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pro vyhledávání: '"Sarah Elzinga"'
Publikováno v:
Clinical Epigenetics
Diabetic peripheral neuropathy (DPN) is the most common complication of type 2 diabetes (T2D). Although the cellular and molecular mechanisms of DPN are poorly understood, we and others have shown that altered gene expression and DNA methylation are
Autor:
Junguk Hur, Eva L. Feldman, Stephanie Eid, Sarah Elzinga, Crystal Pacut, Kai Guo, Claudia Figueroa-Romero, Lucy M. Hinder
Publikováno v:
Epigenetics
DNA methylation is an epigenetic mechanism important for the regulation of gene expression, which plays a vital role in the interaction between genetic and environmental factors. Aberrant epigenetic changes are implicated in the pathogenesis of diabe
Autor:
John M. Hayes, Junguk Hur, Maegan A. Tabbey, Kai Guo, Sarah Elzinga, Benjamin J. Murdock, Eva L. Feldman
Publikováno v:
Exp Neurol
Neuropathy is a common, morbid complication of the metabolic syndrome, prediabetes, and diabetes. Recent studies have indicated a potential role for the immune system in the development of neuropathy. In particular, toll-like receptors (TLR) 2 and 4