Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Natali Gulbahce"'
Autor:
Erin E. Peters, Zhenyu Li, Natali Gulbahce, Wenwei Zhang, Rebecca Yu Zhang, Radoje Drmanac, Robert Chin, Huixin Xu, Yuqing Deng, Weiwei Xie, Fang Chen, Qing Mao, Quan Shi, Brock A. Peters
Publikováno v:
Clinical Chemistry. 64:715-725
BACKGROUND Amniocentesis is a common procedure, the primary purpose of which is to collect cells from the fetus to allow testing for abnormal chromosomes, altered chromosomal copy number, or a small number of genes that have small single- to multibas
Autor:
Raphael H. Valdivia, Jessica Sherry, Tasha L. Johnson, Michael Shales, Nevan J. Krogan, Michael N. Starnbach, Joe Dan Dunn, Natali Gulbahce, Jeffery S. Cox, Gwendolyn M. Jang, Andrew J. Olive, Oren S. Rosenberg, Kathleen M. Mirrashidi, Isabelle Derré, John Von Dollen, Andrew Frando, Cherilyn A. Elwell, Erik Verschueren, Bennett H. Penn, Stefanie Jäger, Anusha M. Gopalakrishnan, Joanne N. Engel, Jeffrey R. Johnson
Publikováno v:
Cell host & microbe, vol 18, iss 1
Summary Chlamydia trachomatis is a leading cause of genital and ocular infections for which no vaccine exists. Upon entry into host cells, C. trachomatis resides within a membrane-bound compartment—the inclusion—and secretes inclusion membrane pr
Autor:
R. Prates, Radoje Drmanac, Birgit Crain, Misha R. Agarwal, Brock A. Peters, Oleg Alferov, Mark A. McElwain, Rebecca Yu Zhang, Daniel M. Hayden, Rick Tearle, Natali Gulbahce, Alan S. Berkeley, Y. Tom Tang, Santiago Munné, Bahram Ghaffarzadeh Kermani
Publikováno v:
Genome Research. 25:426-434
Currently, the methods available for preimplantation genetic diagnosis (PGD) of in vitro fertilized (IVF) embryos do not detect de novo single-nucleotide and short indel mutations, which have been shown to cause a large fraction of genetic diseases.
Autor:
Robert Chin, Qing Mao, Zhenyu Li, Hope S. Rugo, Radoje Drmanac, Snezana Drmanac, Xingpeng Chen, Katharine Lee, Yuxiang Li, Brock A. Peters, Rick Tearle, Xuhao Luo, Natali Gulbahce, Daniel M. Hayden, Misha R. Agarwal, Yanxiang Chen, Emily Park, Rebecca Yu Zhang, Jia Liu, Mark Jesus M. Magbanua, Serban Ciotlos, John W. Park
Publikováno v:
Cancer research. 77(16)
Much effort has been dedicated to developing circulating tumor cells (CTC) as a noninvasive cancer biopsy, but with limited success as yet. In this study, we combine a method for isolation of highly pure CTCs using immunomagnetic enrichment/fluoresce
Autor:
William Stedman, Han Cao, Michael Saghbini, Jason Bobe, Alex Hastie, David Catoe, Arend Sidow, Marc L. Salit, Kristina Giorda, Alexander Wait Zaranek, Stephen T. Sherry, Zeljko Dzakula, Gintaras Deikus, R Truty, Erich Jaeger, Alexa B. R. McIntyre, Karoline Bjarnesdatter Rypdal, Christopher C. Chang, Robert Sebra, Srinka Ghosh, Grace X.Y. Zheng, Jonathan Trow, Yuling Liu, Tiffany Y. Liang, Khoa Pham, Fiona Hyland, Heather Ordonez, Dhruva Chandramohan, Noah Spies, Ziming Weng, Sofia Kyriazopoulou-Panagiotopoulou, Yutao Fu, Eric E. Schadt, Lindsay K. Vang, Ali Bashir, Madeleine Ball, Christopher E. Mason, Preston W. Estep, Keyan Zhao, George M. Church, Justin M. Zook, Ying Sheng, Mark Chaisson, Patrick Marks, Natali Gulbahce, Elizabeth Henaff, Patrice A Mudivarti, Feng Chen, Jennifer McDaniel, Michael Schnall-Levin, Chunlin Xiao, Noah Alexander, Ali Moshrefi
Publikováno v:
Scientific Data
BMC Genomics
BMC Genomics
Background The human genome contains variants ranging in size from small single nucleotide polymorphisms (SNPs) to large structural variants (SVs). High-quality benchmark small variant calls for the pilot National Institute of Standards and Technolog
Autor:
Kelan G. Tantisira, Conway C. Huang, Maksim Kitsak, Benjamin A. Raby, Weiliang Qiu, Edwin K. Silverman, Scott T. Weiss, Amitabh Sharma, Nidhi Sahni, Xiaobo Zhou, Radu Dobrin, Hao Liu, Albert-László Barabási, Linh Voung, Joel Tocker, Marc Vidal, Elliot S. Barnathan, Susan Dina Ghiassian, Frédéric Baribaud, Natali Gulbahce, Tatiana Ort, Feng Guo, Derek Thibault, Jörg Menche, Reynold A. Panettieri
Publikováno v:
Human molecular genetics. 24(11)
Recent advances in genetics have spurred rapid progress towards the systematic identification of genes involved in complex diseases. Still, the detailed understanding of the molecular and physiological mechanisms through which these genes affect dise
Autor:
Alyce A. Chen, David E. Hill, Amy M. Holthaus, Theodore R. Pak, Mariet C.W. Feltkamp, Danielle Byrdsong, James A. DeCaprio, Rachel Franchi, Melissa Duarte, Saurav Singh, Manor Askenazi, Orit Rozenblatt-Rosen, Jennifer M. Spangle, Rameen Beroukhim, Larisa Litovchick, Natali Gulbahce, Sam Pevzner, Miranda Grace, Sabrina Rabello, Karl Münger, Elliott Kieff, Anne-Ruxandra Carvunis, Yun Shen, Scott B. Ficarro, Thomas Rolland, Tong Hao, Brijesh K. Garg, Michael A. Calderwood, Anna Korkhin, Renee Rubio, Jessica C. Mar, Maria Tavares, Shelly Wanamaker, Murat Tasan, Frederick P. Roth, Fieda Abderazzaq, Robert James, James T. Webber, Albert-László Barabási, Jarrod A. Marto, Mick Correll, Changyu Fan, John Quackenbush, Megha Padi, Guillaume Adelmant, Rahul C. Deo, Amélie Dricot, Marc Vidal, Jingwei Cheng, Michael E. Cusick, Jennifer Roecklein-Canfield, Eric Johannsen
Publikováno v:
Nature, 487(7408), 491-495
Genotypic differences greatly influence susceptibility and resistance to disease. Understanding genotype-phenotype relationships requires that phenotypes be viewed as manifestations of network properties, rather than simply as the result of individua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c84d9cde906583091007b3dbfeaf34
https://hdl.handle.net/1887/106305
https://hdl.handle.net/1887/106305
Autor:
Han Yan, Karin Hellner, Marc Vidal, Jarrod A. Marto, Megha Padi, Jessica C. Mar, Amy Baldwin, Amélie Dricot, Danielle Byrdsong, Nicolas Simonis, Nicholas A. Christakis, Bo Zhao, David E. Hill, Alyce A. Chen, Karl Münger, Renee Rubio, Elliott Kieff, Frederick P. Roth, John Quackenbush, Michael A. Calderwood, Albert-László Barabási, Michael E. Cusick, Rachel Franchi, Deok-Sun Lee, Pascal Braun, Natali Gulbahce, Miranda Grace, Balaji Santhanam, Orit Rozenblatt-Rosen, Jennifer Roecklein-Canfield, James A. DeCaprio, Kyung-Won Huh
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 8, Iss 6, p e1002531 (2012)
PLoS computational biology, 8 (6
PLoS Computational Biology, Vol 8, Iss 6, p e1002531 (2012)
PLoS computational biology, 8 (6
Many human diseases, arising from mutations of disease susceptibility genes (genetic diseases), are also associated with viral infections (virally implicated diseases), either in a directly causal manner or by indirect associations. Here we examine w
Publikováno v:
Briefings in functional genomics. 10(5)
Despite the considerable progress in disease gene discovery, we are far from uncovering the underlying cellular mechanisms of diseases since complex traits, even many Mendelian diseases, cannot be explained by simple genotype ^ phenotype relationship
Autor:
Gwendolyn M. Jang, Stefanie Jäger, Jason D Fernandes, Tom Alber, Qiang Zhou, Alan D. Frankel, Seemay Chou, Peter Cimermancic, Nevan J. Krogan, Joshua Kane, Nanhai He, Natali Gulbahce, Iván D'Orso
Publikováno v:
Methods
To fully understand how pathogens infect their host and hijack key biological processes, systematic mapping of intra-pathogenic and pathogen–host protein–protein interactions (PPIs) is crucial. Due to the relatively small size of viral genomes (u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d80d8143ec79b90ad8f60208b8053b7
https://europepmc.org/articles/PMC3076283/
https://europepmc.org/articles/PMC3076283/