Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Zewen K. Tuong"'
Autor:
Mathieu Uzzan, Jerome C. Martin, Luka Mesin, Alexandra E. Livanos, Tomas Castro-Dopico, Ruiqi Huang, Francesca Petralia, Giuliana Magri, Shashi Kumar, Qing Zhao, Adam K. Rosenstein, Minami Tokuyama, Keshav Sharma, Ryan Ungaro, Roman Kosoy, Divya Jha, Jeremy Fischer, Harpriya Singh, Mary E. Keir, Nandhini Ramamoorthi, William E. O’Gorman, Benjamin L. Cohen, Adeeb Rahman, Francesca Cossarini, Akihiro Seki, Louise Leyre, Sonia Tejedor Vaquero, Sakteesh Gurunathan, Emilie K. Grasset, Bojan Losic, Marla Dubinsky, Alexander J. Greenstein, Zoe Gottlieb, Peter Legnani, James George, Haritz Irizar, Aleksandar Stojmirovic, Carrie Brodmerkel, Andrew Kasarkis, Bruce E. Sands, Glaucia Furtado, Sergio A. Lira, Zewen K. Tuong, Huaibin M. Ko, Andrea Cerutti, Charles O. Elson, Menna R. Clatworthy, Miriam Merad, Mayte Suárez-Fariñas, Carmen Argmann, Jason A. Hackney, Gabriel D. Victora, Gwendalyn J. Randolph, Ephraim Kenigsberg, Jean Frederic Colombel, Saurabh Mehandru
Publikováno v:
Nat Med
B cells, which are critical for intestinal homeostasis, remain understudied in ulcerative colitis (UC). In this study, we recruited three cohorts of patients with UC (primary cohort, n = 145; validation cohort 1, n = 664; and validation cohort 2, n =
Publikováno v:
Immunological Reviews. 305:111-136
There is an increasing appreciation that many innate and adaptive immune cell subsets permanently reside within non-lymphoid organs, playing a critical role in tissue homeostasis and defense. The best characterized are macrophages and tissue-resident
Autor:
Nathan Richoz, Zewen K. Tuong, Kevin W. Loudon, Eduardo Patiño-Martínez, John R. Ferdinand, Anaïs Portet, Kathleen R. Bashant, Emeline Thevenon, Francesca Rucci, Thomas Hoyler, Tobias Junt, Mariana J. Kaplan, Richard M. Siegel, Menna R. Clatworthy
Publikováno v:
JCI Insight
Lupus nephritis is a serious complication of systemic lupus erythematosus, mediated by IgG immune complex (IC) deposition in kidneys, with limited treatment options. Kidney macrophages are critical tissue sentinels that express IgG-binding Fcγ recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71bba4bf9ded085e161a968478275ee8
https://www.repository.cam.ac.uk/handle/1810/344196
https://www.repository.cam.ac.uk/handle/1810/344196
Autor:
Yikun Yao, Ping Du Jiang, Brittany N. Chao, Deniz Cagdas, Satoshi Kubo, Arasu Balasubramaniyam, Yu Zhang, Bella Shadur, Adeeb NaserEddin, Les R. Folio, Benjamin Schwarz, Eric Bohrnsen, Lixin Zheng, Matthew Lynberg, Simone Gottlieb, Michael A. Leney-Greene, Ann Y. Park, Ilhan Tezcan, Ali Akdogan, Rahsan Gocmen, Sevgen Onder, Avi Rosenberg, Elizabeth J. Soilleux, Errin Johnson, Peter K. Jackson, Janos Demeter, Samuel D. Chauvin, Florian Paul, Matthias Selbach, Haydar Bulut, Menna R. Clatworthy, Zewen K. Tuong, Hanlin Zhang, Benjamin J. Stewart, Catharine M. Bosio, Polina Stepensky, Simon Clare, Sundar Ganesan, John C. Pascall, Oliver Daumke, Geoffrey W. Butcher, Andrew J. McMichael, Anna Katharina Simon, Michael J. Lenardo
Inborn errors of immunity (IEIs) unveil regulatory pathways of human immunity. We describe a new IEI caused by mutations in the GTPase of the immune-associated protein 6 (GIMAP6) gene in patients with infections, lymphoproliferation, autoimmunity, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e875cafd6e83da3c9610e843fba1a87e
