Zobrazeno 1 - 10
of 23
pro vyhledávání: '"William E Janssen"'
Autor:
Mary Beth McCarville, Alberto S. Pappo, Barbara Rooney, William E. Janssen, Gwendolyn Anthony, April Sykes, Sara M. Federico, Amanda Sooter, Natasha Sahr, Michael A. Dyer, Wayne L. Furman, Brandon M. Triplett, Rosa Nguyen, Wing Leung, Aimee C Talleur, David Cullins
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
BackgroundNatural killer (NK) cells are one of the main effector populations of immunotherapy with monoclonal antibody and cytokines, used in combination with chemotherapy to treat children with high-risk neuroblastoma on this phase II trial. However
Autor:
Rachel C. Brennan, Barry L. Shulkin, Shenghua Mao, Alberto S. Pappo, Paul M. Sondel, M. Beth McCarville, Wayne L. Furman, Victor M. Santana, Wing Leung, Catherine Y.C. Ng, Paul R. Hutson, William E. Janssen, Aaron Shafer, Sara M. Federico, Michael M Meagher, Jianrong Wu, Jacquelyn A. Hank
Publikováno v:
Clin Cancer Res
Purpose: Anti-GD2 mAbs, acting via antibody-dependent cell-mediated cytotoxicity, may enhance the effects of chemotherapy. This pilot trial investigated a fixed dose of a unique anti-GD2 mAb, hu14.18K322A, combined with chemotherapy, cytokines, and h
Autor:
Norman J. Lacayo, Teresa M. Bell, Jeffrey E. Rubnitz, Ching-Hon Pui, William E. Janssen, Huiyun Wu, Barbara Rooney, Kenneth Heym, Raul C. Ribeiro, Stanley Pounds, Rosa Nguyen, Barbara A. Degar, Brandon M. Triplett, Deborah Schiff, Hiroto Inaba, David Cullins, Wing Leung
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-7 (2019)
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-7 (2019)
Consolidation therapies for children with intermediate- or high-risk acute myeloid leukemia (AML) are urgently needed to achieve higher cure rates while limiting therapy-related toxicities. We determined if adoptive transfer of natural killer (NK) ce
Autor:
Ewelina Mamcarz, Wayne L. Furman, Sara M. Federico, Jianrong Wu, William E. Janssen, Aimee C Talleur, Wing Leung, David Shook, Brandon M. Triplett
Publikováno v:
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 23(11)
The treatment of pediatric high-risk neuroblastoma is intensive and multimodal. Despite the introduction of immunotherapy for minimal residual disease, survival rates remain suboptimal and new therapies are needed. As part of a phase 2 trial, we are
Autor:
Leigh Turner, Lynn O'Donnell, Robert J. Deans, Robert E. Nordon, Kurt C. Gunter, William E. Janssen, Massimo Dominici, Steve D. Wilton, Edwin M. Horwitz, John E.J. Rasko, Dominic Wall, Edwin Wagena, Milton A. Ruiz, D.L. Griffin, Miguel Forte, Christopher E. Mason, Karen Nichols, Daniel J. Weiss, Hong Nerng Ho, Alok Srivastava, Paul Eldridge, Aaron D. Levine, Natividad Cuende
Publikováno v:
Cytotherapy. 17(12)
Currently, there are many unproven or insufficiently proven cell-based treatments commercially available for hopeful individuals seeking cures for a variety of conditions. Typically, these so-called “therapies” are currently being advertised, sol
Autor:
John K. Choi, Lea Cunningham, Wing Leung, Ewelina Mamcarz, David Shook, Ashok Srinivasan, Brandon M. Triplett, Guolian Kang, Joseph Moen, Ying Li, Randall T. Hayden, Brad Muller, William E. Janssen, Shane J Cross
Publikováno v:
Transplant Infectious Disease. 20:e12823
BACKGROUND T-cell depletion (TCD) effectively reduces severe graft-versus-host disease in recipients of HLA-mismatched allografts. However, TCD is associated with delayed immune recovery and increased infections. We hypothesized that specific depleti
Autor:
Ernesto Ayala, Janelle Perkins, Melissa Alsina, Mohamed A. Kharfan-Dabaja, Y Huang, Alan F. List, Lia Perez, Claudio Anasetti, Hugo F. Fernandez, Daniel M. Sullivan, J.E. Lancet, Teresa Field, William E. Janssen
Publikováno v:
Bone Marrow Transplantation. 45:255-260
Relapse remains a leading cause for treatment failure after hematopoietic cell transplantation (HCT) in patients with intermediate- or high-risk myelodysplastic syndrome (MDS). To discern the impact of 5-azacitine treatment pretransplant on the risk
Autor:
Renee Smilee, William E. Janssen, David Boulware, Clay Smith, Tracy Gentry, Paul Fallon, Robert W. Storms, Andrew E. Balber
Publikováno v:
British Journal of Haematology. 122:99-108
We have developed an approach for identifying primitive mobilized peripheral blood cells (PBSC) that express high levels of aldehyde dehydrogenase (ALDH). PBSC were stained with a fluorescent ALDH substrate, termed BODIPY trade mark -aminoacetaldehyd
Autor:
Peter Holman, Thomas A. Lane, Anthony D. Ho, Edward D. Ball, EA Gilpin, O. Santos-Ada, Asad Bashey, Sue Corringham, K.K. Fields, Smilee R, William E. Janssen, Ping Law, C. DeFrancisco
Publikováno v:
Cytotherapy. 2:195-200
Background A proportion of candidates for high-dose chemotherapy with autologous PBPC support (HDC-PBPCS) will not provide an adequate PBPC yield from their first mobilization. The value of re-mobilization and the best regimen for re-mobilization in
Autor:
Janelle Perkins, Lynn C. Moscinski, Karen K. Fields, G. J. Elfenbein, William E. Janssen, W L Trudeau
Publikováno v:
Journal of Clinical Oncology. 14:1868-1876
PURPOSE The present study evaluates the clinical significance of detection of cytokeratin 19 (K19) in the bone marrow of patients with breast cancer undergoing high-dose chemotherapy (HDCT) and autologous bone marrow transplantation (ABMT). PATIENTS