Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Elisabeth Singer"'
Autor:
Libo Yu-Taeger, Arianna Novati, Jonasz Jeremiasz Weber, Elisabeth Singer-Mikosch, Ann-Sophie Pabst, Fubo Cheng, Carsten Saft, Jennifer Koenig, Gisa Ellrichmann, Taneli Heikkinen, Mahmoud A. Pouladi, Olaf Riess, Huu Phuc Nguyen
Publikováno v:
Cells; Volume 11; Issue 23; Pages: 3779
Body weight (BW) loss and reduced body mass index (BMI) are the most common peripheral alterations in Huntington disease (HD) and have been found in HD mutation carriers and HD animal models before the manifestation of neurological symptoms. This sug
Olfactory bulb atrophy and caspase activation observed in the BACHD rat models of Huntington disease
Autor:
Huu P. Nguyen, Mélissa Laroche, Libo Yu-Taeger, Mélissa Lessard-Beaudoin, Olaf Riess, Elisabeth Singer, Rona K. Graham
Publikováno v:
Neurobiology of Disease, Vol 125, Iss, Pp 219-231 (2019)
Olfactory dysfunction is observed in several neurological disorders, including Huntington disease (HD), and correlates with global cognitive performance, depression and degeneration of olfactory regions in the brain. Despite clear evidence demonstrat
Autor:
Olaf Riess, Florent Beaufils, Doriano Fabbro, Nadine Rischert, Huu Phuc Nguyen, Matthias P. Wymann, Carolin Walter, Denise Rageot, Elisabeth Singer, Petra Hillmann
Publikováno v:
Neuropharmacology. 162
One of the pathological hallmarks of Huntington disease (HD) is accumulation of the disease-causing mutant huntingtin (mHTT), which leads to the disruption of a variety of cellular functions, ultimately resulting in cell death. Induction of autophagy
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 87:A93.2-A93
Background The pathogenesis of HD is not entirely understood, but it is clear that the expression of the disease-causing mutant huntingtin protein leads to the disruption of a variety of cellular functions, which ultimately results in cell death. A h