17177, Sweden., Perls T; Department of Medicine, Geriatrics Section, Boston Medical Center, Boston University School of Medicine, Boston, MA, 02118, USA., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, 85764, Neuherberg, Germany., Petersmann A; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475, Greifswald, Germany., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Polasek O; University of Split School of Medicine, Split, Croatia.; University Hospital Split, Split, Croatia.; Psychiatric Hospital 'Sveti Ivan', Zagreb, Croatia., Porteous DJ; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.; Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Raffel LJ; Division of Genetic and Genomic Medicine, Department of Pediatrics, University of California, Irvine, CA, 92868, USA., Rice TK; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, 63110, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA., Rudan I; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, EH8 9AG, UK., Rueda-Ochoa OL; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Sabanayagam C; Ocular Epidemiology, Singapore Eye Research Institute, Singapore National Ecy Centre, Singapore, 169856, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, 169857, Singapore., Salako BL; Department of Medicine, University of Ibadan, Ibadan, Oyo, Nigeria., Schreiner PJ; Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, 55454, USA., Shikany JM; Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, 25249, USA., Sidney SS; Division of Research, Kaiser Permanente of Northern California, Oakland, CA, USA., Sims M; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, 39213, USA., Sitlani CM; Cardiovascular Health Research Unit, Medicine, University of Washington, Seattle, WA, 98101, USA., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Starr JM; Alzheimer Scotland Dementia Research Centre, The University of Edinburgh, Edinburgh, EH8 9AZ, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Germany.; Institute of Medical Informatics Biometry and Epidemiology, Ludwig-Maximilians-Universitat Munchen, 80539, Munich, Germany., Swertz MA; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, 9700RB, The Netherlands., Teumer A; DZHK (German Centre for Cardiovascular Health), Partner Site Greifswald, 17475, Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, 17475, Greifswald, Germany., Tham YC; Ocular Epidemiology, Singapore Eye Research Institute, Singapore National Ecy Centre, Singapore, 169856, Singapore., Uitterlinden AG; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Vaidya D; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA., van der Ende MY; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, 9700, The Netherlands., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, 85764, Neuherberg, Germany., Wang L; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, 63108, USA., Wang YX; Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Ophthalmology and Visual Science Key Lab, Beijing Tongren Hospital, Capital Medical University, 100730, Beijing, China., Wei WB; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, 100730, Beijing, China., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Wen W; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA., Yao J; The Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA., Yu B; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Yu C; Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China., Yuan JM; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, 15261, USA.; Division of Cancer Control and Population Sciences, UPMC Hillman Cancer, , University of Pittsburgh, Pittsburgh, PA, 15232, USA., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Zonderman AB; Behavioral Epidemiology Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA., Becker DM; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA., Bowden DW; Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Deary IJ; Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Dörr M; DZHK (German Centre for Cardiovascular Health), Partner Site Greifswald, 17475, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, 17475, Greifswald, Germany., Esko T; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, 51010, Estonia.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Boston, MA, 02142, USA., Freedman BI; Section on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston-, Salem, NC, 27157, USA., Froguel P; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, 59000, France.; Department of Genomics of Common Disease, Imperial College London, London, W12 0NN, UK., Gasparini P; Medical Genetics, Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, 34100, Italy.; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Trieste, 34100, Italy., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), 85764, Neuherberg, Germany., Jonas JB; Department of Ophthalmology, Medical Faculty Mannheim, University Heidelberg, 68167, Mannheim, Germany.; Beijing Institute of Ophthalmology, Beijing Ophthalmology and Visual Science Key Lab, Beijing Tongren Eye Center, Capital Medical University, 100730, Beijing, China., Kammerer CM; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, 15261, USA., Kato N; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, 1628655, Japan., Lakka TA; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, 70211, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, 70211, Finland., Leander K; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, 17177, Sweden., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, 33520, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, University of Tampere, Tampere, 33014, Finland., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, 17177, Sweden., Marques-Vidal P; Department of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, 1011, Switzerland., Penninx BWJH; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, 1081 BT, The Netherlands., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, LE3 9QP, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, LE3 9QP, UK., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, 9700, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Ultrecht, The Netherlands., Wagenknecht LE; Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, 27109, USA., Wu T; Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA., Zhu X; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, 44106, USA., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA., Cooper RS; Department of Public Health Sciences, Loyola University Chicago, Maywood, IL, 60153, USA., Correa A; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, 39213, USA., Evans MK; Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA., Gudnason V; Icelandic Heart Association, Kopavogur, 201, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Horta BL; Postgraduate Programme in Epidemiology, Federal University of Pelotas, Pelotas, RS, 96020-220, Brazil., Kelly TN; Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, 70112, USA., Kritchevsky SB; Sticht Center for Health Aging and Alzheimer's Prevention, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Levy D; NHLBI Framingham Heart Study, Framingham, MA, 01702, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, 20892, USA., Palmas WR; Division of General Medicine, Department of Medicine, Columbia University Medical Center, New York, NY, 10032, USA., Pereira AC; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, SP, 5403000, Brazil., Province MM; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, 63108, USA., Psaty BM; Cardiovascular Health Research Unit, Epidemiology, Medicine and Health Services, University of Washington, Seattle, WA, 98101, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, 98101, USA., Ridker PM; Harvard Medical School, Boston, MA, 02115, USA.; Brigham and Women's Hospital, Boston, MA, 02215, USA., Rotimi CN; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Tai ES; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore.; Health Services and Systems Research, Duke-NUS Medical School, Singapore, 169857, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore., van Dam RM; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore., van Duijn CM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Wong TY; Ocular Epidemiology, Singapore Eye Research Institute, Singapore National Ecy Centre, Singapore, 169856, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, 169857, Singapore., Rice K; Department of Biostatistics, University of Washington, Seattle, WA, 98195, USA., Gauderman WJ; Biostatistics, Preventive Medicine, University of Southern California, Los Angeles, CA, 90032, USA., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., North KE; Epidemiology, University of North Carolina Gilling School of Global Public Health, Chapel Hill, NC, 27514, USA., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109, USA., Caulfield MJ; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.; NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, London, EC1M 6BQ, UK., Elliott P; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, W2 1PG, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, W2 1PG, UK., Munroe PB; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.; NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, London, EC1M 6BQ, UK., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Malmö, Skåne, 205 02, Sweden.; Department of Public Health & Clinical Medicine, Umeå University, Umeå, Västerbotten, 901 85, Sweden., Rao DC; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, 63110, USA., Fornage M; Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, 70808, USA.
Publikováno v:
Molecular psychiatry [Mol Psychiatry] 2021 Jun; Vol. 26 (6), pp. 2111-2125. Date of Electronic Publication: 2020 May 05.
