Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Phillips, Joanna J."'
Autor:
Lilly, Jena V., Rokita, Jo Lynne, Mason, Jennifer L., Patton, Tatiana, Stefankiewiz, Stephanie, Higgins, David, Trooskin, Gerri, Larouci, Carina A., Arya, Kamnaa, Appert, Elizabeth, Heath, Allison P., Zhu, Yuankun, Brown, Miguel A., Zhang, Bo, Farrow, Bailey K., Robins, Shannon, Morgan, Allison M., Nguyen, Thinh Q., Frenkel, Elizabeth, Lehmann, Kaitlin, Drake, Emily, Sullivan, Catherine, Plisiewicz, Alexa, Coleman, Noel, Patterson, Luke, Koptyra, Mateusz, Helili, Zeinab, Van Kuren, Nicholas, Young, Nathan, Kim, Meen Chul, Friedman, Christopher, Lubneuski, Alex, Blackden, Christopher, Williams, Marti, Baubet, Valerie, Tauhid, Lamiya, Galanaugh, Jamie, Boucher, Katie, Ijaz, Heba, Cole, Kristina A., Choudhari, Namrata, Santi, Mariarita, Moulder, Robert W., Waller, Jonathan, Rife, Whitney, Diskin, Sharon J., Mateos, Marion, Parsons, Donald W., Pollack, Ian F., Goldman, Stewart, Leary, Sarah, Caporalini, Chiara, Buccoliero, Anna Maria, Scagnet, Mirko, Haussler, David, Hanson, Derek, Firestein, Ron, Cain, Jason, Phillips, Joanna J., Gupta, Nalin, Mueller, Sabine, Grant, Gerald, Monje-Deisseroth, Michelle, Partap, Sonia, Greenfield, Jeffrey P., Hashizume, Rintaro, Smith, Amy, Zhu, Shida, Johnston, James M., Fangusaro, Jason R., Miller, Matthew, Wood, Matthew D., Gardner, Sharon, Carter, Claire L., Prolo, Laura M., Pisapia, Jared, Pehlivan, Katherine, Franson, Andrea, Niazi, Toba, Rubin, Josh, Abdelbaki, Mohamed, Ziegler, David S., Lindsay, Holly B., Stucklin, Ana Guerreiro, Gerber, Nicolas, Vaske, Olena M., Quinsey, Carolyn, Rood, Brian R., Nazarian, Javad, Raabe, Eric, Jackson, Eric M., Stapleton, Stacie, Lober, Robert M., Kram, David E., Koschmann, Carl, Storm, Phillip B., Lulla, Rishi R., Prados, Michael, Resnick, Adam C., Waanders, Angela J.
Pediatric brain tumors are the leading cause of cancer-related death in children in the United States and contribute a disproportionate number of potential years of life lost compared to adult cancers. Moreover, survivors frequently suffer long-term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4703576335093c7619af35efeced399c
https://escholarship.org/uc/item/5jd0x77q
https://escholarship.org/uc/item/5jd0x77q
Autor:
Hendrikse, Liam D, Haldipur, Parthiv, Saulnier, Olivier, Millman, Jake, Sjoboen, Alexandria H, Erickson, Anders W, Ong, Winnie, Gordon, Victor, Coudière-Morrison, Ludivine, Mercier, Audrey L, Shokouhian, Mohammad, Suárez, Raúl A, Ly, Michelle, Borlase, Stephanie, Scott, David S, Vladoiu, Maria C, Farooq, Hamza, Sirbu, Olga, Nakashima, Takuma, Nambu, Shohei, Funakoshi, Yusuke, Bahcheli, Alec, Diaz-Mejia, J Javier, Golser, Joseph, Bach, Kathleen, Phuong-Bao, Tram, Skowron, Patryk, Wang, Evan Y, Kumar, Sachin A, Balin, Polina, Visvanathan, Abhirami, Lee, John JY, Ayoub, Ramy, Chen, Xin, Chen, Xiaodi, Mungall, Karen L, Luu, Betty, Bérubé, Pierre, Wang, Yu C, Pfister, Stefan M, Kim, Seung-Ki, Delattre, Olivier, Bourdeaut, Franck, Doz, François, Masliah-Planchon, Julien, Grajkowska, Wieslawa A, Loukides, James, Dirks, Peter, Fèvre-Montange, Michelle, Jouvet, Anne, French, Pim J, Kros, Johan M, Zitterbart, Karel, Bailey, Swneke D, Eberhart, Charles G, Rao, Amulya AN, Giannini, Caterina, Olson, James M, Garami, Miklós, Hauser, Peter, Phillips, Joanna J, Ra, Young S, de Torres, Carmen, Mora, Jaume, Li, Kay KW, Ng, Ho-Keung, Poon, Wai S, Pollack, Ian F, López-Aguilar, Enrique, Gillespie, G Yancey, Van Meter, Timothy E, Shofuda, Tomoko, Vibhakar, Rajeev, Thompson, Reid C, Cooper, Michael K, Rubin, Joshua B, Kumabe, Toshihiro, Jung, Shin, Lach, Boleslaw, Iolascon, Achille, Ferrucci, Veronica, de Antonellis, Pasqualino, Zollo, Massimo, Cinalli, Giuseppe, Robinson, Shenandoah, Stearns, Duncan S, Van Meir, Erwin G, Porrati, Paola, Finocchiaro, Gaetano, Massimino, Maura, Carlotti, Carlos G, Faria, Claudia C, Roussel, Martine F, Boop, Frederick, Chan, Jennifer A, Aldinger, Kimberly A, Razavi, Ferechte, Silvestri, Evelina, McLendon, Roger E, Thompson, Eric M