http://edoc.mdc-berlin.de/21629/1/21629oa.pdf
http://edoc.mdc-berlin.de/21629/1/21629oa.pdf
Autor:
Siok Min Teoh, Paula Kuo, Janin Chandra, Ian H. Frazer, Lynn Tolley, Chengzhong Yu, Zibin Chen, Abate Assefa Bashaw, James W. Wells, Meihua Yu, Yang Liu, Zewen K. Tuong
Publikováno v:
The Journal of Immunology. 206:987-998
Prophylactic human papillomavirus (HPV) vaccines are commercially available for prevention of infection with cancerogenic HPV genotypes but are not able to combat pre-existing HPV-associated disease. In this study, we designed a nanomaterial-based th
Autor:
Zewen K. Tuong, Kourosh Saeb-Parsy, Jack Martin, Menna R. Clatworthy, Akimichi Inaba, Rebeccah J. Mathews, Alexandra M. Riding
Publikováno v:
The Journal of Immunology Author Choice
Key Points AKI is a serious condition affecting one fifth of hospital patients. In AKI, B cells produce CCL7 and facilitate neutrophil and monocyte recruitment. CCL7 blockade in mice reduces myeloid cell infiltration and ameliorates AKI.
Acute k
Acute k
Autor:
Kathleen R Bashant, Rebeccah J. Mathews, Gemma D Banham, Mariana J. Kaplan, Arthur Kaser, Nathan Richoz, Zewen K. Tuong, Zaeem Cader, Chenzhi Jing, Randall S. Johnson, Kevin W. Loudon, Susan Fitzpatrick, Richard M. Siegel, Tomas Castro-Dopico, Michael P. Murphy, Menna R. Clatworthy, Laurence S C Lok, John R. Ferdinand
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance IgG antibodies are a key component of adaptive humoral immunity but can cause organ damage if they bind self-antigen, as occurs in the autoimmune disease systemic lupus erythematosus (SLE). Many of the proinflammatory effects of IgG are
Autor:
Samuel W. Lukowski, H. Peter Soyer, Ian H. Frazer, Erin McMeniman, Katharina Devitt, Zewen K. Tuong, Sarah J. Hanson
Publikováno v:
Virology. 537:14-19
Human Papillomavirus infection is highly prevalent worldwide. While most types of HPV cause benign warts, some high-risk types are known to cause cervical cancer, as well as cancer of the oral cavity and head and neck. Persistent cutaneous HPV infect
Autor:
Raymond J. Steptoe, Andrew W. Lewandowski, James W. Wells, H. Peter Soyer, Fiona Simpson, Graham R. Leggatt, Ian H. Frazer, Duncan Lambie, Miko Yamada, Zewen K. Tuong, Richard Lewandowski, Jazmina L. G. Cruz, Jennifer A. Bridge
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Actinic Keratosis (AK), Intraepidermal Carcinoma (IEC), and Squamous Cell Carcinoma (SCC) are generally considered to be advancing stages of the same disease spectrum. However, while AK often regress spontaneously, and IEC often regress in response t
Autor:
Tomas Castro-Dopico, Chenzhi Jing, Simon Clare, Thomas W. Dennison, Katherine Harcourt, John R. Ferdinand, Menna R. Clatworthy, Arthur Kaser, Laurence S C Lok, Zaeem Cader, Aaron M. Fleming, Benjamin J. Stewart, Anaïs Portet, Rebeccah J. Mathews, Zewen K. Tuong
Publikováno v:
Cell Reports
Summary Macrophages play a central role in intestinal immunity, but inappropriate macrophage activation is associated with inflammatory bowel disease (IBD). Here, we identify granulocyte-macrophage colony stimulating factor (GM-CSF) as a critical reg