Autor:
Sargurupremraj M; University of Bordeaux, Inserm, Bordeaux Population Health Research Center, team VINTAGE, UMR 1219, 33000, Bordeaux, France., Suzuki H; Tohoku Medical Megabank Organization, Tohoku University, 2-1, Seiryo, Aoba, Sendai, 980-8573, Japan.; Department of Cardiovascular Medicine, Tohoku University Hospital, 1-1, Seiryo, Aoba, Sendai, 980-8574, Japan.; Department of Brain Sciences, Imperial College London, London, W12 0NN, UK., Jian X; University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX, 77030, USA.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, 78229, USA., Sarnowski C; Department of Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA., Evans TE; Department of Clinical Genetics, Erasmus MC, 3015 GE, Rotterdam, The Netherlands.; Department of Radiology & Nuclear Medicine, Erasmus MC, 3015 GE, Rotterdam, The Netherlands., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, 98101, USA., Eiriksdottir G; Icelandic Heart Association, IS-201, Kópavogur, Iceland., Sakaue S; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan.; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; Department of Allergy and Rheumatology, Graduate School of Medicine, the University of Tokyo, Tokyo, 113-0033, Japan., Terzikhan N; Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam, The Netherlands., Habes M; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, 78229, USA.; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Institute for Community Medicine, University Medicine Greifswald, 17475, Greifswald, Germany., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109-2029, USA., Armstrong NJ; Mathematics and Statistics, Murdoch University, Murdoch, WA, 6150, Australia., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, 8036, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, 8036, Graz, Austria., Yanek LR; GeneSTAR Research Program, Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Hagenaars SP; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Social Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 8AF, UK., Kumar RB; Department of Public Health Sciences, University of California at Davis, Davis, CA, 95616, USA., van den Akker EB; Section of Molecular Epidemiology, Biomedical Sciences, Leiden university Medical Center, 2333 ZA, Leiden, The Netherlands.; Pattern Recognition & Bioinformatics, Delft University of Technology, Delft, NL, 2629 HS, USA.; Leiden Computational Biology Centre, Leiden University Medical Centre, 2333 ZA, Leiden, The Netherlands., McWhirter RE; Centre for Law and Genetics, Faculty of Law, University of Tasmania, Hobart, TAS, 7005, Australia.; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, 7000, Australia., Trompet S; Department of Internal Medicine, section of gerontology and geriatrics, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands.; Department of Cardiology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Mishra A; University of Bordeaux, Inserm, Bordeaux Population Health Research Center, team VINTAGE, UMR 1219, 33000, Bordeaux, France., Saba Y; University of Bordeaux, Inserm, Bordeaux Population Health Research Center, team VINTAGE, UMR 1219, 33000, Bordeaux, France.; Gottfried Schatz Research Center, Department of Molecular Biology and Biochemistry, Medical University of Graz, 8010, Graz, Austria., Satizabal CL; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, 78229, USA.; Boston University and the NHLBI's Framingham Heart Study, Boston, MA, 02215, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, 02118, USA., Beaudet G; University of Bordeaux, IMN, UMR 5293, 33000, Bordeaux, France., Petit L; University of Bordeaux, IMN, UMR 5293, 33000, Bordeaux, France., Tsuchida A; University of Bordeaux, IMN, UMR 5293, 33000, Bordeaux, France., Zago L; University of Bordeaux, IMN, UMR 5293, 33000, Bordeaux, France., Schilling S; University of Bordeaux, Inserm, Bordeaux Population Health Research Center, team VINTAGE, UMR 1219, 33000, Bordeaux, France., Sigurdsson S; Icelandic Heart Association, IS-201, Kópavogur, Iceland., Gottesman RF; Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Lewis CE; University of Alabama at Birmingham School of Medicine, Birmingham, AL, 35233, USA., Aggarwal NT; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, 60612, USA., Lopez OL; Departments of Neurology and Psychiatry, University of Pittsburgh, Pittsburgh, PA, 15213, USA., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109-2029, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Valdés Hernández MC; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, EH16 4SB, UK.; Row Fogo Centre for Ageing and The Brain, University of Edinburgh, Edinburgh, EH8 9JZ, UK., van der Grond J; Department of Radiology, Leiden University medical Center, 2333 ZA, Leiden, The Netherlands., Wright MJ; Queensland Brain Institute, The University of Queensland, St Lucia, QLD, 4072, Australia.; Centre for Advanced Imaging, The University of Queensland, St Lucia, QLD, 4072, Australia., Knol MJ; Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam, The Netherlands., Dörr M; Department of Internal Medicine B, University Medicine Greifswald, 17475, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, 17475, Greifswald, Germany., Thomson RJ; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, 7000, Australia.; Centre for Research in Mathematics and Data Science, Western Sydney University, Penrith, NSW, 2751, Australia., Bordes C; University of Bordeaux, Inserm, Bordeaux Population Health Research Center, team VINTAGE, UMR 1219, 33000, Bordeaux, France., Le Grand Q; University of Bordeaux, Inserm, Bordeaux Population Health Research Center, team VINTAGE, UMR 1219, 33000, Bordeaux, France., Duperron MG; University of Bordeaux, Inserm, Bordeaux Population Health Research Center, team VINTAGE, UMR 1219, 33000, Bordeaux, France., Smith AV; Icelandic Heart Association, IS-201, Kópavogur, Iceland., Knopman DS; Mayo Clinic, Rochester, MN, 55905, USA., Schreiner PJ; University of Minnesota School of Public Health, Minneapolis, MN, 55455, USA., Evans DA; Department of Internal Medicine, Rush University Medical Center, Chicago, IL, 60612, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Pediatrics at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA., Beiser AS; Department of Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA.; Boston University and the NHLBI's Framingham Heart Study, Boston, MA, 02215, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, 02118, USA., Maniega SM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, EH16 4SB, UK., Beekman M; Section of Molecular Epidemiology, Biomedical Sciences, Leiden university Medical Center, 2333 ZA, Leiden, The Netherlands., Trollor J; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, 2052, Australia.; Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales, Sydney, NSW, 2052, Australia., Stott DJ; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK., Vernooij MW; Department of Radiology & Nuclear Medicine, Erasmus MC, 3015 GE, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam, The Netherlands., Wittfeld K; German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, 17489, Greifswald, Germany., Niessen WJ; Department of Radiology & Nuclear Medicine, Erasmus MC, 3015 GE, Rotterdam, The Netherlands.; Faculty of Applied Sciences, Delft University of Technology, Delft, NL, 2629 HS, USA., Soumaré A; University of Bordeaux, Inserm, Bordeaux Population Health Research Center, team VINTAGE, UMR 1219, 33000, Bordeaux, France., Boerwinkle E; University of Texas Health Science Center at Houston School of Public Health, Houston, TX, 77030, USA., Sidney S; Kaiser Permanente Division of Research, Oakland, CA, 94612, USA., Turner ST; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, 55905, USA., Davies G; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, 8036, Graz, Austria.; Department of Psychology, University of Edinburgh, Edinburgh, EH8 9JZ, UK., Thalamuthu A; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Pediatrics at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA., Völker U; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475, Greifswald, Germany., van Buchem MA; Row Fogo Centre for Ageing and The Brain, University of Edinburgh, Edinburgh, EH8 9JZ, UK., Bryan RN; The University of Texas at Austin Dell Medical School, Austin, TX, 78712, USA., Dupuis J; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, 78229, USA.; Department of Cardiology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Bastin ME; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, 8036, Graz, Austria.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, 48104, USA., Ames D; National Ageing Research Institute Royal Melbourne Hospital, Parkville, VIC, 3052, Australia.; Academic Unit for Psychiatry of Old Age, University of Melbourne, St George's Hospital, Kew, VIC, 3101, Australia., Teumer A; Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam, The Netherlands.; Department of Internal Medicine B, University Medicine Greifswald, 17475, Greifswald, Germany., Amouyel P; Inserm U1167, 59000, Lille, France.; Department of Epidemiology and Public Health, Pasteur Institute of Lille, 59000, Lille, France., Kwok JB; Brain and Mind Centre - The University of Sydney, Camperdown, NSW, 2050, Australia.; School of Medical Sciences, University of New South Wales, Sydney, NSW, 2052, Australia., Bülow R; Department of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, 17489, Greifswald, Germany., Deary IJ; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, 8036, Graz, Austria.; Department of Psychology, University of Edinburgh, Edinburgh, EH8 9JZ, UK., Schofield PR; School of Medical Sciences, University of New South Wales, Sydney, NSW, 2052, Australia.; Neuroscience Research Australia, Randwick, NSW, 2031, Australia., Brodaty H; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Pediatrics at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.; Dementia Centre for Research Collaboration, University of New South Wales, Sydney, NSW, 2052, Australia., Jiang J; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Pediatrics at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA., Tabara Y; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, 606-8501, Japan., Setoh K; Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, 606-8501, Japan., Miyamoto S; Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, 606-8501, Japan., Yoshida K; Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, 606-8501, Japan., Nagata M; Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, 606-8501, Japan., Kamatani Y; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan., Matsuda F; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, 606-8501, Japan., Psaty BM; Departments of Epidemiology, Medicine and Health Services, University of Washington, Seattle, WA, 98195, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, 98101, USA., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, 60612, USA., De Jager PL; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, 10032, USA.; Program in Population and Medical Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Mosley TH; Memory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson, MS, 39216, USA., Sachdev PS; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Pediatrics at Harbor-UCLA Medical Center, Torrance, CA, 90502, USA.; Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, NSW, 2031, Australia., Schmidt R; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109-2029, USA., Warren HR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, E1 4NS, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, EC1M 6BQ, UK., Evangelou E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, SW7 2AZ, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Mpizani, 455 00, Greece., Trégouët DA; University of Bordeaux, Inserm, Bordeaux Population Health Research Center, team VINTAGE, UMR 1219, 33000, Bordeaux, France., Ikram MA; Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam, The Netherlands., Wen W; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, 2052, Australia., DeCarli C; Department of Neurology and Center for Neuroscience, University of California at Davis, Sacramento, CA, 95817, USA., Srikanth VK; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, 7000, Australia.; Peninsula Clinical School, Central Clinical School, Monash University, Melbourne, VIC, 3004, Australia., Jukema JW; Department of Cardiology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Slagboom EP; Section of Molecular Epidemiology, Biomedical Sciences, Leiden university Medical Center, 2333 ZA, Leiden, The Netherlands., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, 48109-2029, USA., Okada Y; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan.; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, 565-0871, Osaka, Japan., Mazoyer B; University of Bordeaux, IMN, UMR 5293, 33000, Bordeaux, France., Wardlaw JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, EH16 4SB, UK.; Row Fogo Centre for Ageing and The Brain, University of Edinburgh, Edinburgh, EH8 9JZ, UK.; MRC UK Dementia Research Institute at the University of Edinburgh, Edinburgh, EH8 9YL, UK., Nyquist PA; Department of Neurology, Johns Hopkins School of Medicine, Baltimone, MD, 21205, USA.; General Internal Medicine, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA., Mather KA; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, NSW, 2052, Australia.; Neuroscience Research Australia, Randwick, NSW, 2031, Australia., Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, 17475, Greifswald, Germany.; German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, 