Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Youyi Zhang"'
Autor:
Khader Shameer, Youyi Zhang, Andrzej Prokop, Sreenath Nampally, Imran Khan A. N, Jim Weatherall, Renee Bailey Iacona, Faisal M. Khan
Publikováno v:
JCO Clinical Cancer Informatics.
PURPOSE Overall survival (OS) is the gold standard end point for establishing clinical benefits in phase III oncology trials. However, these trials are associated with low success rates, largely driven by failure to meet the primary end point. Surrog
Publikováno v:
BMC Cancer. 22
Background Accumulating evidence suggests that LINC00511 acts as an oncogenic long non-coding RNA (lncRNA) in various cancers, including lung adenocarcinoma (LUAD). Hence, we attempted to elucidate the potential role of LINC00511 in LUAD. Methods LIN
Autor:
Youyi Zhang, Lantao Liu, Ning Hou, Yan Teng, Yao Song, Jiangping Song, Xiao Yang, Chong Xin, Xuan Cheng, Jingping Xu, Jian Wang, Tianle Wang, Zhenyang Yu, Zhenhua Li
Publikováno v:
Circulation research. 129(9)
Rationale: Protein O-GlcNAcylation is dynamically regulated by 2 key enzymes, OGT (O-GlcNAc transferase) and OGA (O-GlcNAcase). Excessive protein O-GlcNAcylation contributes to dilated cardiomyopathy (DCM), but its regulatory mechanisms are not fully
Autor:
Yajun, Bai, Pu, Jia, Ye, Zhao, Lingjian, Yang, Xiaoxiao, Wang, Xue, Wang, Jing, Wang, Ni'er, Zhong, Huaxiang, Deng, Linxiang, Du, Jiacheng, Fang, Yanbo, Xue, Yongyong, Chen, Shuomo, Gao, Ying, Feng, Yi, Yan, Tianzheng, Xiong, Jinbin, Liu, Ying, Sun, Jing, Xie, Xirui, He, Xuexia, An, Pei, Liu, Jinjin, Xu, Fanggang, Qin, Xue, Meng, Qian, Yin, Qiuxiang, Yang, Rong, Gao, Xiaokang, Gao, Kai, Luo, Qiannan, Li, Xing, Wang, Jing, Liang, Puye, Yang, Yajun, Zhang, Sha, Liao, Shixiang, Wang, Xinfeng, Zhao, Chaoni, Xiao, Jie, Yu, Qinshe, Liu, Rui, Wang, Ning, Peng, Xiaowen, Wang, Jianbo, Guo, Xia, Li, Haijing, Liu, Yan, Bai, Zijian, Li, Youyi, Zhang, Yefei, Nan, Qunzheng, Zhang, Xunli, Zhang, Jin'e, Lei, Erna, Alberts, Angélique, de Man, Hye Kyong, Kim, Su-Jung, Hsu, Yu Sheng, Jia, Joerg, Riener, Jianbin, Zheng, Wanbin, Zhang, Xiaopu, Zheng, Yujie, Cai, Mei, Wang, Tai-Ping, Fan, Xiaohui, Zheng
Publikováno v:
Pharmacological Research. 185:106458
Our initial studies detected elevated levels of 3,4-dihydroxyphenyllactic acid (DHPLA) in urine samples of patients with severe heart disease when compared with healthy subjects. Given the reported anti-inflammatory properties of DHPLA and related di
Publikováno v:
AMIA Annu Symp Proc
Combination therapies are an emerging drug development strategy in cancer, particularly in the immunooncology (IO) space. Many combination studies do not meet their safety objectives due to serious adverse events (SAEs). Prediction of SAEs based on e
Publikováno v:
Science China Life Sciences. 62:1038-1046
Macrophage migration inhibitory factor (MIF) is an inflammatory cytokine. It is elevated early in the blood of acute myocardial infarction patients. However, it is unclear whether and how MIF is released. This study investigated the cellular source a
Autor:
G.-J. Shan, S.-J. Cao, S.-N. Zhu, Youyi Zhang, Daqing Ma, Dong-Xin Wang, H.-J. Li, Yuelun Zhang
Publikováno v:
British Journal of Anaesthesia. 121:595-604
The choice of general anaesthetics may affect postoperative cognitive outcomes. This study was designed to compare the potential impact of propofol-based vs sevoflurane-based general anaesthesia on the development of delayed neurocognitive recovery i
Autor:
Lihua Qi, Hongquan Zhang, Yao Song, Shengchang Zhang, Xueqian Feng, Youyi Zhang, Yu Yu, Wenhui Chu, Xiaochun Chi, Xi Zhang, Wei Kong, Junzhou Wu
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 12, Pp 1-13 (2019)
Cell Death and Disease, Vol 10, Iss 12, Pp 1-13 (2019)
Kindlin-2 plays an important role in the regulation of cardiac structure and function. Depletion of Kindlin-2 contributes to cardiac hypertrophy and progressive heart failure, however, the precise mechanisms involved in this process remain unclear. G
Autor:
S.-N. Zhu, Daqing Ma, Dong-Xin Wang, Youyi Zhang, G.-J. Shan, H.-J. Li, S.-J. Cao, Yuelun Zhang
Publikováno v:
Acta Anaesthesiologica Scandinavica. 62:924-935
BACKGROUND Vitamin D is important for maintaining physiological functions including cognition and its deficiency is associated with the occurrence of cognitive impairment. This study was to explore the association between preoperative vitamin D statu
Autor:
Youyi Zhang, Yue Feng, Ai-Hua Zhang, Xiangbo An, Yao Song, Cong-Cong Zhang, Jing Shen, Jing-Jing Wang, Hao Li, Jianshu Zhang, Wei Gao, Jie Du, Jimin Wu, Haiyi Yu, Han Xiao, Xinyu Wang, Ming Xu, Zhizhen Lu, Zijian Li, Xiangning Deng
Publikováno v:
European Heart Journal
Aims Rapid over-activation of β-adrenergic receptor (β-AR) upon stress leads to cardiac inflammation, a prevailing factor that underlies heart injury. However, mechanisms by which acute β-AR stimulation induce cardiac inflammation still remain unk