Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Ryo, Ito"'
Publikováno v:
BMJ case reports. 15(8)
Autor:
Yuta Tsujisaka, Takeshi Hatani, Chikako Okubo, Ryo Ito, Azuma Kimura, Megumi Narita, Kazuhisa Chonabayashi, Shunsuke Funakoshi, Antonio Lucena-Cacace, Taro Toyoda, Kenji Osafune, Takeshi Kimura, Hirohide Saito, Yoshinori Yoshida
Publikováno v:
Stem Cell Reports. 17:1772-1785
For regenerative cell therapies using pluripotent stem cell (PSC)-derived cells, large quantities of purified cells are required. Magnetic-activated cell sorting (MACS) is a powerful approach to collect target antigen-positive cells; however, it rema
Autor:
Ryo Ito, Hanae Morio, Tomoyo Baba, Yasuyuki Sakaguchi, Naomi Wakayama, Ryuto Isogai, Yoshiyuki Yamaura, Takafumi Komori, Tomomi Furihata
Publikováno v:
Pharmaceutical Research. 39:1575-1586
In vitro human blood-brain barrier (BBB) models in combination with central nervous system-physiologically based pharmacokinetic (CNS-PBPK) modeling, hereafter referred to as the "BBB/PBPK" method, are expected to contribute to prediction of brain dr
Autor:
Yoshio Kobayashi, Miyo Nakano, Yusuke Kondo, Ryo Ito, Haruhiro Takahira, Masahiro Nakano, Toshinori Chiba, Takatsugu Kajiyama, Mari Kitagawa, Masafumi Sugawara
Publikováno v:
Journal of Cardiology. 78:362-367
It is unclear whether there is any difference in the background and prognosis between non-elderly patients who undergo catheter ablation of atrial fibrillation (AF) and common atrial flutter (CAFL).To investigate the difference between the patient ba
Autor:
Keita Kitamura, Ayaka Okamoto, Hanae Morio, Ryuto Isogai, Ryo Ito, Yoshiyuki Yamaura, Saki Izumi, Takafumi Komori, Shingo Ito, Sumio Ohtsuki, Hidetaka Akita, Tomomi Furihata
Publikováno v:
Molecular pharmaceutics. 19(8)
Blood-brain barrier (BBB)-permeable middle- or macromolecules (middle/macromolecules) have recently attracted significant attention as new drug delivery carriers into the human brain via receptor-mediated transcytosis (RMT). During the development pr
Autor:
Mai Mochizuki, Sadafumi Kawamura, Kazuto Matsuura, Keiichi Tamai, Takayuki Imai, Wataru Iwai, Jun Yasuda, Akira Sugawara, Yukinori Asada, Makoto Abue, Tomoko Yamazaki, Haruna Fujimori, Rie Shibuya-Takahashi, Satoshi Saijoh, Ryo Ito, Yukio Katori, Mao Nakamura-Shima, Kazuo Sugamura, Kazunori Yamaguchi, Yu Katayose, Yuta Wakui, Kennichi Satoh
Publikováno v:
Biochemical and Biophysical Research Communications. 537:132-139
Cancer stem cells (CSCs) are believed to cause cancer metastasis and recurrence. BEX2 (brain expressed X-linked gene 2) is a CSC-related gene that is expressed in dormant CSCs in cholangiocarcinoma and induces resistance against chemotherapy. The aim
Publikováno v:
Biochemical and Biophysical Research Communications. 534:672-679
Aldosterone is synthesized in the adrenal by the aldosterone synthase CYP11B2. Although the control of CYP11B2 expression is important to maintain the mineral homeostasis, its overexpression induced by the depolarization-induced calcium (Ca2+) signal
FABP7 Regulates Acetyl-CoA Metabolism Through the Interaction with ACLY in the Nucleus of Astrocytes
Autor:
Yuji Owada, Masayuki Kanamori, Kosuke Jozaki, Shuhei Kobayashi, Subrata Kumar Shil, Ryo Zama, Hiroshi Kogo, Ariful Islam, Kazuhiko Igarashi, Hirofumi Miyazaki, Chie Shimamoto-Mitsuyama, Yoshiteru Kagawa, Shin Ichiro Kanno, Banlanjo Abdulaziz Umaru, Shun Sato, Ryo Ito, Teiji Tominaga, Hiroki Shima, Akira Yasui, Kohji Fukunaga, Yui Yamamoto, Takeo Yoshikawa, Norihiro Sugino, Akira Sugawara
Publikováno v:
Molecular Neurobiology
Fatty acid binding protein 7 (FABP7) is an intracellular fatty acid chaperon that is highly expressed in astrocytes, oligodendrocyte-precursor cells, and malignant glioma. Previously, we reported that FABP7 regulates the response to extracellular sti
Autor:
Ryo Suenaga, Shuhei Konagaya, Junji Yamaura, Ryo Ito, Satoshi Tanaka, Yoichi Ishizaki, Taro Toyoda
Publikováno v:
Scientific reports. 12(1)
Pluripotent stem-cell derived cells can be used for type I diabetes treatment, but we require at least 10⁵–10⁶ islet-like clusters per patient. Although thousands of uniform cell clusters can be produced using a conventional microwell plate, nu
Autor:
Toshiya Tanaka, Aoi Uchida, Takeshi Inagaki, Shogo Yamamoto, Tatsuhiko Kodama, Yoshihiro Matsumura, Ryo Ito, Yohei Abe, Youichiro Wada, Ryo Nakaki, Hiroyuki Aburatani, Koichi Node, Shuichi Tsutsumi, Rei Yamaguchi, Makoto Arai, Hitomi Fujihashi, Hiroki Takahashi, Ji Zhang, Kenta Magoori, Hiroyuki Hirakawa, Takeshi Kawamura, Hiroshi Kimura, Shin Ichi Inoue, Juro Sakai, Chaoran Yang, Ayumu Yajima, Timothy F. Osborne, Ge Yang, Satoshi Ota, Takeshi Yoneshiro
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature Communications
Enhancer activation is essential for cell-type specific gene expression during cellular differentiation, however, how enhancers transition from a hypoacetylated “primed” state to a hyperacetylated-active state is incompletely understood. Here, we