17475, Greifswald, Germany., Schmidt H; Gottfried Schatz Research Center, Department of Molecular Biology and Biochemistry, Medical University of Graz, 8010, Graz, Austria., Van Duijn CM; Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK., Gudnason V; Icelandic Heart Association, IS-201, Kópavogur, Iceland.; University of Iceland, Faculty of Medicine, 101, Reykjavík, Iceland., Longstreth WT Jr; Departments of Neurology and Epidemiology, University of Washington, Seattle, WA, 98104-2420, USA., Launer LJ; Laboratory of Epidemiology, Demography, and Biometry, National Institute of Aging, The National Institutes of Health, Bethesda, MD, 20892, USA.; Intramural Research Program/National Institute on Aging/National Institutes of Health, Bethesda, MD, 20892, USA., Lathrop M; University of McGill Genome Center, Montreal, QC, H3A 0G1, Canada., Seshadri S; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, 78229, USA.; Boston University and the NHLBI's Framingham Heart Study, Boston, MA, 02215, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, 02118, USA., Tzourio C; University of Bordeaux, Inserm, Bordeaux Population Health Research Center, team VINTAGE, UMR 1219, 33000, Bordeaux, France.; CHU de Bordeaux, Pole de santé publique, Service d'information médicale, 33000, Bordeaux, France., Adams HH; Department of Clinical Genetics, Erasmus MC, 3015 GE, Rotterdam, The Netherlands.; Department of Radiology & Nuclear Medicine, Erasmus MC, 3015 GE, Rotterdam, The Netherlands., Matthews PM; Department of Brain Sciences, Imperial College London, London, W12 0NN, UK.; UK Dementia Research Institute, London, WC1E 6BT, UK.; Data Science Institute, Imperial College London, London, SW7 2AZ, UK., Fornage M; University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX, 77030, USA. myriam.fornage@uth.tmc.edu., Debette S; University of Bordeaux, Inserm, Bordeaux Population Health Research Center, team VINTAGE, UMR 1219, 33000, Bordeaux, France. stephanie.debette@u-bordeaux.fr.; Department of Neurology, Boston University School of Medicine, Boston, MA, 02118, USA. stephanie.debette@u-bordeaux.fr.; Department of Neurology, CHU de Bordeaux, 33000, Bordeaux, France. stephanie.debette@u-bordeaux.fr.
Publikováno v:
Nature communications [Nat Commun] 2020 Dec 08; Vol. 11 (1), pp. 6285. Date of Electronic Publication: 2020 Dec 08.
Autor:
Surendran P; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Rutherford Fund Fellow, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Feofanova EV; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Lahrouchi N; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Amsterdam UMC, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences Amsterdam, Amsterdam, the Netherlands., Ntalla I; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Karthikeyan S; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Cook J; Department of Biostatistics, University of Liverpool, Liverpool, UK., Chen L; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Mifsud B; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar., Yao C; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Kraja AT; Division of Statistical Genomics, Department of Genetics and Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA., Cartwright JH; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Hellwege JN; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Giri A; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.; Division of Quantitative Sciences, Department of Obstetrics & Gynecology, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Tragante V; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Thorleifsson G; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Liu DJ; Institute of Personalized Medicine, Penn State College of Medicine, Hershey, PA, USA., Prins BP; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Stewart ID; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Cabrera CP; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Eales JM; Division of Cardiovascular Sciences, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK., Akbarov A; Division of Cardiovascular Sciences, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK., Auer PL; Joseph J Zilber School of Public Health, University of Wisconsin, Milwaukee, WI, USA., Bielak LF; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Braithwaite VS; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.; MRC Nutrition and Bone Health Group, University of Cambridge, Cambridge, UK.; MRC Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, Gambia., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Daw EW; Division of Statistical Genomics, Department of Genetics and Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA., Warren HR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Drenos F; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK., Nielsen SF; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Fauman EB; Internal Medicine Research Unit, Pfizer, Cambridge, MA, USA., Fava C; Department of Medicine, University of Verona, Verona, Italy.; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Ferreira T; The Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK., Foley CN; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; MRC Biostatistics Unit, University of Cambridge, Cambridge, UK., Franceschini N; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Gao H; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK., Giannakopoulou O; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Centre for Genomic Health, Queen Mary University of London, London, UK.; Division of Psychiatry, University College of London, London, UK., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Gudbjartsson DF; deCODE genetics/Amgen, Inc, Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland., Guo X; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK., Havulinna AS; Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK.; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Helgadottir A; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Huffman JE; MRC Human Genetics Unit, IGMM, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Hwang SJ; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Boston University and National Heart, Lung and Blood Institute Framingham Heart Study, Framingham, MA, USA., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Centre for Genomic Health, Life Sciences, Queen Mary University of London, London, UK., Kontto J; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Larson MG; Boston University and National Heart, Lung and Blood Institute Framingham Heart Study, Framingham, MA, USA.; Biostatistics Department, Boston University School of Public Health, Boston, MA, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Lindström J; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Lotta LA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Lu Y; The Charles Bronfman Institute for Personalized Medicine at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Mahajan A; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Malerba G; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy., Masca NGD; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Centre, Leicester, UK., Mei H; Department of Data Science, School of Population Health, University of Mississippi Medical Center, Jackson, MS, USA., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands., Mosen-Ansorena D; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, Ludwig-Maximilians-University Munich, Munich, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU, Munich, Germany., Paré G; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Paul DS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK., Perola M; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Clinical and Molecular Metabolism Research Program (CAMM), Faculty of Medicine, University of Helsinki, Helsinki, Finland., Poveda A; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden., Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Richard M; Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Richardson TG; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Sepúlveda N; Department of Infection Biology, Faculty of Tropical and Infectious Diseases, London School of Hygiene & Tropical Medicine, London, UK.; Centre of Statistics and Applications of University of Lisbon, Lisbon, Portugal., Sim X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Saw Swee Hock School of Public Health, National University of, Singapore, Singapore., Smith AV; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Smith JA; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Staley JR; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Stanáková A; University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Sulem P; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Thériault S; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.; Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University, Quebec City, Quebec, Canada., Thorsteinsdottir U; deCODE genetics/Amgen, Inc, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Trompet S; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden., Velez Edwards DR; Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Tennessee Valley Health Systems VA, Nashville, TN, USA., Veronesi G; Research Center in Epidemiology and Preventive Medicine, Department of Medicine and Surgery, University of Insubria, Varese, Italy., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, University Medicine and University of Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Willems SM; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Yao J; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Young R; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK., Yu B; Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA., Zhang W; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK., Zhao JH; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK., Zhao W; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA., Zhao W; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Evangelou E; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Aeschbacher S; Division of Cardiology, University Hospital, Basel, Switzerland., Asllanaj E; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; Department of Epidemiology, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands., Blankenberg S; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany.; University Medical Center Hamburg Eppendorf, Hamburg, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, Hamburg, Germany., Bonnycastle LL; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Brandslund I; Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Braund PS; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Centre, Leicester, UK., Burgess S; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; MRC Biostatistics Unit, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK., Cho K; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Christensen C; Medical Department, Lillebaelt Hospital, Vejle, Denmark., Connell J; University of Dundee, Ninewells Hospital & Medical School, Dundee, UK., Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Dominiczak AF; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, UK., Dörr M; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Eiriksdottir G; Icelandic Heart Association, Kopavogur, Iceland., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.; Department of Population Science and Experimental Medicine, Institute of Cardiovascular Science, University College London, London, UK., Gaziano JM; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Grove ML; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Hallmans G; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Have CT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Heiss G; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Jørgensen ME; Steno Diabetes Center, Copenhagen, Gentofte, Denmark., Jousilahti P; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Kajantie E; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; PEDEGO Research Unit, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Hospital for Children and Adolescents, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland., Kamat M; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK., Käräjämäki A; Department of Primary Health Care, Vaasa Central Hospital, Vaasa, Finland.; Diabetes Center, Vaasa Health Care Center, Vaasa, Finland., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Koistinen HA; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Kovesdy CP; Nephrology Section, Memphis VA Medical Center, Memphis, TN, USA., Kuulasmaa K; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Laatikainen T; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lannfelt L; Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., Lee IT; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan.; School of Medicine, , Chung Shan Medical University, Taichung, Taiwan.; College of Science, Tunghai University, Taichung, Taiwan., Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.; Department of Social Work, Tunghai University, Taichung, Taiwan., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Martin LW; George Washington University School of Medicine and Health Sciences, Washington DC, USA., Moitry M; Department of Public health, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France., Nadkarni G; The Charles Bronfman Institute for Personalized Medicine at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Neville MJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Palmer CNA; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland, UK., Papanicolaou