Zobrazeno 11 - 20
of 27
pro vyhledávání: '"Stephen H. Bryant"'
Autor:
Eric W. Sayers, Tanya Barrett, Dennis A. Benson, Evan Bolton, Stephen H. Bryant, Kathi Canese, Vyacheslav Chetvernin, Deanna M. Church, Michael DiCuccio, Scott Federhen, Michael Feolo, Lewis Y. Geer, Wolfgang Helmberg, Yuri Kapustin, David Landsman, David J. Lipman, Zhiyong Lu, Thomas L. Madden, Tom Madej, Donna R. Maglott, Aron Marchler-Bauer, Vadim Miller, Ilene Mizrachi, James Ostell, Anna Panchenko, Kim D. Pruitt, Gregory D. Schuler, Edwin Sequeira, Stephen T. Sherry, Martin Shumway, Karl Sirotkin, Douglas Slotta, Alexandre Souvorov, Grigory Starchenko, Tatiana A. Tatusova, Lukas Wagner, Yanli Wang, W. John Wilbur, Eugene Yaschenko, Jian Ye
Publikováno v:
Nucleic Acids Research
Scopus-Elsevier
Scopus-Elsevier
In addition to maintaining the GenBank® nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through the N
Autor:
Thomas Madej, Manoj Tyagi, Benjamin A. Shoemaker, Aron Marchler-Bauer, Dachuan Zhang, Stephen H. Bryant, Ratna R. Thangudu, Anna R. Panchenko, Jessica H. Fong
Publikováno v:
Nucleic Acids Research
IBIS is the NCBI Inferred Biomolecular Interaction Server. This server organizes, analyzes and predicts interaction partners and locations of binding sites in proteins. IBIS provides annotations for different types of binding partners (protein, chemi
Publikováno v:
Journal of Chemical Information and Modeling
Sixteen FDA-approved drugs were investigated to elucidate their mechanisms of action (MOAs) and clinical functions by pathway analysis based on retrieved drug targets interacting with or affected by the investigated drugs. Protein and gene targets an
Publikováno v:
Journal of Molecular Graphics and Modelling
Cathepsin B has been found being responsible for many human diseases. Inhibitors of cathepsin B, a ubiquitous lysosomal cysteine protease, have been developed as a promising treatment for human diseases resulting from malfunction and over-expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dac7d7de7f2c4b6c87cb1877a09e4ca
https://europepmc.org/articles/PMC3167229/
https://europepmc.org/articles/PMC3167229/
Publikováno v:
Database: The Journal of Biological Databases and Curation
New generation sequencing technologies have resulted in significant increases in the number of complete genomes. Functional characterization of these genomes, such as by high-throughput proteomics, is an important but challenging task due to the diff
Publikováno v:
Drug discovery today. 15(23-24)
PubChem is a public repository of small molecules and their biological properties. Currently, it contains over 25 million unique chemical structures and 90 million bioactivity outcomes associated with several thousand macromolecular targets. To addre
Autor:
Wenyao Shi, Stephen H. Bryant, Jane He, Aron Marchler-Bauer, Renata C. Geer, Lianyi Han, Siqian He, Chunlei Liu, Lewis Y. Geer
Publikováno v:
Nucleic Acids Research
The NCBI BioSystems database, found at http://www.ncbi.nlm.nih.gov/biosystems/, centralizes and cross-links existing biological systems databases, increasing their utility and target audience by integrating their pathways and systems into NCBI resour
Publikováno v:
Journal of molecular biology. 395(4)
The evolution of protein interactions cannot be deciphered without a detailed analysis of interaction interfaces and binding modes. We performed a large-scale study of protein homooligomers in terms of their symmetry, interface sizes, and conservatio
Publikováno v:
Genome research. 12(10)
The Conserved Domain Architecture Retrieval Tool (CDART) performs similarity searches of the NCBI Entrez Protein Database based on domain architecture, defined as the sequential order of conserved domains in proteins. The algorithm finds protein simi
Autor:
Stephen H. Bryant, Benjamin A. Shoemaker, David I. Hurwitz, Cynthia A. Liebert, Gabriele H. Marchler, Jie Chen, Lewis Y. Geer, Paul A. Thiessen, Yanli Wang, Aron Marchler-Bauer, Thomas Madej, James S. Song, Siqian He, Anna R. Panchenko, John B. Anderson, Roxanne A. Yamashita
Publikováno v:
Nucleic acids research. 30(1)
Three-dimensional structures are now known within many protein families and it is quite likely, in searching a sequence database, that one will encounter a homolog with known structure. The goal of Entrez’s 3D-structure database is to make this inf