Publikováno v:
Nature, vol 609, iss 7929
Medulloblastoma (MB) comprises a group of heterogeneous paediatric embryonal neoplasms of the hindbrain with strong links to early development of the hindbrain1-4. Mutations that activate Sonic hedgehog signalling lead to Sonic hedgehog MB in the upp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::8faf54a082e7566ea11ba2a3cd7e3d2c
https://escholarship.org/uc/item/7c06j01k
https://escholarship.org/uc/item/7c06j01k
Autor:
Cluceru, Julia, Interian, Yannet, Phillips, Joanna J, Molinaro, Annette M, Luks, Tracy L, Alcaide-Leon, Paula, Olson, Marram P, Nair, Devika, LaFontaine, Marisa, Shai, Anny, Chunduru, Pranathi, Pedoia, Valentina, Villanueva-Meyer, Javier E, Chang, Susan M, Lupo, Janine M
Publikováno v:
Neuro-oncology, vol 24, iss 4
BackgroundDiagnostic classification of diffuse gliomas now requires an assessment of molecular features, often including IDH-mutation and 1p19q-codeletion status. Because genetic testing requires an invasive process, an alternative noninvasive approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::5fcb32c5435c478e3dffb0ac8ff78838
https://escholarship.org/uc/item/2186j7pf
https://escholarship.org/uc/item/2186j7pf
Autor:
Ohkawa, Yuki, Wade, Anna, Lindberg, Olle R, Chen, Katharine Y, Tran, Vy M, Brown, Spencer J, Kumar, Anupam, Kalita, Mausam, James, C David, Phillips, Joanna J
Publikováno v:
Molecular cancer research : MCR, vol 19, iss 1
Signaling from multiple receptor tyrosine kinases (RTK) contributes to therapeutic resistance in glioblastoma (GBM). Heparan sulfate (HS), present on cell surfaces and in the extracellular matrix, regulates cell signaling via several mechanisms. To i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::2f92febf9115d87d43f625a0c3b67665
https://escholarship.org/uc/item/7936z38n
https://escholarship.org/uc/item/7936z38n
Autor:
Wong, Robyn A, Luo, Xujun, Lu, Mimi, An, Zhenyi, Haas-Kogan, Daphne A, Phillips, Joanna J, Shokat, Kevan M, Weiss, William A, Fan, Qi Wen
Publikováno v:
Cancer research, vol 80, iss 4
The mTOR signaling is dysregulated prominently in human cancers including glioblastoma, suggesting mTOR as a robust target for therapy. Inhibitors of mTOR have had limited success clinically, however, in part because their mechanism of action is cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::973d1642f346005d1bdd6e53e17a3ca8
https://escholarship.org/uc/item/2c52w42q
https://escholarship.org/uc/item/2c52w42q
Autor:
Huang, Miller, Tailor, Jignesh, Zhen, Qiqi, Gillmor, Aaron H, Miller, Matthew L, Weishaupt, Holger, Chen, Justin, Zheng, Tina, Nash, Emily K, McHenry, Lauren K, An, Zhenyi, Ye, Fubaiyang, Takashima, Yasuhiro, Clarke, James, Ayetey, Harold, Cavalli, Florence MG, Luu, Betty, Moriarity, Branden S, Ilkhanizadeh, Shirin, Chavez, Lukas, Yu, Chunying, Kurian, Kathreena M, Magnaldo, Thierry, Sevenet, Nicolas, Koch, Philipp, Pollard, Steven M, Dirks, Peter, Snyder, Michael P, Largaespada, David A, Cho, Yoon Jae, Phillips, Joanna J, Swartling, Fredrik J, Morrissy, A Sorana, Kool, Marcel, Pfister, Stefan M, Taylor, Michael D, Smith, Austin, Weiss, William A
Publikováno v:
Cell stem cell, vol 25, iss 3
Huang, M, Tailor, J, Zhen, Q, Gillmor, A H, Miller, M L, Weishaupt, H, Chen, J, Zheng, T, Nash, E K, McHenry, L K, An, Z, Ye, F, Takashima, Y, Clarke, J, Ayetey, H, Cavalli, F M G, Luu, B, Moriarity, B S, Ilkhanizadeh, S, Chavez, L, Yu, C, Kurian, K M, Magnaldo, T, Sevenet, N, Koch, P, Pollard, S M, Dirks, P, Snyder, M P, Largaespada, D A, Cho, Y J, Phillips, J J, Swartling, F J, Morrissy, A S, Kool, M, Pfister, S M, Taylor, M D, Smith, A & Weiss, W A 2019, ' Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis ', Cell Stem Cell, vol. 25, no. 3, pp. 433-446.e7 . https://doi.org/10.1016/j.stem.2019.05.013