GJ; Epidemiology Branch, NHLBI, Bethesda, MD, USA., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Peters J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Department of Immunology and Inflammation, Imperial College London, London, UK., Poulter N; International Centre for Circulatory Health, Imperial College London, London, UK., Rasheed A; Centre for Non-Communicable Diseases, Karachi, Pakistan., Rasmussen KL; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Rayner NW; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Mägi R; Institute of Genomics, University of Tartu, Tartu, Estonia., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden.; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Rettig R; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute of Physiology, University Medicine Greifswald, Karlsburg, Germany., Rossouw J; Division of Cardiovascular Sciences, NHLBI, Bethesda, MD, USA., Schreiner PJ; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA., Sever PS; National Heart and Lung Institute, Imperial College London, London, UK., Sigurdsson EL; Department of Family Medicine, University of Iceland, Reykjavik, Iceland.; Development Centre for Primary Health Care in Iceland, Reykjavik, Iceland., Skaaby T; Center for Clinical Research and Disease Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark., Sun YV; Department of Epidemiology, Emory University Rollins School of Public Health, Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, USA., Sundstrom J; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Thorgeirsson G; deCODE genetics/Amgen, Inc, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Department of Internal Medicine, Division of Cardiology, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland., Esko T; Institute of Genomics, University of Tartu, Tartu, Estonia.; Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Trabetti E; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy., Tsao PS; VA Palo Alto Health Care System, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA., Tuomi T; Folkhälsan Research Centre, Helsinki, Finland.; Department of Endocrinology, Helsinki University Central Hospital, Helsinki, Finland.; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden Institute for Molecular Medicine Helsinki (FIMM), Helsinki University, Helsinki, Finland., Turner ST; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA., Tzoulaki I; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Vaartjes I; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, University of Utrecht, University of Utrecht, Utrecht, the Netherlands.; Center for Circulatory Health, University Medical Center Utrecht, University of Utrecht, Utrecht, the Netherlands., Vergnaud AC; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Willer CJ; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Wilson PWF; Atlanta VAMC and Emory Clinical Cardiovascular Research Institute, Atlanta, GA, USA., Witte DR; Department of Public Health, Aarhus University, Aarhus, Denmark.; Danish Diabetes Academy, Odense, Denmark.; Steno Diabetes Center Aarhus, Aarhus, Denmark., Yonova-Doing E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Zhang H; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA., Aliya N; International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh., Almgren P; Department of Medicine, Lund University, Malmö, Sweden., Amouyel P; Univ Lille, U1167 - RID-AGE - Facteurs de Risque et Déterminants Moléculaires des Maladies Liées au Vieillissement, Lille, France.; INSERM, U1167, Lille, France.; CHU Lille, U1167, Lille, France.; Institut Pasteur de Lille, U1167, Lille, France., Asselbergs FW; Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.; Health Data Research UK, Institute of Health Informatics, University College London, London, UK., Barnes MR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Blakemore AI; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK.; Section of Investigative Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, UK., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Bots ML; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, University of Utrecht, University of Utrecht, Utrecht, the Netherlands.; Center for Circulatory Health, University Medical Center Utrecht, University of Utrecht, Utrecht, the Netherlands., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Buring JE; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Chambers JC; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Imperial College Healthcare NHS Trust, London, UK., Chen YI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Chowdhury R; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Non-communicable Disease Research (CNCR), Dhaka, Bangladesh., Conen D; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.; Cardiovascular Research Institute Basel, Basel, Switzerland., Correa A; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Davey Smith G; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Boer RA; 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Institute of Reproductive & Developmental Biology, Imperial College London, London, UK., Frossard P; Centre for Non-Communicable Diseases, Karachi, Pakistan., Gambaro G; Division of Nephrology, Department of Medicine, University of Verona, Verona, Italy., Gaunt TR; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Groop L; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden.; Institute for Molecular Medicine Helsinki (FIMM), Helsinki University, Helsinki, Finland., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute of Aging, Bethesda, MD, USA., Hayward C; MRC Human Genetics Unit, IGMM, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Hennig BJ; MRC Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, Gambia.; Wellcome Trust, London, UK., Herzig KH; Institute of Biomedicine, Medical Research Center (MRC), University of Oulu, and University Hospital Oulu, Oulu, Finland.; Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, Poznan, Poland., Ingelsson E; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA., Tuomilehto J; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Saudi Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.; National Institute of Public Health, Madrid, Spain., Järvelin MR; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK.; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Unit of Primary Care, Oulu University Hospital, Kajaanintie, Oulu, Finland.; Center for Life-Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Netherlands Heart Institute, Utrecht, the Netherlands., Kardia SLR; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Kee F; Centre for Public Health, Queens University Belfast, Belfast, UK., Kooner JS; National Institute for Health Research (NIHR) Imperial Biomedical Research Centre, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; National Heart and Lung Institute, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK., Kooperberg C; Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, WA, USA., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute of Aging, Bethesda, MD, USA., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Loos RJF; The Charles Bronfman Institute for Personalized Medicine at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Majumder AAS; National Institute of Cardiovascular Diseases, Sher-e-Bangla Nagar, Dhaka, Bangladesh., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., McCarthy MI; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK.; Genentech, South San Francisco, San Francisco, CA, USA., Melander O; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Murray AD; The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK., Nordestgaard BG; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Orho-Melander M; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden., Packard CJ; University of Glasgow, Glasgow, UK., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK., Palmas W; Department of Medicine, Columbia University Medical Center, New York, NY, USA., Polasek O; Department of Public Health, University of Split School of Medicine, Split, Croatia., Porteous DJ; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, UK., Prentice AM; MRC Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, Gambia.; MRC International Nutrition Group at London School of Hygiene and Tropical Medicine, Keppel St, London, UK., Province MA; Division of Statistical Genomics, Department of Genetics and Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA., Relton CL; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Rice K; Department of Biostatistics, University of Washington, Seattle, WA, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Rolandsson O; Department of Public Health & Clinical Medicine, Umeå University, Umeå, Sweden., Rosendaal FR; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Rotter JI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Scotland, UK., Salomaa V; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Centre, Leicester, UK., Sattar N; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, UK., Sheu WH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan.; Institute of Medical Technology, National Chung-Hsing University, Taichung, Taiwan., Smith BH; Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Soranzo N; National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK.; Department of Human Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Research Centre, University of Edinburgh, Edinburgh, UK., Sebert S; Center for Life-Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland., Taylor KD; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Lakka TA; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio, Finland., Timpson NJ; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Tobin MD; National Institute for Health Research Leicester Biomedical Research Centre, Leicester, UK.; Department of Health Sciences, University of Leicester, Leicester, UK., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands.; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, the Netherlands., van der Meer P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands., Ramachandran VS; Boston University and National Heart, Lung and Blood Institute Framingham Heart Study, Framingham, MA, USA.; Boston University Schools of Medicine and Public Health, Boston, MA, USA., Verweij N; University Medical Center Groningen, Groningen, the Netherlands., Virtamo J; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland., Völker U; Interfaculty Institute for Genetics and Functional Genomics, University Medicine and University of Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Zeggini E; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Institute of Translational Genomics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; TUM School of Medicine, Technical University of Munich and Klinikum Rechts der Isar, Munich, Germany., Charchar FJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; Health Innovation and Transformation Center, Federation University Australia, Ballarat, Victoria, Australia.; Department of Physiology, University of Melbourne, Melbourne, Victoria, Australia., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Tomaszewski M; Division of Cardiovascular Sciences, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK.; Division of Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK.; National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK., Caulfield MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Danesh J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK.; National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK.; Department of Human Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Edwards TL; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Holm H; deCODE genetics/Amgen, Inc, Reykjavik, Iceland., Hung AM; VA Tennessee Valley Healthcare System, Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt Center for Kidney Disease, Vanderbilt University Medical Center, Nashville, TN, USA., Lindgren CM; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; The Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Liu C; Boston University School of Public Health, Boston, MA, USA., Manning AK; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Clinical and Translational Epidemiology Unit, Mongan Institute, Massachusetts General Hospital, Boston, MA, USA., Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, University of Manchester, Manchester, UK., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., O'Donnell CJ; VA Boston Healthcare, Section of Cardiology and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Saleheen D; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Non-Communicable Diseases, Karachi, Pakistan., Stefansson K; deCODE genetics/Amgen, Inc, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Levy D; Boston University and National Heart, Lung and Blood Institute Framingham Heart Study, Framingham, MA, USA.; Population Sciences, Branch, National Heart, Lung, and Blood Institute, National Institute of Health, Bethesda, MD, USA., Newton-Cheh C; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Munroe PB; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. p.b.munroe@qmul.ac.uk.; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK. p.b.munroe@qmul.ac.uk., Howson JMM; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. JMMHowson@gmail.com.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK. JMMHowson@gmail.com.; Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK. JMMHowson@gmail.com.; Novo Nordisk Research Centre Oxford, Novo Nordisk Ltd, Oxford, UK. JMMHowson@gmail.com.
