Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yujeong Lee"'
Autor:
Yujeong Lee, Yoshiyuki Onishi, Lisa McPherson, Anna M. Kietrys, Marian Hebenbrock, Yong Woong Jun, Ishani Das, Shanthi Adimoolam, Debin Ji, Michael G. Mohsen, James M. Ford, Eric T. Kool
Publikováno v:
ACS Chemical Biology. 17:2074-2087
Impaired DNA repair activity has been shown to greatly increase rates of cancer clinically. It has been hypothesized that upregulating repair activity in susceptible individuals may be a useful strategy for inhibiting tumorigenesis. Here, we report t
Publikováno v:
Journal of Alzheimer's Disease. 77:1-14
Alzheimer’s disease (AD) is the most common progressive neurodegenerative disease worldwide, but its cause remains unclear. Although a few drugs can provide temporary and partial relief of symptoms in some patients, no curative treatment is availab
Autor:
Hyun Jung Hong, Kyong Hye Joung, Yong Kyung Kim, Min Jeong Choi, Seul Gi Kang, Jung Tae Kim, Yea Eun Kang, Joon Young Chang, Joon Ho Moon, Sangmi Jun, Hyun-Joo Ro, Yujeong Lee, Hyeongseok Kim, Jae-Hyung Park, Baeki E. Kang, Yunju Jo, Heejung Choi, Dongryeol Ryu, Chul-Ho Lee, Hail Kim, Kyu-Sang Park, Hyun Jin Kim, Minho Shong
Publikováno v:
Experimentalmolecular medicine. 54(7)
Genetic variations in mitoribosomal subunits and mitochondrial transcription factors are related to type 2 diabetes. However, the role of islet mitoribosomes in the development of type 2 diabetes has not been determined. We investigated the effects o
Autor:
Ha Young Lee, Chang-Seop Lee, Edmond Changkyun Park, Sangmi Jun, Hwang Jm, Seung Il Kim, Yujeong Lee, Yoon-Sun Yi
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 12, Pp 3101-3103 (2020)
Emerging Infectious Diseases
Emerging Infectious Diseases
Scrub typhus, the third most frequently reported infectious disease in South Korea, causes serious public health problems. In 2019, we collected a bile specimen from a patient with scrub typhus through percutaneous transhepatic gallbladder drainage a
Publikováno v:
ACS chemical biology. 14(12)
Oxidative damage in DNA is one of the primary sources of mutations in the cell. The activities of repair enzymes 8-oxoguanine DNA glycosylase (OGG1) and human MutT Homologue 1 (NUDT1 or MTH1), which work together to ameliorate this damage, are closel
Publikováno v:
Archives of Pharmacal Research. 40:1117-1128
Parkinson's disease (PD) is the second most common progressive neurodegenerative disease after Alzheimer's disease. PD exhibits clinical symptoms that include tremors, rigidity, and bradykinesia. Many drugs are available to treat PD, such as, L-dopa,
Significant roles of neuroinflammation in Parkinson's disease: therapeutic targets for PD prevention
Publikováno v:
Archives of pharmacal research. 42(5)
Glial cells outnumber neurons in the brain and play important roles in the neuroinflammation that accompanies brain damage in neurodegenerative diseases. In Parkinson's disease (PD), dopaminergic neuronal loss is accompanied by inflammatory changes i
Publikováno v:
Bioconjugate chemistry. 29(5)
Nucleotide surveillance enzymes play important roles in human health, by monitoring damaged monomers in the nucleotide pool and deactivating them before they are incorporated into chromosomal DNA or disrupt nucleotide metabolism. In particular, deami