Cell stem cell
Huang, M, Tailor, J, Zhen, Q, Gillmor, A H, Miller, M L, Weishaupt, H, Chen, J, Zheng, T, Nash, E K, McHenry, L K, An, Z, Ye, F, Takashima, Y, Clarke, J, Ayetey, H, Cavalli, F M G, Luu, B, Moriarity, B S, Ilkhanizadeh, S, Chavez, L, Yu, C, Kurian, K M, Magnaldo, T, Sevenet, N, Koch, P, Pollard, S M, Dirks, P, Snyder, M P, Largaespada, D A, Cho, Y J, Phillips, J J, Swartling, F J, Morrissy, A S, Kool, M, Pfister, S M, Taylor, M D, Smith, A & Weiss, W A 2019, ' Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis ', Cell Stem Cell, vol. 25, no. 3, pp. 433-446.e7 . https://doi.org/10.1016/j.stem.2019.05.013
Cell stem cell
SUMMARY Human neural stem cell cultures provide progenitor cells that are potential cells of origin for brain cancers. However, the extent to which genetic predisposition to tumor formation can be faithfully captured in stem cell lines is uncertain.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a7a8581193724542cbe0a79f70f842
https://www.repository.cam.ac.uk/handle/1810/294953
https://www.repository.cam.ac.uk/handle/1810/294953
Autor:
Pekmezci, Melike, Stevers, Meredith, Phillips, Joanna J, Van Ziffle, Jessica, Bastian, Boris C, Tsankova, Nadejda M, Kleinschmidt-DeMasters, Bette K, Rosenblum, Marc K, Tihan, Tarik, Perry, Arie, Solomon, David A
Publikováno v:
Acta neuropathologica, vol 135, iss 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6065eb7a26427a6dfb46712064a77d2b
https://escholarship.org/uc/item/688638f1
https://escholarship.org/uc/item/688638f1
Autor:
Wahl, Michael, Chang, Susan M, Phillips, Joanna J, Molinaro, Annette M, Costello, Joseph F, Mazor, Tali, Alexandrescu, Sanda, Lupo, Janine M, Nelson, Sarah J, Berger, Mitchel, Prados, Michael, Taylor, Jennie W, Butowski, Nicholas, Clarke, Jennifer L, Haas-Kogan, Daphne
Publikováno v:
Cancer, vol 123, iss 23
BackgroundActivation of the phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) pathway is common in patients with low-grade gliomas (LGGs), but agents that inhibit this pathway, including mTOR inhibitors, have not been studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::086cff7d2f11db2db7a4e352baafcd90
https://escholarship.org/uc/item/4zh0w1tf
https://escholarship.org/uc/item/4zh0w1tf
Autor:
Wahl, Michael, Phillips, Joanna J, Molinaro, Annette M, Lin, Yi, Perry, Arie, Haas-Kogan, Daphne A, Costello, Joseph F, Dayal, Manisha, Butowski, Nicholas, Clarke, Jennifer L, Prados, Michael, Nelson, Sarah, Berger, Mitchel S, Chang, Susan M
Publikováno v:
Neuro-oncology, vol 19, iss 2
BackgroundOptimal adjuvant management of adult low-grade gliomas is controversial. Recently described tumor classification based on molecular subtype has the potential to individualize adjuvant therapy but has not yet been evaluated as part of a pros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::5d96f4f985696411e4a34d48d2ba21cf
https://escholarship.org/uc/item/1rf0k7bf
https://escholarship.org/uc/item/1rf0k7bf
Autor:
Miroshnikova, Yekaterina A, Mouw, Janna K, Barnes, J Matthew, Pickup, Michael W, Lakins, Johnathan N, Kim, Youngmi, Lobo, Khadjia, Persson, Anders I, Reis, Gerald F, McKnight, Tracy R, Holland, Eric C, Phillips, Joanna J, Weaver, Valerie M
Publikováno v:
Nature cell biology, vol 18, iss 12
Increased overall survival for patients with glioma brain tumours is associated with mutations in the metabolic regulator isocitrate dehydrogenase 1 (IDH1). Gliomas develop within a mechanically challenged microenvironment that is characterized by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::09c5ee9398292aaa396f9bbedc753495
https://escholarship.org/uc/item/4283m7q0
https://escholarship.org/uc/item/4283m7q0