Publikováno v:
Nature genetics [Nat Genet] 2020 Dec; Vol. 52 (12), pp. 1314-1332. Date of Electronic Publication: 2020 Nov 23.
Autor:
Sung YJ; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA., de Las Fuentes L; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.; Cardiovascular Division, Department of Medicine, Washington University, St. Louis, MO, USA., Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Chasman DI; Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Kraja AT; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Ntalla I; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Warren HR; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, London, UK., Guo X; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Schwander K; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA., Manning AK; Center for Human Genetics Research, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Brown MR; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Aschard H; Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.; Centre de Bioinformatique, Biostatistique et Biologie Intégrative (C3BI), Institut Pasteur, Paris, France., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Franceschini N; Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC, USA., Lu Y; Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, New York, NY, USA., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Sim X; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore., Vojinovic D; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Marten J; Medical Research Council Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Musani SK; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Kilpeläinen TO; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Environmental Medicine and Public Health, The Icahn School of Medicine at Mount Sinai, New York, NY, USA., Richard MA; Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Aslibekyan S; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA., Bartz TM; Cardiovascular Health Research Unit, Biostatistics and Medicine, University of Washington, Seattle, WA, USA., Dorajoo R; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore., Li C; Epidemiology and Biostatistics, University of Georgia at Athens College of Public Health, Athens, GA, USA., Liu Y; Public Health Sciences, Epidemiology and Prevention, Wake Forest University Health Sciences, Winston-Salem, NC, USA., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA., Smith AV; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Tajuddin SM; Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Tayo BO; Department of Public Health Sciences, Loyola University Chicago, Maywood, IL, USA., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Zhou Y; Biostatistics, Boston University School of Public Health, Boston, MA, USA., Matoba N; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Sofer T; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA., Alver M; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Amini M; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen RB, The Netherlands., Boissel M; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France., Chai JF; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore., Chen X; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, Sweden., Divers J; Biostatistical Sciences, Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Gandin I; Department of Medical Sciences, University of Trieste, Trieste, Italy., Gao C; Molecular Genetics and Genomics Program, Wake Forest School of Medicine, Winston-Salem, NC, USA., Giulianini F; Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Goel A; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, Oxfordshire, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, UK., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.; Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK., Hartwig FP; Postgraduate Programme in Epidemiology, Federal University of Pelotas, Pelotas, RS, Brazil.; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK., He M; Lab Genetics and Molecular Cardiology, Cardiology, Heart Institute, University of Sao Paulo, Sao Paulo, CA, USA., Horimoto ARVR; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Hsu FC; Biostatistical Sciences, Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Jackson AU; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA., Kammerer CM; Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., Kasturiratne A; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Komulainen P; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Kühnel B; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Leander K; Medical Research, Taichung Veterans General Hospital, Department of Social Work, Tunghai University, Taichung, Taiwan., Lee WJ; Ophthalmology, Taichung Veterans General Hospital, Taichung, Taiwan., Lin KH; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Luan J; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland., Lyytikäinen LP; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, Jamaica., McKenzie CA; School of Public Health, Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongi Medical College, Huazhong University of Science and Technology, Wuhan, China., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Noordam R; Internal Medicine, Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands., Scott RA; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland., Sheu WHH; Endocrinology and Metabolism, Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Yang-ming University, Taipei, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan.; Institute of Medical Technology, National Chung-Hsing University, Taichung, Taiwan., Stančáková A; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen RB, The Netherlands., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Malmö, Sweden., Waken RJ; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA., Wang H; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA., Wang Y; Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA., Ware EB; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Ernst Moritz Arndt University Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Health), Partner Site Greifswald, Greifswald, Germany., Wen W; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA., Yanek LR; General Internal Medicine, GeneSTAR Research Program, Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Zhang W; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK., Zhao JH; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland., Afaq S; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Alfred T; Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, New York, NY, USA., Amin N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Arking DE; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Aung T; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Barr RG; Departments of Medicine and Epidemiology, Columbia University Medical Center, New York, NY, USA., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Bottinger EP; Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, New York, NY, USA., Braund PS; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Brody JA; Cardiovascular Health Research Unit, Medicine, University of Washington, Seattle, WA, USA., Broeckel U; Section of Genomic Pediatrics, Department of Pediatrics, Medicine and Physiology, Medical College of Wisconsin, Milwaukee, WI, USA., Cade B; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA., Campbell A; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK., Canouil M; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France., Chakravarti A; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Cocca M; Department of Medical Sciences, University of Trieste, Trieste, Italy., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Connell JM; Ninewells Hospital & Medical School, University of Dundee, Dundee, Scotland, UK., de Mutsert R; Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., de Silva HJ; Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., Dörr M; DZHK (German Centre for Cardiovascular Health), Partner Site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Duan Q; Department of Genetics, University of North Carolina, Chapel Hill, USA., Eaton CB; Department of Family Medicine and Epidemiology, Alpert Medical School of Brown University, Providence, RI, USA., Ehret G; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Cardiology, Department of Specialties of Medicine, Geneva University Hospital, Geneva, Switzerland., Evangelou E; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Forouhi NG; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland., Franco OH; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Friedlander Y; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, Israel., Gao H; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Gigante B; Medical Research, Taichung Veterans General Hospital, Department of Social Work, Tunghai University, Taichung, Taiwan., Gu CC; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA., Gupta P; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Hagenaars SP; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.; Psychology, The University of Edinburgh, Edinburgh, UK., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., He J; Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.; Medicine, Tulane University School of Medicine, New Orleans, LA, USA., Heikkinen S; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland., Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore., Hofman A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Howard BV; MedStar Health Research Institute, Hyattsville, MD, USA.; Center for Clinical and Translational Sciences and Department of Medicine, Georgetown-Howard Universities, Washington, DC, USA., Hunt SC; Division of Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.; Department of Genetic Medicine, Weill Cornell Medicine, Doha, Qatar., Irvin MR; Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA., Jia Y; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Katsuya T; Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Japan., Kaufman J; Epidemiology, Occupational and Environmental Medicine Program, University of Washington, Seattle, WA, USA., Kerrison ND; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland., Khor CC; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.; Department of Biochemistry, National University of Singapore, Singapore, Singapore., Koh WP; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore.; Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore., Koistinen HA; Department of Public Health Solutions, National Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine and Abdominal Center: Endocrinology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Biomedicum 2U, Helsinki Finland., Kooperberg CB; Fred Hutchinson Cancer Research Center, University of Washington School of Public Health, Seattle, WA, USA., Krieger JE; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Kubo M; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Kutalik Z; Institute of Social Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., Lakka TA; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Langefeld CD; Biostatistical Sciences, Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Langenberg C; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Lee JH; Sergievsky Center, College of Physicians and Surgeons, Columbia University Mailman School of Public Health, New York, NY, USA., Lehne B; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Levy D; NHLBI Framingham Heart Study, Framingham, MA, USA.; The Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Lewis CE; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Li Y; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA., Lim SH; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Liu CT; Biostatistics, Boston University School of Public Health, Boston, MA, USA., Liu J; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore., Liu J; WHI CCC, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Liu