Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Luisa A. DiPietro"'
Autor:
Richard D. Minshall, Timothy J. Koh, Stephanie C. Wu, Na Xiong, Luisa A. DiPietro, Maria Sverdlov, Ying Jiang, Lin Chen, Jacob M. Haus, Zhenlong Chen
Chronic, non-healing skin wounds such as diabetic foot ulcers (DFUs) are common in patients with type 2 diabetes. Here, we investigated the role of chemokine CCL28 and its receptor CCR10 in downregulation of endothelial nitric oxide synthase (eNOS) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225d37258d4bb9a7b4d6aa57c1935c28
https://doi.org/10.2337/figshare.20360037.v1
https://doi.org/10.2337/figshare.20360037.v1
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 950, p 950 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 950, p 950 (2021)
Macrophages are prominent cells in normally healing adult skin wounds, yet their exact functions and functional significance to healing outcomes remain enigmatic. Many functional attributes are ascribed to wound macrophages, including host defense an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8a939f77035794a9c5479469aecb6f
Publikováno v:
Adv Wound Care (New Rochelle)
Significance: Millions of people worldwide suffer from diabetes mellitus and its complications, including chronic diabetic wounds. To date, there are few widely successful clinical therapies specific to diabetic wounds beyond general wound care, desp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ad9d272abb1f677ed184b18a8c4de80
https://europepmc.org/articles/PMC8236303/
https://europepmc.org/articles/PMC8236303/
Publikováno v:
FASEB J
The effective clearance of apoptotic cells is an essential step in the resolution of healing wounds. In particular, blood vessel regression during wound resolution produces a significant number of apoptotic endothelial cells (ApoEC) that must be clea
Autor:
Marjana Tomic-Canic, Luisa A. DiPietro
Publikováno v:
Journal of Investigative Dermatology. 139:997-999
Aging and cellular senescence are known contributors to the pathophysiology of diabetic nonhealing wounds. However, the dynamic interplay of senescent cells in diabetic wounds is not well understood. Wilkinson et al. show that macrophages, which cons
Autor:
Luisa A. DiPietro, Zujian Chen, Alyne Simões, Xinming Wu, Yan Zhao, Lin Chen, Xiaofeng Zhou, Yang Dai
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 15, p 3679 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 15
International Journal of Molecular Sciences
Volume 20
Issue 15
Wounds within the oral mucosa are known to heal more rapidly than skin wounds. Recent studies suggest that differences in the microRNAome profiles may underlie the exceptional healing that occurs in oral mucosa. Here, we test whether skin wound-heali
Autor:
Xiaofeng Zhou, Alyne Simões, Shang Gao, Yan Zhao, Yang Dai, Zujian Chen, Phillip T. Marucha, Lin Chen, Luisa A. DiPietro
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Oral mucosal wounds heal faster than skin wounds, yet the role of microRNAs in this differential healing has never been examined. To delineate the role of microRNAs in this site-specific injury response, we first compared the microRNAome of uninjured
Autor:
Luisa A. DiPietro
Publikováno v:
Journal of Leukocyte Biology. 100:979-984
All animals heal, and the ability to heal is requisite for human health. One aspect of repair that has always been considered to be essential for adequate healing is the creation of a new vasculature via angiogenesis. As adult skin wounds heal, a per
Autor:
Luisa A. DiPietro, Min Kyung Lee, Eunkyung Ko, John W. Schmidt, Jae Hyun Jeong, Hyunjoon Kong
Publikováno v:
Molecular Pharmaceutics. 13:2148-2154
Ever since proangiogenic growth factors have been used as a vascular medicine to treat tissue ischemia, efforts have been increasingly made to develop a method to enhance efficacy of growth factors in recreating microvascular networks, especially at
Autor:
Mateusz S. Wietecha, Lin Chen, Luisa A. DiPietro, Mateusz J. Król, Peter G.W. Gettins, Elizabeth R. Michalczyk
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 309:H812-H826
During dermal wound repair, hypoxia-driven proliferation results in dense but highly permeable, disorganized microvascular networks, similar to those in solid tumors. Concurrently, activated dermal fibroblasts generate an angiopermissive, provisional