Y; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Loh M; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore., Lohman KK; Biostatistical Sciences, Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Louie T; Department of Biostatistics, University of Washington, Seattle, WA, USA., Mägi R; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Matsuda K; Laboratory for Clinical Genome Sequencing, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Minato-ku, Japan., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany., Metspalu A; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Milani L; Cardiovascular Division, Department of Medicine, Washington University, St. Louis, MO, USA., Momozawa Y; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Mosley TH Jr; Geriatrics, Medicine, University of Mississippi, Jackson, MS, USA., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA., Nasri U; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., O'Connell JR; Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.; Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Ogunniyi A; Department of Medicine, University of Ibadan, Ibadan, Nigeria., Palmas WR; Internal Medicine, Columbia University, New York, NY, USA., Palmer ND; Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Pankow JS; Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN, USA., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, Sweden., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Neuherberg, Germany., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Polasek O; Department of Public Health, Department of Medicine, University of Split, Split, Croatia.; Psychiatric Hospital 'Sveti Ivan', Zagreb, Croatia.; Gen-info Ltd, Zagreb, Croatia., Porteous D; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Malmö, Sweden.; Department of Biobank Research, Umeå University, Umeå, Västerbotten, Sweden., Rice TK; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA., Ridker PM; Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Robino A; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Trieste, Italy., Robinson JG; Department of Epidemiology and Medicine, University of Iowa, Iowa City, IA, USA., Rose LM; Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Sabanayagam C; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore., Salako BL; Department of Medicine, University of Ibadan, Ibadan, Nigeria., Sandow K; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Schmidt CO; DZHK (German Centre for Cardiovascular Health), Partner Site Greifswald, Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Schreiner PJ; Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN, USA., Scott WR; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Sever P; International Centre for Circulatory Health, Imperial College London, London, UK., Sims M; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Sitlani CM; Cardiovascular Health Research Unit, Medicine, University of Washington, Seattle, WA, USA., Smith BH; Division of Population Health Sciences, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen RB, The Netherlands., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, The University of Edinburgh, Edinburgh, UK., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Genetic Epidemiology, IBE, Faculty of Medicine, LMU, Munich, Germany., Tang H; Department of Genetics, Stanford University, Stanford, CA, USA., Taylor KD; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Teo YY; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.; Life Sciences Institute, National University of Singapore, Singapore, Singapore.; NUS Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore, Singapore.; Department of Statistics and Applied Probability, National University of Singapore, Singapore, Singapore., Tham YC; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Uitterlinden AG; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Wang L; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Wang YX; Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Ophthalmology and Visual Science Key Lab, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Wei WB; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Wilson G; Jackson Heart Study, School of Public Health, Jackson State University, Jackson, MS, USA., Wojczynski MK; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Xiang YB; State Key Laboratory of Oncogene and Related Genes & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P.R. China., Yao J; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Yuan JM; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.; Division of Cancer Control and Population Sciences, UPMC Hillman Cancer, University of Pittsburgh, Pittsburgh, PA, USA., Zonderman AB; Behavioral Epidemiology Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Becker DM; General Internal Medicine, GeneSTAR Research Program, Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Bowden DW; Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Chambers JC; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK., Chen YI; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., de Faire U; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.; Psychology, The University of Edinburgh, Edinburgh, UK., Esko T; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Boston, MA, USA., Farrall M; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, Oxfordshire, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, UK., Forrester T; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, Jamaica., Freedman BI; Nephrology, Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA., Froguel P; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France.; Department of Genomics of Common Disease, Imperial College London, London, UK., Gasparini P; Department of Medical Sciences, University of Trieste, Trieste, Italy.; Department of Genetic Medicine, Weill Cornell Medicine, Doha, Qatar., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany., Horta BL; Postgraduate Programme in Epidemiology, Federal University of Pelotas, Pelotas, RS, Brazil., Hung YJ; Endocrinology and Metabolism, Tri-Service General Hospital, National Defense Medical Center, Taipei City, Taipei, Taiwan., Jonas JB; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.; Department of Ophthalmology, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany., Kato N; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan., Kooner JS; Department of Cardiology, Ealing Hospital, Middlesex, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Liang KW; School of Medicine, National Yang-ming University, Taipei, Taiwan.; Cardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan.; Department of Medicine, China Medical University, Taichung, Taiwan., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, Sweden., Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen RB, The Netherlands., Pereira AC; Lab Genetics and Molecular Cardiology, Cardiology, Heart Institute, University of Sao Paulo, Sao Paulo, CA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA., Perls T; Geriatrics Section, Boston University Medical Center, Boston, MA, USA., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Redline S; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA., Rettig R; DZHK (German Centre for Cardiovascular Health), Partner Site Greifswald, Greifswald, Germany.; Institute of Physiology, University of Medicine Greifswald, Greifswald, Germany., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Scott J; National Heart and Lung Institute, Imperial College London, London, UK., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA., van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen RB, The Netherlands., Wagenknecht LE; Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Watkins H; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, Oxfordshire, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, UK., Wickremasinghe AR; Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., Wu T; School of Public Health, Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongi Medical College, Huazhong University of Science and Technology, Wuhan, China., Kamatani Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Laurie CC; Department of Biostatistics, University of Washington, Seattle, WA, USA., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA., Cooper RS; Department of Public Health Sciences, Loyola University Chicago, Maywood, IL, USA., Evans MK; Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Hixson J; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Kritchevsky SB; Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA., Psaty BM; Cardiovascular Health Research Unit, Epidemiology, Medicine and Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., van Dam RM; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Arnett DK; Dean's Office, University of Kentucky College of Public Health, Lexington, KY, USA., Mook-Kanamori DO; Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.; Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands., Fornage M; Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Fox ER; Cardiology, Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Hayward C; Medical Research Council Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., van Duijn CM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Tai ES; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore.; Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Wong TY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Loos RJF; Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, New York, NY, USA.; Icahn School of Medicine at Mount Sinai, The Mindich Child Health and Development Institute, New York, NY, USA., Reiner AP; Fred Hutchinson Cancer Research Center, University of Washington School of Public Health, Seattle, WA, USA., Rotimi CN; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Bierut LJ; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA., Zhu X; Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA., Cupples LA; Biostatistics, Boston University School of Public Health, Boston, MA, USA., Province MA; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Rotter JI; Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Malmö, Sweden.; Harvard T. H. Chan School of Public Health, Department of Nutrition, Harvard University, Boston, MA, USA.; Department of Public Health & Clinical Medicine, Umeå University, Umeå, Västerbotten, Sweden., Rice K; Department of Biostatistics, University of Washington, Seattle, WA, USA., Elliott P; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Caulfield MJ; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, London, UK., Gauderman WJ; Biostatistics, Preventive Medicine, University of Southern California, Los Angeles, CA, USA., Munroe PB; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, London, UK., Rao DC; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Publikováno v:
Human molecular genetics [Hum Mol Genet] 2019 Aug 01; Vol. 28 (15), pp. 2615-2633.
Autor:
Altschul DM; From the Department of Psychology (D.M.A., C.W., I.J.D.), University of Edinburgh, United Kingdom.; Centre for Cognitive Ageing and Cognitive Epidemiology (D.M.A., C.W., C.R.G., I.J.D.), University of Edinburgh, United Kingdom., Wraw C; From the Department of Psychology (D.M.A., C.W., I.J.D.), University of Edinburgh, United Kingdom.; Centre for Cognitive Ageing and Cognitive Epidemiology (D.M.A., C.W., C.R.G., I.J.D.), University of Edinburgh, United Kingdom., Der G; MRC/CSO Social and Public Health Sciences Unit, University of Glasgow, United Kingdom (G.D.)., Gale CR; Centre for Cognitive Ageing and Cognitive Epidemiology (D.M.A., C.W., C.R.G., I.J.D.), University of Edinburgh, United Kingdom.; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, United Kingdom (C.R.G.)., Deary IJ; From the Department of Psychology (D.M.A., C.W., I.J.D.), University of Edinburgh, United Kingdom.; Centre for Cognitive Ageing and Cognitive Epidemiology (D.M.A., C.W., C.R.G., I.J.D.), University of Edinburgh, United Kingdom.
Publikováno v:
Hypertension (Dallas, Tex. : 1979) [Hypertension] 2019 Apr; Vol. 73 (4), pp. 812-819.
Autor:
Marini S; Center for Genomic Medicine, Massachusetts General Hospital, Boston., Crawford K; Center for Genomic Medicine, Massachusetts General Hospital, Boston., Morotti A; Stroke Unit, IRCCS Mondino Foundation, Pavia, Italy., Lee MJ; Department of Neurology, Massachusetts General Hospital, Boston., Pezzini A; Department of Clinical and Experimental Sciences, Neurology Clinic, University of Brescia, Brescia, Italy., Moomaw CJ; Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio., Flaherty ML; Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio., Montaner J; Neurovascular Research Laboratory and Neurovascular Unit, Institut de Recerca, Hospital Vall d'Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain.; Institute de Biomedicine of Seville, IBiS/Hospital Universitario Virgen del Rocío/CSIC/University of Seville, Seville, Spain.; Department of Neurology, Hospital Universitario Virgen Macarena, Seville, Spain., Roquer J; Department of Neurology, Neurovascular Research Unit, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain., Jimenez-Conde J; Department of Neurology, Neurovascular Research Unit, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain., Giralt-Steinhauer E; Department of Neurology, Neurovascular Research Unit, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain., Elosua R; Department of Neurology, Neurovascular Research Unit, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain., Cuadrado-Godia E; Department of Neurology, Neurovascular Research Unit, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain., Soriano-Tarraga C; Department of Neurology, Neurovascular Research Unit, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain., Slowik A; Department of Neurology, Jagiellonian University Medical College, Krakow, Poland., Jagiella JM; Department of Neurology, Jagiellonian University Medical College, Krakow, Poland., Pera J; Department of Neurology, Jagiellonian University Medical College, Krakow, Poland., Urbanik A; Department of Neurology, Jagiellonian University Medical College, Krakow, Poland., Pichler A; Department of Neurology, Jagiellonian University Medical College, Krakow, Poland., Hansen BM; Department of Clinical Sciences Lund, Neurology, Lund University, Lund, Sweden.; Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden., McCauley JL; John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami., Tirschwell DL; Stroke Center, Harborview Medical Center, University of Washington, Seattle., Selim M; Department of Neurology, Stroke Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts., Brown DL; Cardiovascular Center, University of Michigan, Ann Arbor., Silliman SL; Department of Neurology, University of Florida College of Medicine, Jacksonville., Worrall BB; Department of Neurology and Public Health Sciences, University of Virginia Health System, Charlottesville., Meschia JF; Department of Neurology, Mayo Clinic, Jacksonville, Florida., Kidwell CS; Department of Neurology, University of Arizona, Tucson., Testai FD; Department of Neurology and Rehabilitation, University of Illinois College of Medicine, Chicago., Kittner SJ; Department of Neurology, Baltimore Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore., Schmidt H; Department of Neurology, Medical University of Graz, Graz, Austria., Enzinger C; Department of Neurology, Medical University of Graz, Graz, Austria., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, United Kingdom., Rannikmae K; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom., Samarasekera N; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom., Al-Shahi Salman R; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom., Sudlow CL; Centre for Medical Informatics, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom., Klijn CJM; Department of Neurology, Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, the Netherlands.; Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands., van Nieuwenhuizen KM; Department of Neurology, Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, the Netherlands.; Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands., Fernandez-Cadenas I; Neurovascular Research Laboratory and Neurovascular Unit, Institut de Recerca, Hospital Vall d'Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain.; Stroke Pharmacogenomics and Genetics, Sant Pau Institute of Research, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Delgado P; Neurovascular Research Laboratory and Neurovascular Unit, Institut de Recerca, Hospital Vall d'Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain., Norrving B; Department of Clinical Sciences Lund, Neurology, Lund University, Lund, Sweden.; Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden., Lindgren A; Department of Clinical Sciences Lund, Neurology, Lund University, Lund, Sweden.; Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden., Goldstein JN; Department of Neurology, Massachusetts General Hospital, Boston., Viswanathan A; Department of Neurology, Massachusetts General Hospital, Boston., Greenberg SM; Department of Neurology, Massachusetts General Hospital, Boston., Falcone GJ; Division of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale University School of Medicine, New Haven, Connecticut.; Center for Neuroepidemiology and Clinical Neurological Research, Yale School of Medicine, Yale University, New Haven, Connecticut., Biffi A; Division of Behavioral Neurology, Massachusetts General Hospital, Boston., Langefeld CD; Center for Public Health Genomics and Department of Biostatistical Sciences, Wake Forest University, Winston-Salem, North Carolina., Woo D; Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio., Rosand J; Center for Genomic Medicine, Massachusetts General Hospital, Boston.; Department of Neurology, Massachusetts General Hospital, Boston.; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts., Anderson CD; Center for Genomic Medicine, Massachusetts General Hospital, Boston.; Department of Neurology, Massachusetts General Hospital, Boston.; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts.
Publikováno v:
JAMA neurology [JAMA Neurol] 2019 Apr 01; Vol. 76 (4), pp. 480-491.
Autor:
Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Kraja AT; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Chasman DI; Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.; Harvard Medical School, Boston, Massachusetts, United States of America., Sung YJ; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Ntalla I; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom., Guo X; Genomic Outcomes, Pediatrics, Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, United States of America., Franceschini N; Epidemiology, University of North Carolina Gilling School of Global Public Health, Chapel Hill, North Carolina, United States of America., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Sim X; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore., Vojinovic D; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Marten J; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Musani SK; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, United States of America., Li C; Epidemiology and Biostatistics, University of Georgia at Athens College of Public Health, Athens, Georgia, United States of America., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Brown MR; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America., Schwander K; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Richard MA; Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America., Noordam R; Internal Medicine, Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands., Aschard H; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America.; Centre de Bioinformatique, Biostatistique et Biologie Intégrative (C3BI), Institut Pasteur, Paris, France., Bartz TM; Cardiovascular Health Research Unit, Biostatistics and Medicine, University of Washington, Seattle, Washington, United States of America., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, United States of America., Dorajoo R; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore., Fisher V; Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America., Hartwig FP; Postgraduate Programme in Epidemiology, Federal University of Pelotas, Pelotas, RS, Brazil.; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom., Horimoto ARVR; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, SP, Brazil., Lohman KK; Biostatistical Sciences, Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Manning AK; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America., Smith AV; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Tajuddin SM; Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America., Wojczynski MK; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Alver M; Estonian Genome Center, University of Tartu, Tartu, Estonia., Boissel M; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France., Cai Q; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America., Campbell A; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Chai JF; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore., Chen X; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, Sweden., Divers J; Biostatistical Sciences, Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Gao C; Molecular Genetics and Genomics Program, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Goel A; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, Oxfordshire, United Kingdom.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, United Kingdom., Hagemeijer Y; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, United Kingdom.; Medical Genetics Section, Centre for Genomic and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, United Kingdom., He M; Department of Occupational and Environmental Health, State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Hsu FC; Biostatistical Sciences, Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; University of Tampere, Tampere, Finland., Kasturiratne A; Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., Komulainen P; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Kühnel B; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Laguzzi F; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Luan J; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Matoba N; Laboratory for Statistical Analysis, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom., Riaz M; Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom., Rueedi R; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Instititute of Bioinformatics, Lausanne, Switzerland., Robino A; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Trieste, Italy., Said MA; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Scott RA; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Sofer T; Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America.; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, United States of America., Stančáková A; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan., Tayo BO; Department of Public Health Sciences, Loyola University Chicago, Maywood, Illinois, United States of America., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Malmö, Sweden., Vitart V; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Wang Y; Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, United States of America., Ware EB; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, United States of America., Warren HR; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.; NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, London, United Kingdom., Weiss S; Interfaculty Institute for Genetics and Functional genomics, University Medicine Ernst Moritz Arndt University Greifsald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Wen W; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America., Yanek LR; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom.; Department of Cardiology, Ealing Hospital, Middlesex, United Kingdom., Zhao JH; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Afaq S; Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom., Amin N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Amini M; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Arking DE; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America., Aung T; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Boerwinkle E; Department of Epidemiology, Human Genetics, and Environmental Sciences, The University of Texas School of Public Health, Houston, Texas, United States of America.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America., Borecki I; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Broeckel U; Section of Genomic Pediatrics, Department of Pediatrics, Medicine and Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America., Brown M; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.; NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, London, United Kingdom., Brumat M; Department of Medical Sciences, University of Trieste, Trieste, Italy., Burke GL; Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Canouil M; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France., Chakravarti A; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America., Charumathi S; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore., Ida Chen YD; Genomic Outcomes, Pediatrics, Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, United States of America., Connell JM; Ninewells Hospital & Medical School, University of Dundee, Dundee, Scotland, United Kingdom., Correa A; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, United States of America., de Las Fuentes L; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America.; Cardiovascular Division, Department of Medicine, Washington University, St. Louis, Missouri, United States of America., de Mutsert R; Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., de Silva HJ; Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., Deng X; Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America., Ding J; Center on Diabetes, Obesity, and Metabolism, Gerontology and Geriatric Medicine, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America., Duan Q; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America., Eaton CB; Department of Family Medicine and Epidemiology, Alpert Medical School of Brown University, Providence, Rhode Island, United States of America., Ehret G; Cardiology, Geneva University Hospital, Geneva, Switzerland., Eppinga RN; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Evangelou E; Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, United States of America., Felix SB; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Forouhi NG; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Forrester T; The Caribbean Institute for Health Research (CAIHR), University of the West Indies, Mona, Jamaica., Franco OH; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Friedlander Y; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, Israel., Gandin I; Department of Medical Sciences, University of Trieste, Trieste, Italy., Gao H; Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom., Ghanbari M; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Gigante B; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Gu CC; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Gu D; Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Hagenaars SP; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, United Kingdom.; Psychology, The University of Edinburgh, Edinburgh, United Kingdom., Hallmans G; Department of Public Health and Clinical Medicine, Nutritional Research, Umeå University, Umeå, Västerbotten, Sweden., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America., He J; Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, United States of America.; Medicine, Tulane University School of Medicine, New Orleans, Louisiana, United States of America., Heikkinen S; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland., Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore., Hirata M; Laboratory of Genome Technology, Human Genome Center, Institute of Medical Science, The University of Tokyo, Minato-ku, Japan., Howard BV; MedStar Health Research Institute, Hyattsville, Maryland, United States of America.; Center for Clinical and Translational Sciences and Department of Medicine, Georgetown-Howard Universities, Washington, DC, United States of America., Ikram MA; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands., John U; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute of Social Medicine and Prevention, University Medicine Greifswald, Greifswald, Germany., Katsuya T; Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Japan., Khor CC; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.; Department of Biochemistry, National University of Singapore, Singapore, Singapore., Kilpeläinen TO; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Environmental Medicine and Public Health, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America., Koh WP; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Krieger JE; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, SP, Brazil., Kritchevsky SB; Sticht Center for Healthy Aging and Alzheimer's Prevention, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Kubo M; Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., Lakka TA; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Langefeld CD; Biostatistical Sciences, Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Langenberg C; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America., Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom., Lewis CE; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States of America., Li Y; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Lin S; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Liu J; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore., Liu J; WHI CCC, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America., Loh M; Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom.; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore., Louie T; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., McKenzie CA; The Caribbean Institute for Health Research (CAIHR), University of the West Indies, Mona, Jamaica., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia., Milaneschi Y; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, The Netherlands., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America., Momozawa Y; Laboratory for Genotyping Development, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan., Nalls MA; Data Tecnica International, Glen Echo, Maryland, United States of America.; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, United States of America., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom., Sotoodehnia N; Cardiovascular Health Research Unit, Division of Cardiology, University of Washington, Seattle, Washington, United States of America., Norris JM; Department of Epidemiology, Colorado School of Public Health, Aurora, Colorado, United States of America., O'Connell JR; Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.; Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America., Palmer ND; Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Perls T; Geriatrics Section, Boston University Medical Center, Boston, Massachusetts, United States of America., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, Sweden., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Neuherberg, Germany., Peyser PA; 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Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Schreiner PJ; Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, United States of America., Schupf N; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, New York, United States of America., Scott WR; Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom.; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Sever PS; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Shi Y; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Sidney S; Division of Research, Kaiser Permanente of Northern California, Oakland, California, United States of America., Sims M; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, United States of America., Sitlani CM; Cardiovascular Health Research Unit, Medicine, University of Washington, Seattle, Washington, United States of America., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, United States of America.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, United States of America., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, United Kingdom.; Alzheimer Scotland Dementia Research Centre, The University of Edinburgh, Edinburgh, United Kingdom., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU, Munich, Germany., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America., Tan NYQ; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Tang H; Department of Genetics, Stanford University, Stanford, California, United States of America., Taylor KD; Genomic Outcomes, Pediatrics, Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, United States of America., Teo YY; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.; Life Sciences Institute, National University of Singapore, Singapore, Singapore.; NUS Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore, Singapore.; Department of Statistics and Applied Probability, National University of Singapore, Singapore, Singapore., Tham YC; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Turner ST; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States of America., Uitterlinden AG; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Vollenweider P; Service of Internal Medicine, Department of Internal Medicine, University Hospital, Lausanne, Switzerland., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Wang L; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Wang YX; Beijing Institute of Ophthalmology, Beijing Ophthalmology and Visual Science Key Lab, Beijing Tongren Eye Center, Capital Medical University, Beijing, China.; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Wei WB; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Williams C; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Yao J; Genomic Outcomes, Pediatrics, Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, United States of America., Yu C; Department of Occupational and Environmental Health, State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Yuan JM; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Division of Cancer Control and Population Sciences, UPMC Hillman Cancer, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, United States of America., Zonderman AB; Behavioral Epidemiology Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America., Becker DM; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America., Bowden DW; Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom.; Department of Cardiology, Ealing Hospital, Middlesex, United Kingdom.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Imperial College Healthcare NHS Trust, London, United Kingdom.; MRC-PHE Centre for Environment and Health, Department of Epidemiology & Biostatistics, School of Public Health, Imperial College London, London, United Kingdom., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, United Kingdom.; Psychology, The University of Edinburgh, Edinburgh, United Kingdom., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Boston, Massachusetts, United States of America., Farrall M; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, Oxfordshire, United Kingdom.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, United Kingdom., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Malmö, Sweden.; 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Department of Ophthalmology, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany, Germany., Kamatani Y; Laboratory for Statistical Analysis, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan., Kato N; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan., Kooner JS; Department of Cardiology, Ealing Hospital, Middlesex, United Kingdom.; National Heart and Lung Institute, Imperial College London, London, United Kingdom.; Imperial College Healthcare NHS Trust, London, United Kingdom.; MRC-PHE Centre for Environment and Health, Department of Epidemiology & Biostatistics, School of Public Health, Imperial College London, London, United Kingdom., Kutalik Z; Swiss Instititute of Bioinformatics, Lausanne, Switzerland.; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., Laurie CC; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America., Leander K; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Study LC; Lifelines Cohort, Groningen, The Netherlands., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, Sweden., Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Penninx BWJH; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, The Netherlands., Polasek O; Department of Public Health, Department of Medicine, University of Split, Split, Croatia.; Psychiatric Hospital 'Sveti Ivan', Zagreb, Croatia.; Gen-info Ltd, Zagreb, Croatia., Porteous DJ; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom., Scott J; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America., van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Wagenknecht LE; Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Watkins H; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, Oxfordshire, United Kingdom.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, United Kingdom., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, United States of America., Wickremasinghe AR; Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., Wu T; Department of Occupational and Environmental Health, State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America., Christensen K; The Danish Aging Research Center, Institute of Public Health, University of Southern Denmark, Odense, Denmark., Evans MK; Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Horta BL; Postgraduate Programme in Epidemiology, Federal University of Pelotas, Pelotas, RS, Brazil., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, United States of America., Liu Y; Public Health Sciences, Epidemiology and Prevention, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America., Pereira AC; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, SP, Brazil., Psaty BM; Cardiovascular Health Research Unit, Epidemiology, Medicine and Health Services, University of Washington, Seattle, Washington, United States of America.; Kaiser Permanente Washington, Health Research Institute, Seattle, Washington, United States of America., Ridker PM; Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.; Harvard Medical School, Boston, Massachusetts, United States of America., van Dam RM; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Gauderman WJ; Biostatistics, Preventive Medicine, University of Southern California, Los Angeles, California, United States of America., Zhu X; Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, United States of America., Mook-Kanamori DO; Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.; Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands., Fornage M; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.; Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America., Rotimi CN; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Cupples LA; Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.; The Framingham Heart Study, Framingham, Massachusetts, United States of America., Kelly TN; Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, United States of America., Fox ER; Cardiology, Medicine, University of Mississippi Medical Center, Jackson, Mississippi, United States of America., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom., van Duijn CM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Tai ES; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Wong TY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Kooperberg C; Fred Hutchinson Cancer Research Center, University of Washington School of Public Health, Seattle, Washington, United States of America., Palmas W; Medicine, Columbia University Medical Center, New York, New York, United States of America., Rice K; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America., Elliott P; MRC-PHE Centre for Environment and Health, Department of Epidemiology & Biostatistics, School of Public Health, Imperial College London, London, United Kingdom., Caulfield MJ; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.; NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, London, United Kingdom., Munroe PB; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.; NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, London, United Kingdom., Rao DC; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Province MA; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America., Levy D; The Framingham Heart Study, Framingham, Massachusetts, United States of America.; The Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Publikováno v:
PloS one [PLoS One] 2018 Jun 18; Vol. 13 (6), pp. e0198166. Date of Electronic Publication: 2018 Jun 18 (Print Publication: 2018).
Autor:
Lyall DM; Public Health, Institute of Health and Wellbeing, 1 Lilybank Gardens, University of Glasgow, Glasgow G11 5HE, UK., Celis-Morales CA; BHF Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8TA, UK., Anderson J; Public Health, Institute of Health and Wellbeing, 1 Lilybank Gardens, University of Glasgow, Glasgow G11 5HE, UK., Gill JM; BHF Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8TA, UK., Mackay DF; Public Health, Institute of Health and Wellbeing, 1 Lilybank Gardens, University of Glasgow, Glasgow G11 5HE, UK., McIntosh AM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh EH8 9JZ, UK., Smith DJ; Public Health, Institute of Health and Wellbeing, 1 Lilybank Gardens, University of Glasgow, Glasgow G11 5HE, UK., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh EH8 9JZ, UK., Sattar N; BHF Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8TA, UK., Pell JP; Public Health, Institute of Health and Wellbeing, 1 Lilybank Gardens, University of Glasgow, Glasgow G11 5HE, UK.
Publikováno v:
European heart journal [Eur Heart J] 2017 Feb 21; Vol. 38 (8), pp. 577-583.